Award Data

ABSTRACT The proposed intervention Culturally Responsible Stress Reduction A Mobile Mindfulness Application to Support Health Promotion for African Americans CRSR is designed to encourage the use of mindfulness to mitigate the disproportionate amount of stress related health disparities facing African Americans Current mindfulness approaches have been unsuccessful in engaging this popula ...

PROJECT SUMMARY ABSTRACT STEM Familia A language acquisition mobile app to improve long term educational and health outcomes among Latino families Enhancing the STEM science technology engineering and math proficiency of Hispanic elementary students to prepare them for success in secondary school and college STEM courses and in STEM fields after graduation While STEM fields account for mo ...

Personal behaviors during pregnancy influence gestational weight gain gestational diabetes mellitus and preeclampsia in addition to developmental programming of the offspring This application is designed to assess the technical merit feasibility usability and potential commercial application of a digital platform and wellness curriculum to reduce the health risks of the mother and child durin ...

Project Summary Systemic sclerosis SSc is a systemic autoimmune disease that results in widespread fibrosis of the skin and internal organs vascular dropout and autoantibody formation SSc has the highest case fatality rate of any systemic autoimmune disease and there remain for FDA approved therapies Analysis of gene expression data on samples collected from SSc patients strongly indicates th ...

Integrative approaches have been found to reduce suffering and improve quality of life in palliative care PC populations and are increasingly in demand by patients and their families However there remains a lack of comprehensive interprofessional easily accessible continuing education continuing medical education CE CME on their evidence based use in PC contexts Objective This FastTrack ...

Multiple myeloma is incurable hematologic malignancy with an expected median survival of years The proteasome inhibitors bortezomib carfilzomib and the recently approved ixazomib are a mainstay of current myeloma treatment Despite an initial response rate approaching to proteasome inhibitor containing combinations all patients relapse and eventually become resistant to any treatments ...

Approximately one out of three to year old children in the United States has experienced caries tooth decay The American Academy of Pediatric Dentistry and American Academy of Pediatrics provide recommendations for preventive strategies and recognize that infant toddler and early childhood oral health is one of the foundations upon which preventive education and dental care must be built ...

ABSTRACT SignificanceGravesdiseaseGDone of the most prevalent autoimmune diseasesis caused by stimulating autoantibodiesTSAbto the Thyroid Stimulating Hormone ReceptorTSHRresulting in hyperthyroidismCurrent methods for managing hyperthyroidism in GD target excess thyroid hormone secretion by ablation or removal of the thyroid or by blocking thyroid hormone synthesisEach of these therapies is assoc ...

This revised Phase I SBIR proposal aims at developing a topical formulation of siRNA nanoparticle that delivers siRNA to treat skin fibrosis Our platform has inherent antioxidant and anti inflammatory properties further benefitting the treatment of skin fibrosis for which there is no effective treatment Upon completion the platform will have broad applicability since siRNA can be designed to k ...

Abstract Project Summary Scleroderma Systemic Sclerosis SSc is an autoimmune disease of unknown etiology that is characterized by vascular dysfunction fibrosis and inflammation One in three patients dies within years of diagnosis giving SSc the highest case fatality rate of any systemic autoimmune disease A lack of biologically relevant human SSc disease models has created a critical ...