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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Automated Survey Instrument Documentation, Analysis

    SBC: ALGENTA TECHNOLOGIES LLC            Topic: N/A

    This Small Business Innovation Research Phase I project will develop technology to automate the creation of survey instrument documentation, to analyze the complexity of survey instruments, and to automate the testing of survey instruments. Software that enables researchers to better visualize, analyze, and test survey instruments will result in higher quality survey data and increased producti ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  2. Development of novel proteins as a defence against potential biothreat agents

    SBC: ALPHA UNIVERSE LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The ongoing war on terror has created the necessity of a whole new spectrum of systems that are able to detect and inactivate biothreat agents, systems that are inexpensive to produce, robust and stable to allow their use on a massive scale by first responders or even the general population. However, properties of antibodies that are currently used as main comp ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  3. Probes and cell arrays for detection of bacterial toxins

    SBC: ALPHA UNIVERSE LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Microarray technology offers an opportunity for simultaneous monitoring of the behavior of multiple markers within a mammalian cell and ultimately could be used for detection and elucidation of mechanisms of action of different biologically active agents, including those that are considered a threat in the biodefense area. The "predictive power" of probes used ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  4. Intracranial Brain Function Mapping System

    SBC: CHATTEN ASSOC., INC.            Topic: N/A

    DESCRIPTION (provided by applicant): We will develop a modern, computer-controlled electrical stimulator for performing functional mapping by cortical stimulation. The primary application is for use with patients who are candidates for surgery to control or eliminate occurrence of epileptic seizures. Other applications will include functional mapping to plan surgery for other brain diseases such a ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  5. Tools and Technology to Measure Menopausal Symptomatology

    SBC: BAHR MANAGEMENT, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Principal Investigator/Program Director (Last, First, Middle): Webster, John G. 6. Project Summary/Abstract.The major symptoms associated with the menopause transition are hot flashes, trouble sleeping and vaginal dryness or irritation {Nelson, 2005}. Measurement of the frequency and severity of these symptoms has typically relied on self-report by recall over ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  6. Generic Fluorescent HTS Assay for Kinases and ATPases

    SBC: Bellbrook Labs, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): There are over 500 protein kinases in the human genome and several hundred other enzymes that utilize ATP as a phosphate donor or energy source. Protein kinases are the second most intensively screened target class, with links to all of the major therapeutic areas, most notably cancer. Important disease links for cancer and anti-infectives also are emerging for ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  7. Fluorescent HTS Assay for Methyltransferases in Neurodegenerative Diseases

    SBC: Bellbrook Labs, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Methylation is a ubiquitous covalent modification used to control the function of diverse biomolecules including hormones, neurotransmitters, xenobiotics, proteins, nucleic acids and lipids. More than 50 distinct methyltransferase (MTs) enzymes are present in humans, and they are being targeted for a broad range of diseases, but their involvement in neurodegene ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  8. Utilize Cementitious High Carbon Fly Ash (CHCFA) to Stabilize Cold In-Place Recycled (CIR) Asphalt Pavement as Base Course

    SBC: Bloom Consultants, LLC            Topic: 11

    Because of stringent environmental regulations, the power generation industry must take measures to reduce the emission of nitrogen oxides (NOx), sulfur oxides (Sox), and mercury (Hg). Low-NOx burners reduce emissions by changing the combustion characteristics of coal boilers, but they increase the amount of residual unburned carbon in the fly ash. Increased carbon levels in fly ash make air-ent ...

    STTR Phase II 2006 Department of Energy
  9. Increased production of protein from senescent cells

    SBC: CLONEX DEVELOPMENT, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Most commercial therapeutic proteins, such as monoclonal antibodies (Mabs), are produced from traditional hybridoma cultures or genetically engineered Chinese hamster ovary (CHO) cells using large scale : bioreactors. Bioprocessing of therapeutic proteins is exceedingly expensive because of the high costs of , building and maintaining FDA-approved facilities, c ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  10. Plastic Oil Bottle Recycling

    SBC: CRI Recycling Services, Inc.            Topic: N/A

    Various oily wastes are generated while performing vehicle maintenance operations, including used oil drained from the engine, the oil filter, and even oil absorbent the is used to clean up oil that has spilled on the floor. At one time these wastes were placed in landfills. Concerns with oil from these waste migrating into surface and ground water has prompted a number state and federal regulat ...

    SBIR Phase I 2006 Environmental Protection Agency
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