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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Bacterial vector vaccine: Her-2/neu expressing tumors

    SBC: ADVAXIS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Advaxis will develop a novel Listeria monocytogenes based vaccine against the human HER-2/neu protein that will be a safe and effective therapeutic vaccine for the treatment of HER-2/neu overexpressing breast carcinomas. Breast cancer, the most common type of cancer in women, is a complex disease with no single causative agent or event. There are several tumor- ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  2. Modified Tetracycline Effect on Sepsis-Induced Mortality

    SBC: Collagenex Pharmaceuticals, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): It was our Specific Aim in Phase I to: 1) develop a clinically relevant indirect sepsis-induced acute respiratory distress syndrome (ARDS) model and 2) utilize this model to determine the efficacy of prophylactic COL-3 in preventing the onset of ARDS. Both goals of our Phase I study were achieved and the results are as follows: 1) we successfully developed an ...

    STTR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  3. A Decomposition Based Approach to Optimal Layout of Complex Systems such as UAV’s and Satellites

    SBC: Desantage Corporation            Topic: AF04T019

    The design of Unmanned Aerial Vehicles (UAV’s) is a complex process of creating a reliable system of reasonable cost that can survive in hostile environments. Although UAV’s have unique aspects to them, similar goals can be found in almost any complex, competitive product. One aspect of the design of these systems that tends to be both difficult and poorly supported with available computer ...

    STTR Phase II 2005 Department of DefenseAir Force
  4. High Temp High Energy Product Permanent Magnet Material

    SBC: ELECTRON ENERGY CORP            Topic: AF05T024

    The main objective of this program is to develop a new class of high performance hard magnetic materials that will maintain an energy product of 30 MGOe or greater at temperatures up to 450 °C. These novel magnetic materials are greatly needed for the "more electric" airplanes and space vehicle applications where a high operating temperature is a strict requirement. The approaches to be used for ...

    STTR Phase I 2005 Department of DefenseAir Force
  5. Fluorous Solution-Phase Synthesis of Peptides

    SBC: FLUOROUS TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Ready access to various oligosaccharides and glycopeptides is crucial for the development of glycobiology and glycomics-the system-wide study of the interactions of oligosaccharides with other biomolecules such as proteins. The long-term goal of the proposed project is to develop a new method for preparative scale syntheses of exceptionally pure oligopeptides, ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  6. Grid Management of Large-Scale Healthcare Data

    SBC: I3Archive, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The transition from analog to digital mammography will bring significant clinical benefits to the practice of mammography; i3ARCHIVE has developed digital mammographic systems for high volume electronic archiving with centralized execution of CAD algorithms. Digital systems of this type will facilitate the use of CAD algorithms, the movement of patient data fro ...

    STTR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  7. Gene Expression in Circulating Tumor Cells

    SBC: Immunicon Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): The informed development of new treatments for cancer would be greatly facilitated if tumor cells could be directly sampled at multiple time points following the administration of new drugs or drug combinations. Many new agents are not classic cytotoxics, but specifically target tumor cell biological processes or elements of the tumor stroma. In many cases, th ...

    STTR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  8. Calculation and Testing of Alternating Current (AC) Losses in Coated Conductors and the Development of Practical Conductors and Coils for Operational

    SBC: Long Electromagnetics, Inc.            Topic: AF03T023

    The use of coated HT superconductors in the ac windings of electrical machines offers the possibility of much lighter electrical devices. To use these conductors at proposed high frequencies, present “as-manufactured” conductor geometries must be modified to reduce their ac loss by using fine filaments and other topologies). Equally important are more global winding losses requiring suitable ...

    STTR Phase II 2005 Department of DefenseAir Force
  9. New Energetic Solid Propellant Ingredients

    SBC: MACH I Inc.            Topic: OSD05T001

    Boron has significant potential as a high energy density ingredient in ramjet propellants and fuels. This is due to boron's high heat of combustion and low atomic weight. For a ramjet ducted rocket, theoretical volume specific impulses of 1600- 1800 sec g cm-3 have been reported for a fuel rich boron solid propellant, 45 % greater than the best hydrocarbon composition. Boron's high ignition tem ...

    STTR Phase I 2005 Department of DefenseAir Force
  10. Lightweight Ambient Pressure/Temperature O2 Concentrator

    SBC: SEPARATION DESIGN GROUP, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Chronic Obstructive Pulmonary Disease (COPD) afflicts over 12 million Americans. One million COPD sufferers use Long Term Oxygen Therapy (LTOT) at an annual cost of nearly $2 billion. LTOT is the only medical treatment proven to prolong survival in COPD patients. In order to achieve this survival advantage, oxygen therapy must be prescribed and adhered to for a ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
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