Award Data

Chronic musculoskeletal pain creates a significant public health burden, and Veterans are disproportionately affected. The frequency and extent of co-occurrence of pain and PTSD, pain and Traumatic Brain Injury (TBI), all three conditions (Post-deployment Multi-symptom Disorder (PMD), and other multi-symptom syndromes can complicate and reduce the effectiveness of pain treatment. Furthermore, the ...

Project Summary The overall goal of this project is to develop our new stable isotope labeledversion of an existing tuberculosisTBdrugisoniazidINHfor use in treated drug resistant TBWe hypothesize that our that isotope enhanced compound can be developed into a powerful new drug against INH resistant TB and multidrug resistant TBby addressing the following specific aimsSpecific AimDetermine what ot ...

ATA proposes to develop an optical communications terminal with low SWaP-C that enables high data rate communications between GPS satellites. Our proposed Laser Communications Crosslink (LaserComXL) terminal integrates advanced ATA line-of-sight stabilization, tracking and pointing technologies with space-qualified laser and detector technologies into a compact package with multiple optical heads ...

Scene generators are commonly used to create synthetic images of ground targets, such as tanks and battlefield wheeled vehicles, to facilitate seeker algorithm development.These scene generators can produce realistic output for sensor types such as infrared or radar, but are limited by the quality of the target models.Typically, the target models show little or no variation so that the seeker algo ...

Vibrant proposes the application of Process Compensated Resonance Testing (PCRT) as an alternative to magnetic particle testing (MT) and penetrant testing (PT) for in-service aircraft wheel and bolt inspection. PCRT collects and analyzes a parts resonance frequencies to perform PASS/FAIL NDI, population characterization, outlier screening and part-to-itself inspection for critical aerospace compon ...

ABSTRACT:MZA partnered with the University of Notre Dame proposes advancement of aero-optical isolation hardware, data processing, and optical modeling for upgrade of AEDCs 16T wind tunnel. We will conduct testing at AEDC during Year 1 with mechanical diagnostics and an upgraded optical sensor with small-aperture access to the test section from outside the 16T pressure vessel. We will also design ...

ABSTRACT SignificanceGravesdiseaseGDone of the most prevalent autoimmune diseasesis caused by stimulating autoantibodiesTSAbto the Thyroid Stimulating Hormone ReceptorTSHRresulting in hyperthyroidismCurrent methods for managing hyperthyroidism in GD target excess thyroid hormone secretion by ablation or removal of the thyroid or by blocking thyroid hormone synthesisEach of these therapies is assoc ...

Neonatal hypoxia ischemiaHIremains a major cause of acute perinatal brain injuryleading ultimately to neurologic dysfunction manifesting as cerebral palsymental retardationand epilepsyUnfortunatelycurrent treatment and prevention strategies in newborns are limitedThere are no currently available therapies to prevent treat and or attenuate brain damage in premature infants other than supportive car ...

ABSTRACT: Space Situational Awareness is concerned with the physical characteristics, capabilities, operations, health, and potential threats posed by space objects. This information is gathered largely via radar and optical data collection facilities. Due to the increasingly large number of space objects and relatively limited number of collection facilities, it's important that collection operat ...

With computer-based systems becoming ubiquitous in all aspects of civilian and military hardware, weaponized high power microwave (HPM) sources pose a danger to the U.S. defense, logistic, and economic infrastructure. Of particular concern is the reliability and survivability of U.S. military aerial assets in the presence of intentional electromagnetic interference (IEMI) from HPM sources.A compre ...