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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Integrated Fiber-Optic Sensor Reliability Modeling and Analysis Tools for Thermal and Power Management Systems for Gas Turbine Engines

    SBC: INTELLIGENT FIBER OPTIC SYSTEMS CORP            Topic: AF16AT16

    Addressing a key technology gap in deployment of fiber-optic sensor networks, IFOS and multidisciplinary collaborators are developing an integrated fiber-optic component reliability modeling software toolkit. The RelOptics toolkits analytical engine is based upon predictive failure models developed for the first time in aerospace industry via rigorous environmental testing of optical fiber splices ...

    STTR Phase II 2017 Department of DefenseAir Force
  2. Intelligent and Multiplexable Ultra-High Temperature Fiber Optic Pressure Sensors for Robust Distributed Engine Control

    SBC: INTELLIGENT FIBER OPTIC SYSTEMS CORP            Topic: AF16AT18

    Engines will be getting smaller and hotter for efficiency reasons, requiring novel sensors with extended and enhanced performance. Emerging fiber-optic sensing approaches could provide a unique solution to the widening technology gap between next-gen engine requirements and conventional sensors limited capabilities. The overall objective of this program is to develop techniques to integrate new pr ...

    STTR Phase II 2017 Department of DefenseAir Force
  3. Breakthrough sub cellular D chemical composition research platform for live cells based on the new invention of nanoscale confocal photothermal IR micro spectroscopy n CPIR

    SBC: Anasys Instruments Corp.            Topic: 100

    Abstract This proposal will lead to a Breakthrough sub cellular D chemical composition research platform for live cells based on the new invention of sub micron confocal photothermal IR micro spectroscopy CPIR Label free sub micron chemical imaging and spectroscopy has long been sought for visualization of biomolecules and materials in complex living systems Many diseases first manifest ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Automated Electrophysiology Assessment of Drug induced Cardiotoxicity Based on Parallel Noninvasive Nanoelectrode Array

    SBC: CYION TECHNOLOGIES LLC            Topic: NIBIB

    Summary Drug safety issues pose a serious challenge to the health and well being of patients The development of our innovative technology aims to address a significant gap in the in vitro assessment of drug induced cardiotoxicity which is the number one reason for withdrawals of all marketed drugs as well as the premature termination of promising drug development candidates Pressured by the eno ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Novel Treatment for Traumatic Brain Injury

    SBC: Epigen Biosciences, Inc.            Topic: 101

    SUMMARY Traumatic brain injury TBI is a leading contributor to death and disability in the USA yet widely effective treatments remain elusive and except for a lengthy program of rehabilitation no effective treatment for TBI is available Therefore there is a critical need in new therapeutic approaches which can maximally preserve brain tissue and facilitate functional recovery after TBI In ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Development of Pirenzepine for HIV SN

    SBC: WinSanTor, Inc.            Topic: 101

    PROJECT SUMMARY Over million people worldwide including million people in the USA are HIV positive HIV associated sensory neuropathy HIV SN is the most frequent neurological manifestation of HIV and is characterized as a distal symmetrical predominantly sensory polyneuropathy HIV SN may represent clinically indistinguishable neuropathies with distinct pathogenesis a distal axona ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Novel therapy for Fragile X syndrome

    SBC: Epigen Biosciences, Inc.            Topic: 101

    PROJECT SUMMARY Fragile X syndromeFXSis the most common inheritable form of cognitive impairment and the leading known genetic cause of autismFXS is caused by the loss of expression of the fragile X mental retardation proteinFMRPA major challenge for FXS research is to develop treatment strategies that improve the intellectual capabilities of patientsDysregulated protein synthesis is widely accept ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Comprehensive Glycoproteomic Tool Development for Cancer Biomarkers

    SBC: PROTEIN METRICS INC            Topic: 400

    Project SummaryGlycosylation is one of the most prevalent and important post translational modifications of proteinsyet it is also one of the most difficult to studyNo single method nor analytical platform can give complete information about the glycosylation in a protein sampleand the analytical methods in current use include both ESI and MALDI single and tandem mass spectrometryat least four typ ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Highly-mobile Autonomous Rapidly Relocatable Integrated Electro-optical Resources (HARRIER)

    SBC: EXOANALYTIC SOLUTIONS INC            Topic: AF16AT05

    ExoAnalytic Solutions, teamed with Texas A&M University and Georgia Institute of Technology, will develop Highly-mobile Autonomous Rapidly Relocatable Integrated Electro-optical Resources (HARRIER) with the goal being to design and demonstrate tracking of resident space objects (RSOs) in near-geosynchronous orbit (GEO) using a rapidly-constructed low-cost ground based electro-optic (EO) sensor wit ...

    STTR Phase II 2017 Department of DefenseAir Force
  10. Development of a new small molecule therapeutic for the treatment of resistant breast cancer

    SBC: VioMedix, LLC            Topic: 102

    PROJECT SUMMARYABSTRACTBreast cancer is the second leading cause of death in females with cancerInapproximatelynew cases of invasive breast cancer were diagnosedwhere an estimate ofwas expected to succumb to their diseaseIt is estimated that one in eight women will develop breast cancer in their lifetimeBreast cancer is classified into subtypes based on the expression of estrogen receptorERprogest ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
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