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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Assembled Porous Silica Membranes for Biomolecule SPE

    SBC: ADVANCED MATERIALS TECHNOLOGY, INC.            Topic: 400

    Abstract Life sciences research and other critical bioanalytical applications would strongly benefit from faster and higher efficiency sample preparation processes Sample preparation before high resolution analytical methods such as HPLC or LC MS can require effort and cost nearly equivalent to the actual sample analysis and data reduction Often sample preparation for proteomic glycoproteom ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. A Preclinical Trial of Therapeutic Angiogenesis Plus Angioplasty and Stenting for Renal Vascular Disease

    SBC: LEFLORE TECHNOLOGIES LLC            Topic: 400

    Abstract Chronic kidney disease CKD is a progressive disorder affecting almost of the general population and this disease has shown a relentless growth over the past decades Patients with CKD have higher rates of hospitalization greater mortality shorter life expectancy and their healthcare costs are up to times more expensive than non CKD patients Thus treatments to slow halt ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Developing an integrated sorting and single cell analysis tool for the analysis of rare T Cells subsets in Autoimmunity

    SBC: ISOPLEXIS CORPORATION            Topic: R

    Autoimmune disease AD affects up to million Americans which costs approximately $ billion on health care annually and accounts for one of the leading causes of death in women T cells and cytokine function play an important role in autoimmune diseases such as Type Diabetes Multiple Sclerosis Rheumatoid Arthritis RA and Systemic Lupus Erythematosus SLE The most successful auto i ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Precision quality check of immunotherapeutics via single-cell cytokine mapping

    SBC: ISOPLEXIS CORPORATION            Topic: 102

    Adoptive transfer of autologous T cells engineered to express chimeric antigen receptorsCARshas emerged as a promising immunotherapy for patients with hematologic malignanciessuch as CDCARs in leukemias and lymphomasHoweverchallenges remain in terms of manufacturing consistency and the functional profile of the CAR T cell productsince infused cellsasliving drugscan be activated and release a varie ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Inter-alpha Inhibitors in Hypoxic-Ischemic Brain Injury

    SBC: PROTHERA BIOLOGICS, INC.            Topic: 105

    Neonatal hypoxia ischemiaHIremains a major cause of acute perinatal brain injuryleading ultimately to neurologic dysfunction manifesting as cerebral palsymental retardationand epilepsyUnfortunatelycurrent treatment and prevention strategies in newborns are limitedThere are no currently available therapies to prevent treat and or attenuate brain damage in premature infants other than supportive car ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Enhanced Oxidative Dehydrogenation of Ethane with Facilitated Transport Membranes for Low Cost Production of Ethylene

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: 17a

    Ethylene demand is expected to increase by 50% domestically and worldwide over the next 5 years. Much of this and future growth is likely to be met from shale gas based ethane. Dr. Anne Gaffney of the US-DOE has invented a mixed metal oxide catalyst, M1, for the oxidative dehydrogenation of ethane (C2- ODH) to ethylene at high conversions and very high selectivities. A major hurdle for commercial ...

    SBIR Phase I 2017 Department of Energy
  7. Flux Monitoring on an X-Ray Refractive Diamond Lens

    SBC: Delaware Diamond Knives, Inc            Topic: 05d

    Synchrotron-based science has had a great scientific impact and will continue to have great impact going forward. In spite of the large investment in the 3rd generation light sources, most beam lines do not preserve the source’s phase profile or brightness all the way to the sample. For these high brightness light sources, errors are almost completely due to distortion ...

    SBIR Phase I 2017 Department of Energy
  8. Ion Exchange Materials for Lithium Extraction (Topic: 15, Subtopic: e)

    SBC: Lilac Solutions, Inc.            Topic: 15e

    Electric vehicles are creating unprecedented demand for lithium. Most lithium is produced from brine resources. Conventional methods for extracting lithium from brines suffer from low lithium recovery and cannot access the expanded resources needed for mass adoption of electric vehicles. The Department of Energy has supported a great variety of projects relate ...

    SBIR Phase I 2017 Department of Energy
  9. Integrating Sphere-Based Nephelometer for UAS Applications

    SBC: American Ecotech L.C.            Topic: 17a

    Novel compact and sensitive instruments measuring light scattering from microscopic airborne particles (i.e., aerosols) are needed for deployment on small aerial platforms to characterize aerosol influence on air quality, earth system dynamics, and visibility degradation. The Phase 1 project has developed, modeled, and characterized prototypes of such instruments based on transformative technologi ...

    SBIR Phase II 2017 Department of Energy
  10. Diamond Strip Detectors for Charged Particle Tracking, 24b

    SBC: Applied Diamond, Inc.            Topic: 24b

    Applied Diamond will make large area particle detectors of CVD diamond for use in nuclear physics experiments at DOE and other laboratories. These detectors will reduce the operating expense and increase the capabilities of these facilities accelerating advances in nuclear science.

    SBIR Phase II 2017 Department of Energy
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