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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Waterborne Transport Modeling Capability

    SBC: APPLIED SCIENCE ASSOC.            Topic: DTRA05013

    The proposed Phase II project is to provide an advanced operational waterborne transport modeling capability of chemical agents within four-dimensional marine and fresh water environments. Based upon the findings of Phase I, we propose to further enhance the operational capabilities of ASA’s Waterborne Chemical Transport Model, relative to weaponized chemical agents, by developing comprehensive ...

    SBIR Phase II 2006 Department of DefenseDefense Threat Reduction Agency
  2. Intracranial Brain Function Mapping System

    SBC: CHATTEN ASSOC., INC.            Topic: N/A

    DESCRIPTION (provided by applicant): We will develop a modern, computer-controlled electrical stimulator for performing functional mapping by cortical stimulation. The primary application is for use with patients who are candidates for surgery to control or eliminate occurrence of epileptic seizures. Other applications will include functional mapping to plan surgery for other brain diseases such a ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  3. In situ Soil Probe for Rapid Delineation of Dense Non Aqueous Phase Liquids

    SBC: DAKOTA TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): During this Phase I SBIR project, Dakota Technologies, Inc. (Dakota) will demonstrate that a simple solid state halogen specific detector can be miniaturized, hardened, and incorporated into a percussion deliverable probe capable of delineating dense non-aqueous phased liquids (DNAPL) in the subsurface in real time. The proposed system will be based on a haloge ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  4. Fluorescence Lifetime-Based Kinase Assay for HTS

    SBC: DAKOTA TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Fluorescence based-assays have greatly facilitated high-throughput screening (HTS) in drug discovery. However, in doing so, they created a bottleneck relating to false positives and false negatives, which may arise due to interferences from light scattering, inner filter effects, and compound fluorescence. Unlike fluorescence intensity, a fluorescence lifetime- ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  5. Simulation-based Dental Training System

    SBC: IDEA INTERNATIONAL, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This Phase I SBIR proposal will yield a prototype of a fully synthetic simulation-based training system to teach proper assessment, diagnosis and treatment of incipient lesions and true dental caries. IDEA International, Inc., in conjunction with the Harvard Dental School and others with experience in the simulation and virtual environment business, will create ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  6. Engineered human lgG1 for delivery of IDDM self-epitopes

    SBC: MULTICELL TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Insulin-dependent diabetes mellitus is an autoimmune disease characterized by T cell attack of pancreatic islet cells leading to irreversible loss of the insulin secreting cells. One potential strategy for combatting the autoimmune process involves the initiation of tolerigenic processes that act to tone down or turn off the ongoing cell destruction. A number ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  7. Electro-Mechanical Micro-Post Array to Detect In Vitro Muscle Contraction

    SBC: MYOMICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Myomics? technology to be developed in this Phase 1 project is based upon an in vitro skeletal muscle tissue force measurement technique for high throughput screening (HTS) of compounds to attenuate muscle weakness. The technology, termed Patterned Micro-Post-Arrays (P-fPA), is comprised of bioengineered skeletal muscle tissue attached to micro-mechanical senso ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  8. An Internet-Based Program for the Reduction and Prevention of High-Risk Drinking

    SBC: Pro-Change Behavior Systems, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The U.S. Surgeon General and the U.S. Department of Health and Human Services identified heavy drinking among college students as a major public health problem. Existing interventions generally provide alcohol education focusing on skills building, rather than tailored individualized behavior change. Harm reduction programs that do focus on behavior change have ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  9. Role of Inter-alpha Inhibitors in Anthrax Intoxication

    SBC: PROTHERA BIOLOGICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The primary goal of this proposal is to demonstrate the feasibility of utilizing Inter-alpha Inhibitor proteins (lalp) as an effective protective agent against exposure to anthrax, a lethal biological warfare agent. Inter-alpha inhibitor proteins are natural serine protease inhibitors found in relatively high concentration in human plasma. The protein complex h ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  10. Developing a Remission from Depression Questionnaire

    SBC: PSYCH PRODUCTS PRESS            Topic: N/A

    DESCRIPTION (provided by applicant): Experts in the treatment of depression have emphasized the importance of striving for remission. Studies have shown that depressed patients who respond to treatment but do not achieve remission, currently defined as a lack of symptoms, continue to experience greater likelihood of continued impairment and future recurrence of depression. However, there is much d ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
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