Award Data

DESCRIPTION (provided by applicant)The major goals of this revised, SBIR Phase II application for the combined R25/R44 mechanism to complete development of a multi-media, cancer risk behavior modification intervention and to conduct a randomized controlled trial with low income patients and their primary care physicians to assess its impact. The prototype system of tools created in the Phase I is ...

DESCRIPTION (provided by applicant)The major goals of this revised, SBIR Phase II application for the combined R25/R44 mechanism to complete development of a multi-media, cancer risk behavior modification intervention and to conduct a randomized controlled trial with low income patients and their primary care physicians to assess its impact. The prototype system of tools created in the Phase I is ...

DESCRIPTION (Provided by applicant): BCR Diagnostics, Inc. (BCR) proposes to demonstrate the feasibility of adapting its LEXSAS (Label-free Exponential Signal-Amplification System) technology for real-time bacteriologic analysis of blood products intended for transfusion. The LEXSAS technology is unique in that it uses spores as ultrasensitive nanodevices capable of emitting fluorescent light sign ...

DESCRIPTION (provided by applicant): An innovative fluorescence system for sensing biomolecular interactions was developed in Phase I that is based on total internal reflection fluorescence (TIRF). The main advantages of this system are integrated microfluidics and a design that allows rapid replacement of TIRF sensor chip. The feasibility of building a highly sensitive and versatile TIRF biosenso ...

DESCRIPTION (provided by applicant): An innovative fluorescence system for sensing biomolecular interactions was developed in Phase I that is based on total internal reflection fluorescence (TIRF). The main advantages of this system are integrated microfluidics and a design that allows rapid replacement of TIRF sensor chip. The feasibility of building a highly sensitive and versatile TIRF biosenso ...

65445 Consumption of diesel fuel and gasoline have led to significant dependence on foreign fuel as well as increased carbon dioxide emissions with the associated concern for global warming. Diesel engines are much more fuel efficient than spark/gasoline engines, but unfortunately diesel engines produce high NOx emissions. This has been addressed by a process known as exhaust gas recycle (EG ...

65445 Consumption of diesel fuel and gasoline have led to significant dependence on foreign fuel as well as increased carbon dioxide emissions with the associated concern for global warming. Diesel engines are much more fuel efficient than spark/gasoline engines, but unfortunately diesel engines produce high NOx emissions. This has been addressed by a process known as exhaust gas recycle (EG ...

DECRIPTION (Provided by applicant): Pyrogen-free water (PFW) is required in many applications. Laboratories use it as solvent for compound preparation, culture media, and equipment rinse. Hospitals use it for cleaning to prepare solutions for injections, lV's, and hemodialysis. Pharmaceutical manufacturers use it to formulate injectable drug preparations. Pyrogens, or fever-inducers, are derived f ...

A new class of antimicrobials based on dendrimer technology has been identified and shown to possess potent biocidal activity. Laboratory evaluation of these polycationic dendrimers has shown that they are more than 100 times more effective than a comparable amount of free quaternary ammonium compound at killing Esherichia coli. Potent activity against Staphylococcus aureus has also been demonstra ...

DESCRIPTION (provided by applicant): Total Artificial Heart (TAH) and related devices (e.g., ventricular assist device) are emerging that provide the potential for almost unlimited patient mobility and near-normal lifestyle for the patient. The new devices being developed are totally implantable, self-contained (battery is external), electrically driven systems. However, the power and energy densi ...