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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Development of RLIP76 protein as a Radiation Countermeasure

    SBC: TERAPIO            Topic: NIAID

    DESCRIPTION (provided by applicant): There remains a critical need for medicines that can counteract the toxic effects of radiation exposure. Terapio is developing a recombinant protein, RLIP76, for use as a radioprotectant for workers, military personnel, or civilians that are either in imminent danger of radiation exposure, or have already been exposed. In research carried out at the Unive ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  2. Evaluation and Production of a Multivalent Adenoviral Plague Vaccine

    SBC: NORWELL, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): The final objective of this Phase II SBIR is to complete preclinical studies of a trivalent adenoviral vaccine against plague in preparation for human clinical trials. The plague vaccine project was selected in responseto the growing concern surrounding the organism's possible use in a terrorism event. The NIAID and CDC, in response to this threat, has cla ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  3. TP508: A New Drug for Mitigating Lethal Effects of Radiatin Exposure

    SBC: Chrysalis BioTherapeutics, Inc.            Topic: NIAID

    DESCRIPTION (provided by applicant): With recent radiation release from reactors in Japan and increasing probability of nuclear detonation somewhere in the world, there is a critical need for development of effective medicinal counter-measures that can bedelivered after exposure to prevent radiation-induced mortality. Adding to this need, mortality increases significantly when radiation is combine ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  4. Targeted Neural Plasticity for the Treatment of Tinnitus

    SBC: MICROTRANSPONDER, INC.            Topic: NIDCD

    DESCRIPTION (provided by applicant): This is a proposal to conduct a multi-center, double-blind, sham-controlled partial cross-over interventional study to test safety and efficacy of our novel tinnitus therapy. The tinnitus field generally accepts that elevated synchronous spontaneous activity in the auditory cortex may account for the tinnitus percept that arises following hearing loss. Followin ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  5. Sutureless Laparoscopic Partial Nephrectomy Using Laser Tissue Welding: Preclinic

    SBC: Laser Tissue Welding, Inc            Topic: NIDDK

    DESCRIPTION (provided by applicant): Preservation of functioning renal parenchyma is important and nephron-sparing surgery substitutes for radical nephrectomy in appropriately selected patients with renal cell carcinoma. Laparoscopic partial nephrectomy (LPN) has demonstrated excellent outcomes in terms of oncologic control, but is under-used due to major technical challenges of parenchymal hemost ...

    SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  6. Computerized Stage-Matched Intervention for Juvenile Offenders

    SBC: Pro-Change Behavior Systems, Inc.            Topic: NIDA

    DESCRIPTION (provided by applicant): Juvenile crime imposes enormous costs on victims, on society, and on juvenile offenders themselves. However, research assessing the efficacy of interventions for young offenders show, on average, only small effects on recidivism, substance abuse, and other behavioral outcomes. A major problem with existing interventions is that they tend to neglect individual d ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  7. EpiVax Phase II SBIR: Preclinical studies of Tregitope Delivery and Mechanism of

    SBC: EPIVAX, INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): The goal of this Phase II project is to advance the development of novel tolerance-inducing peptides (Tregitopes) to prevent and/or treat Type 1 diabetes (T1D) by optimizing the clinical delivery vehicle and treatment protocol, and by identifying correlates of efficacy in preparation for Phase 1 clinical trials. More than 13,000 children in the U.S. are diagnos ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  8. IMPLANTABLE BATTERYLESS PACEMAKER AND TELEMETRY DEVICE FOR SMALL ANIMALS

    SBC: INDUS INSTRUMENTS            Topic: NHLBI

    Cardiac arrhythmias are a major public health burden. There are 250,000 - 400,000 sudden cardiac deaths (SCD) in the US every year, accounting for up to 20% of all deaths in adults; the majority of these are due to ventricular fibrillation. In addition, approximately 2.5 million Americans now suffer atrial fibrillation (AF), a number that is expected to surpass 5 million by 2050. Strong evidence i ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  9. Flat Panel X-ray Sources for Digital Breast Tomosynthesis System

    SBC: STELLARRAY INC            Topic: NCI

    DESCRIPTION (provided by applicant): X-ray mammography continues to be the primary tool for breast cancer screening and plays an important role in the diagnosis and management of breast cancer. However, the difficulty in resolving overlapping structures ina 2-D projection image leads to reduced sensitivity. A number of research groups and companies are developing dedicated breast tomographic syste ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  10. GI-Safer Formulation of Indomethacin for use in Preterm Neonates

    SBC: PLx Opco Inc.            Topic: NICHD

    DESCRIPTION (provided by applicant): This application is for a SBIR Phase II grant. One of the major causes of morbidity and mortality of low birth weight neonates relates to injury, inflammation, perforation and obstruction of the lower GI tract, which can be manifest in the related diseases Necrotizing Enterocolitis (NEC) and Spontaneous Intestinal Perforation (SIP). These digestive diseases, wh ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
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