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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Highly efficient, compact, picosecond green laser for time resolved fluorescence
SBC: ADVR, INC. Topic: NCRRDESCRIPTION (provided by applicant): The primary goal of the Phase I effort is to establish the feasibility of fabricating waveguides to realize a significant, (10 fold), increase in performance in the output power of a picosecond pulsed green laser without increasing the peak pump power. The ultimate goal is to develop a fiber pigtailed, compact, cost-effective 530 nm picosecond laser producing 1 ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
A NEW BIOSENSOR BASED ON CATASTROPHIC PROTEIN CHANGES
SBC: ATERIS Technologies Topic: NIEHSDESCRIPTION (provided by applicant): This Phase I project will test the idea that mechanostress-sensitive, fluorescent polymers can detect structural changes induced in proteins following reaction of the protein with small molecule inhibitors. This concept will be tested and proven using recombinant acetylcholinesterase (AChE) an enzyme that is known to undergo catastrophic denaturation when it re ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
Promoting Health During Pregnancy: A Multiple Behavior Computer Tailored Interven
SBC: Pro-Change Behavior Systems, Inc. Topic: NCCDPHPDESCRIPTION (provided by applicant): Pregnant women, particularly those from underserved populations, often have a multitude of behavioral risks that threaten positive pregnancy and birth outcomes, as well as the future health of mother and baby. This application represents innovative research for impacting the promotion of healthy behaviors among pregnant women. The objective is to develop and te ...
SBIR Phase II 2010 Department of Health and Human ServicesCenters for Disease Control and Prevention -
VLP-Based Antibody-Inducing Vaccines for HIV-1
SBC: ALTRAVAX, INC Topic: NIAIDDESCRIPTION (provided by applicant): The HIV-1 epidemic has resulted in ~2.7 million new infections in 2007 for a total of ~33 million people living with HIV/AIDS. Clinical trials have shown that HIV-1 infection cannot be prevented by immunization with monomeric recombinant forms of viral envelope (Env) proteins. However, it is clear that the HIV-1 Env contains epitopes that can induce neutralizin ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
Improved Vaccines for Influenza B Virus
SBC: ALTRAVAX, INC Topic: NIAIDDESCRIPTION (provided by applicant): Influenza is a major cause of morbidity and mortality around the world. In the United States, seasonal epidemics of flu occur from late fall to early spring affecting all age groups but with especially high rates of infection in children. Serious illness and death are consequences of influenza infection among the elderly, young children, and individuals with o ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
Designing Improved HIV-1 Envelope Proteins as Vaccine Candidates
SBC: ALTRAVAX, INC Topic: NIAIDDESCRIPTION (provided by applicant): The HIV-1 epidemic has resulted in ~2.7 million new infections in 2007 for a total of ~33 million people living with HIV/AIDS. Clinical trials have shown that HIV-1 infection cannot be prevented by immunization with monomeric recombinant forms of viral envelope (Env) proteins. However, it is clear that the HIV-1 Env contains epitopes that can induce neutralizin ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
Prevention of College Student Mental Health Problems: A Web-Based ACT Program
SBC: CONTEXTUAL CHANGE, LLC Topic: NIMHDESCRIPTION (provided by applicant): There is a strong need for the development and dissemination of effective prevention programs for mental health problems with college students, who are at risk for depression, anxiety, eating disorders, substance use, and many other difficulties (American College Health Association, 2007). Despite the fact that University settings are well suited to deliver suc ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
TARGETED TWO-PHOTON PHOTODYNAMIC THERAPY TRIADS
SBC: SENSOPATH TECHNOLOGIES, INC. Topic: NCIThe objectives are to further the pre-clinical development of unique two-photon activated Photodynamic Therapy (PTD) triads that incorporate a photosensitizer, a tumor receptor targeting group, and an imaging functionality, providing a noninvasive treatment of recurrent and refractory Head and Neck (HandN) tumors deep below the skin surface, in an outpatient setting.
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
Immunotherapeutic Biomaterials for Treatment of Glioma
SBC: IN CYTU, INC. Topic: NINDSDESCRIPTION (provided by applicant): A Phase I SBIR program of preclinical development is proposed focusing on the development of an active specific immunotherapeutic called Cellarium for treatment of glial cell-based cancers. Successful completion of this project will establish the minimum level of therapeutic feasibility and lead to further development of the vaccine in preparation for f ...
SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health -
Development and Testing of Recombinant Clostridia for Cancer Therapy
SBC: SGM BIOTECH, INC. Topic: NCRRDESCRIPTION (provided by applicant): This STTR application is to develop and test for eventual clinical use a new strategy for tumor specific anticancer drug delivery. The technology, Clostridia-directed enzyme prodrug therapy, or CDEPT, exploits the fact that certain non-pathogenic bacteria of the Clostridia genus, which only grow in the absence of oxygen (hypoxia), colonize the hypoxic and necr ...
STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health