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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Novel Strategy to Identify Substances that Improve Mitochnodrial Fitness

    SBC: CYTEGEN CORP            Topic: NIA

    Project Summary Abstract Mitochondrial dysfunction causes mitochondrial diseases and is tightly linked to aging and neurodegenerative disorders such as Parkinsonandapos s and Alzheimerandapos s Recent discoveries support that mitochondrial dysfunction can be overcome to treat age related decline Cytegenandapos s hypothesis is that exercise induces the secretion of blood borne proteins that act ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Highly sensitive isothermal method and instrument for field diagnostics to facilitate malaria eradication

    SBC: CASCADE BIOSYSTEMS, INC.            Topic: NIAID

    Plasmodium falciparum is the most virulent form of malaria causing million deaths per year Success with patient treatment and a malaria eradication campaign depends significantly on our ability to detect new infections as early as possible in the field rural areas including asymptomatic cases preferably using a small amount of blood e g from a finger prick and to clearly discrim ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. A cloud based software platform to enhance reproducibility collaboration and translation of stem cell research

    SBC: Cellara, LLC            Topic: 400

    Project Summary Stem cell research has shown great potential to help treat or even cure a wide array of health conditions including cardiovascular and neurological disease cancer and diabetes This field is now beginning to move rapidly from the re search stage to clinical translation and commercial applications However it has been widely recognized that stem cell scientists have difficulty ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Graphene based Nanosensor Device for Rapid Onsite Detection of Dissolved Lead in Tap Water

    SBC: NANOAFFIX SCIENCE LLC            Topic: NIEHS

    PROJECT SUMMARY There is an increasing public concern about monitoring water quality in the entire drinking water supply system especially at the point of use spurred by recent water catastrophes such as the one in Flint Michigan that has caused severe health issues for thousands of children due to the unsafe level of lead in contaminated drinking water Current quantitative detection methods ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Bayesian Inference of Spacecraft Geometry and Pose

    SBC: VISION SYSTEMS INC            Topic: AF17AT007

    Space platforms are complex dynamical systems and there are many reasons to model them from ground telescope imagery as well as from space-based sensor platforms. One key motivation is to determine the operational state and configuration of the vehicle. Key questions such as did the solar panels fail to deploy, did the object begin to tumble unexpectedly may be addressed by a sufficiently detaile ...

    STTR Phase I 2017 Department of DefenseAir Force
  6. Rapid Development of Thermodynamic Capability for Integrated Computational Materials Engineering

    SBC: Computherm, LLC            Topic: AF15AT30

    ABSTRACT: CompuTherm, LLC proposes a pilot project to develop an innovative modeling tool for rapid deployment of thermodynamic capability for Integrated Computational Materials Engineering (ICME). To be developed on the basis of CompuTherms current capability, Pandat software, the proposed modeling tool represents the next generation of CALPHAD software. The significant advances of the proposed m ...

    STTR Phase I 2015 Department of DefenseAir Force
  7. Integrated biochemical and bioinformatic technologies for accurate transcriptome-wide full-length RNA assembly.

    SBC: LUCIGEN CORPORATION            Topic: 172

    DESCRIPTION provided by applicant The human transcriptome is significantly more complex than its cognate genome due to the hundreds of thousands of possible isoforms allele specific expression issues variable RNA editing changes and differential expression patterns spanning cell types developmental stages and physiological stresses Next generation sequencing NGS platforms are fundame ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  8. Biological treatment of bacterial keratitis

    SBC: AMEBAGONE INC            Topic: N

    DESCRIPTION provided by applicant Staphylococcus is the most common cause of infections worldwide The pathogen persists asymptomatically on human skin from which it may spread to ocular tissues and cause corneal infection When this happens corneal bacterial keratitis can occur and if not treated effectively it may lead to blindness Multi Drug Resistant MDR variants of S aureus Sa are ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Axonal Transport HTS Platform for Neurodegeneration Drug Discovery

    SBC: Bellbrook Labs, LLC            Topic: 106

    DESCRIPTION provided by applicant Neurodegenerative diseases that affect motor neurons such as PD ALS and HD represent an enormous unmet medical need that is growing with the aging population Existing treatments have little or no effect on the course of disease and patients have to cope with the loss of brain and body function for the rest of their lives Defects in the transport of organell ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Restimulating memory T cell responses in elderly by a novel, live influenza vaccine

    SBC: FLUGEN INC            Topic: NIAID

    DESCRIPTION provided by applicant Respiratory infections with influenza viruses cause severe morbidity and mortality in humans and animals worldwide Importantly in humans the majority of morbidity and mortality following flu infection is seen in older individuals andgt year old Yet clear understanding of how aging impacts on innate immune responses and how to improve vaccine design ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
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