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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Advancing a Glioma Immunotherapy

    SBC: IN CYTU, INC.            Topic: 102

    DESCRIPTION provided by applicant A Phase II SBIR program of preclinical development is proposed for the development of an active specific immunotherapeutic called Cellariumandquot for treatment of glial cell based cancers Successful completion of this project will confirm therapeutic effect and pre clinical safety of the vaccine in preparation for first in human studies Upon demonstration of ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Novel DFG out inhibitors of Abl-kinases to treat PML

    SBC: Inhibikase Therapeutics, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Inhibikase Therapeutics is a clinical stage biopharmaceutical company that has developed a host targeted mechanism of action to treat AIDS related and drug induced progressive multifocal leukoencephalopathy PML PML is a demyelinating disease of the central nervous system and was rarely seen clinically until the era of the HIV epidemic began in the mid s During the ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  3. MySearch: Purposeful Individual and Independent Activities for Persons with Early to Moderate Stage Alzheimer’s Disease and Related Dementias

    SBC: Linda-&-Cameron, Inc.            Topic: NIA

    DESCRIPTION provided by applicant In the United States today million people are living with Alzheimerandapos s disease AD Alzheimerandapos s Association With increased diagnostic accuracy for detecting AD early stage cases of AD are rapidly growing These individuals especially when placed in residential care settings can present significant behavioral challenges to staff mem ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Development of a Non adjuvanted VLP Vaccine against Stealth H N Influenza

    SBC: EPIVAX, INC.            Topic: NIAID

    DESCRIPTION provided by applicant The avian origin H N influenza virus that emerged in humans in China in presents a unique challenge to vaccine development because it is poorly immunogenic Neutralizing antibodies are not detected in acute phase infection Anti H antibody responses are significantly delayed and exhibit low avidity in comparison with antibodies generated following seas ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Online resource center for older adults with cochlear implants

    SBC: KDH Research & Communication, Inc.            Topic: NIDCD

    In this Phase I proposal resubmission KDH Research andamp Communication KDHRC proposes to develop and evaluate the Online Resource Center for Older Adults with Cochlear Implants RCCI RCCI will be an innovative web based resource center for older adults aged with cochlear implants CIs and their family members for age related hearing loss RCCI will provide high quality information ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Nanotechnology-Based Environmental Smart Sensors for Personal Health Exposure Monitoring

    SBC: WI-SENSE LLC            Topic: NIEHS

    DESCRIPTION provided by applicant A broad goal of the proposed research is to develop personal exposure monitors comprising wearable wireless sensor arrays to detect harmful air pollutants within the breathing zone and improve the assessment of causative exposure dose response relationships in epidemiological studies Heterogeneous orthogonal detectors comprising functionalized carbon nanotub ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Cryopreserved Adherent Neural Cell Assay Plates

    SBC: ARUNA BIO, INC.            Topic: 113

    DESCRIPTION provided by applicant Neural progenitor migration is an important process for the proper development and maintenance of the nervous system Derived from proliferative zones within the brain neural progenitors migrate to specific destinations guided by various extracellular cues Exposure to neurotoxicants during development can interfere with neural progenitor migration and lead to ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Rapid response toxicology prediction platform

    SBC: LEADSCOPE, INC.            Topic: NIEHS

    DESCRIPTION provided by applicant In many situations it is critical to rapidly estimate the safety of new or existing chemicals For example in the event of a sudden unexpected exposure of a chemical such as with a chemical spill or a terrorist attack an emergency response is needed to determine if and how to mitigate any potential risk from the chemicalsandapos toxicity and to monitor thi ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Non-Invasive Intraoral LED Phototherapy Device for the Prevention and Treatment of Oral Mucositis

    SBC: Lumitex, Inc.            Topic: NIDCR

    DESCRIPTION provided by applicant The goal of this SBIR is to create a novel phototherapeutic light delivery device which will advance the standard of care for the prevention and treatment of Oral Mucositis OM OM is one of the most common and highly significant toxicities of cancer therapy Approximately patients are affected by OM in the United States each year OM is an extremely ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. A Method for Quantitatively Retrieving Circulating miRNAs from Plasma

    SBC: GLC Biotechnology, Inc.            Topic: 200

    DESCRIPTION provided by applicant The objective of this SBIR Phase I project is to develop a novel sequence specific capture SSC technology to quantitatively and robustly retrieve circulating miRNAs from blood which can transform the utility of circulating miRNAs testing in diagnosis of diseases including cancer and cardiovascular disease Circulating miRNAs have emerged as novel biomarkers ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
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