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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Telehealth Intervention for Improved Blood Pressure Control with Targeted Incentives Using New Technologies and Insights From Behavioral Economics to Increase the Effectiveness of Behavioral Change

    SBC: Wellth Inc.            Topic: NIA

    PROJECT SUMMARY ABSTRACT Hypertension or sustained systolic and diastolic blood pressure BP of and mm Hg or higher is among the most frequently encountered conditions in primary care in the U S The estimated prevalence is among all U S adults and increases with age to affect of seniors Hypertension is also the leading risk factor for cardiovascular disease global mortality ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Isolation and characterization of a primary breast epithelium transforming agent

    SBC: SkinAxis LLC            Topic: 102

    Abstract Breast cancer BC is the most common cancer among women Viruses have long been suspected as a cause of breast cancer However despite the identification of virions in human BC cells and human milk and numerous studies that suggest possible connection between breast cancer and Epstein Barr virus EBV mouse mammary tumor virus MMTV and human papilloma virus HPV the tumorigenic po ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Novel Antigen-Specific Immunomodulatory Tregitope-based Therapy to Address Autoimmune Pathogenesis in Graves' Disease

    SBC: EPIVAX, INC.            Topic: 200

    ABSTRACT SignificanceGravesdiseaseGDone of the most prevalent autoimmune diseasesis caused by stimulating autoantibodiesTSAbto the Thyroid Stimulating Hormone ReceptorTSHRresulting in hyperthyroidismCurrent methods for managing hyperthyroidism in GD target excess thyroid hormone secretion by ablation or removal of the thyroid or by blocking thyroid hormone synthesisEach of these therapies is assoc ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. A practical and versatile high resolution D dosimetry system for clinical use

    SBC: HEURIS INC.            Topic: 102

    Quality assurance QA is a critical component of radiation oncology that ensures both effective treatment delivery and patient safety Over the last decade dQA is now particularly important asramatic innovations in treatment delivery technologiesy have led to increasingly sophisticated and complex treatments that are difficult to adequately verify with conventional dosimetric verification system ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. An Improved Method of Delivering a Sclerosing Agent for the Treatment of a Malignant Pleural Effusion

    SBC: TDL INNOVATIONS LLC            Topic: 102

    Project Summary We are developing an improved clinical method to treat patients with malignant pleural effusions A pleural effusion is an abnormal build up of fluid in the pleural cavity the fluid space that surrounds the lungs These malignant pleural effusions MPE occur in patients in the US each year affecting between to of all cancer patients Management of a MPE is p ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Method for High Throughput Assembly of Long DNA Fragments in vitro

    SBC: Pharmaseq, Inc            Topic: 200

    SUMMARY The main project goal is to develop principles and demonstrate the feasibility of a fast in vitro method that will increase the length of synthetic double stranded DNA from its current limit of about kb to kb This in turn will facilitate the ability to more rapidly create artificial genes and chromosomes and thus become an important tool in synthetic biology The proposed approac ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Small Molecule Therapy for the Treatment of Heart Failure

    SBC: SUMOCOR LLC            Topic: NHLBI

    ABSTRACT The incidence of heart failure HF continues to increase in the United States despite significant advances in pharmacological therapies and novel devices There is an acute need for novel treatment strategies for heart failure A key abnormality in HF is defective handling of calcium that has been partially related to abnormal sarcoplasmic reticulum SR function in cardiac myocytes Red ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Development of a novel combination of anti-septic taurolidine encased in a digestible nanoparticle system for use as topical treatment at burn sites

    SBC: CorMedix Inc.            Topic: 300

    ABSTRACT Burn injury care has improved in the past decadesbut complications still occur and lead to prolonged hospital stays and potentially to deathThe risk of infection rises as a result of burns since the skin layerswhich function as a barrier and prevent pathogens from accessing the susceptible body tissuesare no longer intactImportantlyinfections involving gram negative or gram positive patho ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. EVVS Endoscopic Venous Valve System

    SBC: VENARUM MEDICAL LLC            Topic: NHLBI

    Project Summary Abstract Venarum Medical LLC Venarum proposes to validate the Endoscopic Venous Valve System EVVS a novel patent pending valve replacement solution for serious complications of chronic venous disease CVD such as chronic venous insufficiency CVI and specifically dysfunctional venous valves This device is based on the principle that a nitinol stent like scaffold embe ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Enhancing Systems Engineering for Complex Systems with Digital Thread

    SBC: PRAESES, LLC            Topic: AF171114

    As the size, scope, and complexity of interoperable systems increase, so do the systems engineering challenges of understanding and managing them. A System of Systems (SoS) is a collection of pooled resources, capabilities, and subsystems used to create a

    SBIR Phase I 2017 Department of DefenseAir Force
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