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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. SBIR TOPIC 096: Novel Biodegradable Metal Stents for Neonatal Aortic Coarctation

    SBC: PediaStent LLC            Topic: NHLBI

    Most stents used to repair congenital heart lesions only need to serve as temporary scaffoldingsBecause pediatric patients have growing cardiovascular structuresthere is great interest in use of bioresorbable stentsBRSfor the treatment of coarctation of the aorta in neonatesA pediatric bioresorbable stent would allow thousands of infants each year to avoid the morbidity and mortality of more invas ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Localized Statin Delivery for Prevention of Primary AV Fistula Failure

    SBC: AFFINITY THERAPEUTICS, LLC            Topic: NHLBI

    Abstract Summary Arteriovenous fistulas AVFs are the preferred vascular access mode for hemodialysis patients but of AVFs fail to mature and only of mature AVFs are patent after year Vascular access failure including AVFs results from neointimal hyperplasia and contributes to andgt $ billion USD annual costs from vascular access failure including of hemodialysis patient hosp ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. HLS Durable Implantable Non Obstructive Venous Assist Device NOVAD for Support of Cavopulmonary Fontan Circulation

    SBC: Perfusion Solutions, Inc.            Topic: NHLBI

    Project Summary Abstract The proposal addresses NHLBI Topic of Special Interest HLS Development of mechanical circulatory support devices for individuals with congenital heart disease and single ventricle physiology after Fontan surgical palliation The design was specifically stimulated by the requirements outlined to Perfusion Solutions Inc PSI by pediatric and congenital surgeon Dr P ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. A Preclinical Trial of Therapeutic Angiogenesis Plus Angioplasty and Stenting for Renal Vascular Disease

    SBC: Leflore Technologies LLC            Topic: 400

    Abstract Chronic kidney disease CKD is a progressive disorder affecting almost of the general population and this disease has shown a relentless growth over the past decades Patients with CKD have higher rates of hospitalization greater mortality shorter life expectancy and their healthcare costs are up to times more expensive than non CKD patients Thus treatments to slow halt ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Testing and Commercialization of a Superior Device to Maintain Perioperative Normothermia In Anesthetized Patients

    SBC: Mercury Biomed LLC            Topic: 400

    Project Summary Abstract This proposal presents Phase of the plan of Mercury Biomed LLC for commercializing the new and innovative WarmSmart technology to more effectively keep patients warm during anesthetized surgery The WarmSmart technology is based on IP licensed from the University of Texas at Austin who is the academic partner for this STTR proposal WarmSmart embodies several breakthr ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Software for OCT Analysis of Vascular Stents

    SBC: Dyad Medical, Inc.            Topic: NHLBI

    Software for OCT Analysis of Vascular Stents PI Ronny Shalev PhD Dyad Medical Summary Dyad Medical Inc will create intravascular OCT IVOCT software for clinical live time determination of stent apposition OCTivat live the live time OCT image visualization and analysis tool and for offline analysis of stent implantation OCTivat stent Every year s of thousands of patients in the US ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. A Novel Non Cytotoxic Epigenetic Therapeutic for Sickle Cell Disease

    SBC: DeNovoTherapies LLC            Topic: NHLBI

    ABSTRACT The goal of this Fast Track proposal is to develop a novel non cytotoxic epigenetic therapeutic for life long disease modification of sickle cell disease SCD SCD is a morbid life shortening condition caused by mutated hemoglobin sickle hemoglobin HbS The pathophysiology triggered by sickle hemoglobin is interrupted by another hemoglobin that the body usually produces in utero fe ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Evolution of an Adaptable Prosthetic Foot Design for Normalization of Biomechanics During Community Participation

    SBC: OHIO WILLOW WOOD COMPANY, THE            Topic: NICHD

    Evolution of an Adaptable Prosthetic Foot Design for Normalization of Biomechanics During Community Participation Summary Abstract The vision of this project is to improve the functional physical mobility of people with lower extremity amputations so that they can more fully and confidently participate in a wider range of activities This will enhance their personal satisfaction thereby improving ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Phage accelerated test system for ID AST of urinary tract infections

    SBC: GUILD ASSOCIATES, INC.            Topic: R

    Urinary tract infections UTIs are one of the most common types of bacterial infection encountered by humans throughout their lifespan and are a major health problem afflicting millions of people each year Gram negative bacteria cause the majority of infections of which Escherichia coli is the primary pathogen and prone to antibiotic resistance The standard methods for species diagnosis and sus ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Early Feasibility Clinical Study of the VitalFlow Stimulator an Emergency Treatment for Ischemic Stroke

    SBC: NERVIVE, INC.            Topic: 105

    PROJECT SUMMARY Stroke is the world s greatest healthcare burden for which few treatment options are available The long term objective of the applicant Nervive Inc is to bring to market a non invasive medical device the VitalFlow stimulator as an emergency treatment for ischemic stroke The VitalFlow is a novel technology that activates the autonomic components of the facial nerve using pul ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health

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