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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Reducing Hypertension among African American Men: A Mobile Stress Management Intervention to Address Health Disparities

    SBC: ISA ASSOCIATES INC            Topic: NIMHD

    PROJECT SUMMARY/ABSTRACTAfrican American men have the highest rate of hypertension (HTN) in the United States. Once diagnosed, they are also less likely to achieve blood pressure (BP) control. This health disparity is critical, as elevated BP is the primary modifiable risk factor for cardiovascular disease. One reason for this HTN disparity: stress. African Americans report more stress than their ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  2. An Interactive Education Program to Reduce High Risk Behavior in Adolescents

    SBC: KLEIN BUENDEL, INC.            Topic: NICHD

    Internet-based TRAC (i-TRAC): Interactive Emotion Regulation Skills Training to Improve AdolescentSexual Health Adolescence is a critical developmental period during which behavioral patterns are formed that have powerful influences on current and future health. This is particularly true for sexual behavior, which is affected by the biological changes of puberty as well as normative developmental ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  3. Improving Maternal Outcomes of Cesarean Delivery with the Prevention of Postoperative Adhesions

    SBC: LUNA LABS USA LLC            Topic: NICHD

    ABSTRACT An increased incidence of various pre-existing conditions like diabetes and hypertension, combined with systemic issues surrounding the quality of maternal health care provided, has resulted in a significant increase in the cesarean delivery rate in minority communities. These surgical procedures contribute to disparities in maternal health outcomes and postoperative complications, as C-s ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  4. Pre-Clinical Assessment of a Minimally Invasive Meniscus Implant to Delay Arthritis

    SBC: ORTHOPRESERVE LLC            Topic: NIAMS

    Abstract Meniscus tears are among the most common orthopedic injuries, with about 1 million occurring in the United States each year and growing at a rate of 5% annually. Shortcomings associated with the current standard of care leaves a clinical need for a new treatment option. The meniscal tissue can only be repaired in limited cases due to its healing capacity, so the most common treatment for ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  5. A First-in-class Topical Immunoregulatory Therapeutic for Psoriasis

    SBC: Biotherapeutics, Inc.            Topic: NIAMS

    A First-in-class Topical Immunoregulatory Therapeutic for Psoriasis BioTherapeutics Inc (BTI) is an emerging biotech company that synergistically combines the power of advanced computational modeling with translational experimentation to accelerate the development of novel product candidates for precision immunology. An unmet clinical need for safer, more effective drugs for plaque psoriasis remai ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  6. Inter-alpha Inhibitors in Experimental Necrotizing Enterocolitis

    SBC: PROTHERA BIOLOGICS, INC.            Topic: NICHD

    Necrotizing enterocolitis (NEC) is a devastating acute inflammatory condition of the gastrointestinal tract resulting in intestinal necrosis, systemic sepsis and multi-system organ failure found mostly in infants born prematurely. Despite modern medical advances in the past decade, the etiology remains elusive and morbidity and mortality are still unacceptably high. It has been concluded that the ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  7. Feasibility of app-delivered circadian synchronization therapy with light in a cohort of pregnant women

    SBC: ARCASCOPE INC.            Topic: NICHD

    PROJECT SUMMARY Circadian rhythms play a vital role in promoting maternal health and managing pregnancy outcomes, including gestational diabetes, preterm birth, and postpartum depression. However, interventions to mitigate circadian rhythms disruption during pregnancy are lacking, despite readily available non-pharmacological circadian interventions. The circadian timekeeping system is strengthene ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  8. Access-H20: Sensor driven smart faucet to enable and empower independent drinking and grooming for individuals impacted by spinal cord injury

    SBC: NASONI, LLC            Topic: NICHD

    SCI incidence ranges from 250k-500k globally/year, with rt7M people impacted. Currently rt300k U.S. individuals live with SCI. SCI results in life-altering consequences in terms of morbidity, mortality, functional status, employment, and quality of life. For quadriplegics with cervical injuries, even basic ADLs are severely compromised. Individuals learn assistive strategies for ADLs such as eatin ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  9. Live spike sorting for multichannel and high-channel recordings

    SBC: POPNEURON LLC            Topic: 106

    Project Summary: The goal of this project is to create two prototypes of a novel live spike sorting system which can be used by investigators to spike sort streams of neural data recorded by multi-channel, high channel and ultra-high channel probes. In most in-vivo extracellular recording conditions, an electrode can pick up neural spikes from several nearby neurons resulting in so-called “multi ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  10. Inter-alpha Inhibitors in Hypoxic-Ischemic Brain Injury

    SBC: PROTHERA BIOLOGICS, INC.            Topic: 105

    Perinatal brain injury resulting in mental retardation and cerebral palsy is the most severe disability in children and affects 40-148 in preterm and 1–2/1000 in full term infants. This places a huge burden on society, emphasizing the critical need for improved prevention/treatment strategies to decrease perinatal brain injury. Hypothermia (HT) is the only FDA approved therapy to attenuate brain ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
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