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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. TOKAMAK PLASMAS

    SBC: Kms Fusion Inc            Topic: N/A

    INJECTION OF SOLID FUEL PELLETS INTO A TOKAMAK REACTOR IS ANATTRACTIVE TECHNIQUE FOR REFUELING. THE CONCEPT IS BASED ONTHE UNIFORM EVAPORATION OF THE CRYOGENIC MATERIAL DURING ITSTRAVEL ACROSS THE MINOR DIAMETER OF THE MACHINE. THE ABLATION RATE IS DETERMINED BY THE PHYSICS OF THE HEAT CONDUCTION FROM THE LOW-DENSITY, HIGH-TEMPERATURE TOKAMAK PLASMA. THE INJECTION VELOCITY REQUIRED IS DETERMINED B ...

    SBIR Phase I 1983 Department of Energy
  2. Responsible Drinking: Internet-based, Interactive Computer Tailored Intervention

    SBC: Pro-Change Behavior Systems, Inc.            Topic: NIAAA

    DESCRIPTION (provided by applicant): Excessive alcohol use is associated with a range of serious and costly health, social, and economic consequences at the individual and societal level. This program of research serves as a venue by which to produce and test an innovative, science-based, and cost-effective means to intervene in a private, convenient, and individualized way with employed adults wh ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  3. Computerized Stage-Matched Intervention for Juvenile Offenders

    SBC: Pro-Change Behavior Systems, Inc.            Topic: NIDA

    DESCRIPTION (provided by applicant): Juvenile crime imposes enormous costs on victims, on society, and on juvenile offenders themselves. However, research assessing the efficacy of interventions for young offenders show, on average, only small effects on recidivism, substance abuse, and other behavioral outcomes. A major problem with existing interventions is that they tend to neglect individual d ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  4. EpiVax Phase II SBIR: Preclinical studies of Tregitope Delivery and Mechanism of

    SBC: EPIVAX, INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): The goal of this Phase II project is to advance the development of novel tolerance-inducing peptides (Tregitopes) to prevent and/or treat Type 1 diabetes (T1D) by optimizing the clinical delivery vehicle and treatment protocol, and by identifying correlates of efficacy in preparation for Phase 1 clinical trials. More than 13,000 children in the U.S. are diagnos ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  5. NOVEL HIGH THROUGHPUT PLATFORM FOR SCREENING CYTOCHROME P450 INDUCTION

    SBC: ORIGINUS, INC.            Topic: NIEHS

    DESCRIPTION (provided by applicant): Many prescribed drugs exhibit drug-drug interactions due to up-regulation or inhibition of specific P450 enzymes. According to a recent guidance from the FDA, CYP1A2, CYP2B6, and CYP3A4 induction should be evaluated inat least an in vitro system. Enzymatic activity in freshly isolated hepatocytes is the Gold Standard for studying P450 induction; however, it ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  6. An Antisense Design and Simulation Platform

    SBC: DNA SOFTWARE, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): In this grant proposal An Automated Antisense Design and Simulation Platform , a comprehensive molecular diagnostics software tool that is specific to the design and simulation of antisense oligonucleotide analog probes will be developed. The application of antisense technologies to the study of human diseases has been proven in the literature for cancer, im ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  7. Novel Micro-Implant to Measure Intracardiac Pressure in Congenital Heart Patients

    SBC: Integrated Sensing Systems Incorporated            Topic: NHLBI

    DESCRIPTION (provided by applicant): Congenital heart disease patients with functional single ventricle (FSV) anatomy usually require a series of surgeries during infancy and childhood in order to provide them with a chance to survive into adulthood. The second stage surgery, termed the hemi-Fontan procedure (HFP) re-routes systemic venous blood from the upper body and head into the pulmonary circ ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  8. Selective Cytopheresis Therapy in Systemic Inflammatory Response Syndrome

    SBC: Innovative Biotherapies, Inc.            Topic: NCATS

    DESCRIPTION (provided by applicant): Leukocytes (LE) are major contributors to the pathogenesis and progression of many clinical inflammatory disorders, including the systemic inflammatory response syndrome, sepsis and acute respiratory distress syndrome.The need for new and innovative therapies to treat these inflammatory disease states presents a large commercial market opportunity. A large numb ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  9. Improved TTHM Reduction Processing and Operational Efficiencies in Potable Water Distributions Systems Using Solar-Powered Circulation with Diffused, Near-Surface Aeration

    SBC: SolarBee, Inc.            Topic: A

    The U.S. EPA Stage 2 Disinfectants and Disinfection Byproducts Rule (S2DDBR) requires potable water utilities to maintain total trihalomethane (TTHM) concentrations below 80µg/L at all locations within distribution systems beginning in 2012 due to adverse health-effect risks. Air stripping effectively volatilizes TTHMs due to their low Henry’s law constants. However, commercially available ai ...

    SBIR Phase I 2012 Environmental Protection Agency
  10. Fiber-laser Array Pumped OPCPA Laser-Plasma Accelerator Driver

    SBC: Arbor Photonics, Inc.            Topic: 66d

    So-called tabletop accelerators are a holy-grail of high energy/high field physics and, if developed, as indicated by the Department of Energy in the Accelerators for America report, will spur a revolution in particle physics discoveries and also in medical treatments. This is because planned next-generation particle accelerators are still kilometers in size and billions of dollars to build and su ...

    SBIR Phase II 2012 Department of Energy
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