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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Developing a small peptide to control autoimmune inflammation in type diabetes
SBC: Op-T-Mune, Inc Topic: NIAIDAbstract Type Diabetes T D affects an ever growing population While this disease typically has been associated with juveniles the disease in adult populations is rapidly increasing The defining clinical component is insulin loss which occurs because of sustained inflammation in the islets At present there is no means to prevent or reverse insulin loss A major inflammatory pathway in T D ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Restimulating memory T cell responses in elderly by a novel, live influenza vaccine
SBC: FLUGEN INC Topic: NIAIDRespiratory infections with influenza viruses cause severe morbidity and mortality in humans and animals worldwideImportantlyin humansthe majority of morbidity and mortality following flu infection is seen in older individualsrtyears oldYetclear understanding of how aging impacts on innate immune responsesand how to improve vaccine design in this age group is lackingRestimulating preexisting memor ...
STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health -
A Novel Strategy to Identify Substances that Improve Mitochnodrial Fitness
SBC: CYTEGEN CORP Topic: NIAProject Summary Abstract Mitochondrial dysfunction causes mitochondrial diseases and is tightly linked to aging and neurodegenerative disorders such as Parkinsonandapos s and Alzheimerandapos s Recent discoveries support that mitochondrial dysfunction can be overcome to treat age related decline Cytegenandapos s hypothesis is that exercise induces the secretion of blood borne proteins that act ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
E training of Inmate Peer Caregivers for Enhancing Geriatric and End of life Care in Prisons
SBC: KLEIN BUENDEL, INC. Topic: NIAThe US has the highest incarceration rate in the world imprisoning people per The older adult segment of the prison population has more than tripled since and their health issues are common to free people who are years their senior Inmates over the age of have a death rate that is times that of prisoners aged US prison systems are facing sharply increased dema ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Screening for the autoimmune component of multiple sclerosis
SBC: Op-T-Mune, Inc Topic: NIAIDMultiple Sclerosis is an inflammatory neurodegenerative disease with autoimmune components that exacerbate and potentially initiate the disease Diagnosis is invasive time consuming relatively expensive and extremely difficult In fact no clear diagnostic test yet exist A major concern is that MS symptoms are identical to the symptoms of numerous other neurologic diseases OND as well as some ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Highly sensitive isothermal method and instrument for field diagnostics to facilitate malaria eradication
SBC: CASCADE BIOSYSTEMS, INC. Topic: NIAIDPlasmodium falciparum is the most virulent form of malaria causing million deaths per year Success with patient treatment and a malaria eradication campaign depends significantly on our ability to detect new infections as early as possible in the field rural areas including asymptomatic cases preferably using a small amount of blood e g from a finger prick and to clearly discrim ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
A cloud based software platform to enhance reproducibility collaboration and translation of stem cell research
SBC: Cellara, LLC Topic: 400Project Summary Stem cell research has shown great potential to help treat or even cure a wide array of health conditions including cardiovascular and neurological disease cancer and diabetes This field is now beginning to move rapidly from the re search stage to clinical translation and commercial applications However it has been widely recognized that stem cell scientists have difficulty ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Designing and Evaluating Outcome Assessment Software for Youth with Developmental Disabilities: The Pediatric Evaluation of Disability Inventory- Patient Reported Outcome (PEDI-PRO)
SBC: ABLELINK TECHNOLOGIES INC Topic: NICHDChildren and youth with developmental disabilitiesDDreceive extensive pediatric rehabilitation services to address functional limitations in self caremobilityand socializationThe Patient Protection and Affordable Care Act mandates the inclusion of the patient s perspective in healthcare evaluationYetthere is a lack of self reported healthcare assessments appropriate for youth with DDTo accurately ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Non invasive risk assessment tool for pediatric heart failure
SBC: CORAMIR BIOMEDICAL, INC. Topic: NHLBIABSTRACT Heart Failure HF in pediatric patients is a devastating disease that is difficult to evaluate even with invasive hospital procedures Importantly and unique to the pediatric population approximately of pediatric HF patients spontaneously recover normal heart function within year of diagnosis Unfortunately there is no reliable clinical parameter or biomarker that allows pedia ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Novel HDAC Inhibitors for Treatment of Hemoglobinopathies
SBC: CETYA THERAPEUTICS, INC. Topic: NHLBIProject Summary Induction of normal but developmentally silenced fetal globin expression reduces anemia and ameliorates clinical severity in the beta hemoglobinopathies HDACs and are components of the NURD repressor complex which promotes silencing of fetal globin in adult cells Prior generation HDAC inhibitors have increased fetal globin in patients but had limitations for pharmaceu ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health