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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. A Preclinical Trial of Therapeutic Angiogenesis Plus Angioplasty and Stenting for Renal Vascular Disease

    SBC: Leflore Technologies LLC            Topic: 400

    Abstract Chronic kidney disease CKD is a progressive disorder affecting almost of the general population and this disease has shown a relentless growth over the past decades Patients with CKD have higher rates of hospitalization greater mortality shorter life expectancy and their healthcare costs are up to times more expensive than non CKD patients Thus treatments to slow halt ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Low Cost Handheld Tactile Imaging Device for Breast Cancer Screening

    SBC: VAJRA INSTRUMENTS, INC.            Topic: 102

    Palpation has been routinely used by physicians to diagnose diseases for centuries In Clinical Breast Examination CBE medical personnel screen for suspect lesions that are to fold stiffer than surrounding tissue by palpation using two or three fingers followed by precession about a fixed in contact area Typical pressure to avoid discomfort and also feel deeper palpable objects r ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. MUC assay for the early diagnosis and management of benign and malignant pancreatic diseases

    SBC: Sanguine Diagnostics And Therapeutics, Inc.            Topic: 300

    Abstract The goal of this Fast track application is to develop a non invasive diagnostic test based on MUC and MUC mucins that can serve as an adjunct to cytological analysis of fine needle aspirates FNAs for accurate prediction of malignancy in patients with cystic pancreatic lesions Due to asymptomatic nature and lack of methods for early detection andgt of pancreatic cancer PC p ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Mutation Enriched Targeted Re Sequencing

    SBC: TRANSGENOMIC, INC.            Topic: 103

    DESCRIPTION provided by applicant Low level tumor associated somatic DNA mutations can have profound implications for development of metastasis prognosis choice of treatment follow up or early cancer detection Unless they are effectively detected these low level mutations can misinform patient management decisions or become missed opportunities for personalized medicine Widely used tech ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Development of a Non adjuvanted VLP Vaccine against Stealth H N Influenza

    SBC: EPIVAX, INC.            Topic: NIAID

    DESCRIPTION provided by applicant The avian origin H N influenza virus that emerged in humans in China in presents a unique challenge to vaccine development because it is poorly immunogenic Neutralizing antibodies are not detected in acute phase infection Anti H antibody responses are significantly delayed and exhibit low avidity in comparison with antibodies generated following seas ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  6. IGF OT IGF A STAGE BASED MOBILE INTERVENTION FOR SUBSTANCE USE DISORDERS IN PRIMARY CARE N DA POP SEPTEMBER FEBRUARY BASE AWARD

    SBC: Pro-Change Behavior Systems Inc            Topic: NIDA

    Not Available

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  7. IGF OT IGF VALIDATION OF MOBILE TECHNOLOGIES FOR CLINICAL ASSESSMENT

    SBC: Pro-Change Behavior Systems Inc            Topic: NCI

    Not Available

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  8. IGF OT IGF FY IWIN NAVIGATING YOUR PATH TO WELL BEING SBIR PHASE II BASE AWARD PERIOD OF PERFORMANCE

    SBC: Pro-Change Behavior Systems Inc            Topic: NIDA

    Not Available

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Profiling Circulating miRNA Without PCR for Early Detection of Pancreatic Cancer

    SBC: VAJRA INSTRUMENTS, INC.            Topic: 102

    DESCRIPTION provided by applicant Pancreatic cancer PaC has a poor prognosis in most cases due to the lack of early detection owing to its nonspecific asymptomatic nature An effective inexpensive screening tool is needed for early diagnosis within years of tumor initiation It is well accepted that genomic instability is a hallmark of cancer Recent research indicates that less than ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Therapeutic Role of Inter-alpha Inhibitors in Wound Healing

    SBC: PROTHERA BIOLOGICS, LLC            Topic: NIAMS

    DESCRIPTION provided by applicant Wound healing is an intricately regulated process broadly characterized by phases of inflammation proliferation and remodeling Imbalances in any one of these phases can result in inadequate healing scar formation or in the development of chronic wounds such as diabetic ulcers Diabetic ulcers are responsible for the majority of lower extremity amputations ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health

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