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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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he 3D Platelet Bank: A Clinical-grade, Scalable, 3D Microbioreactor Bone Marrow Mimetic for Platelet Production
SBC: KIYATEC, LLC Topic: NIBIBProject Summary Abstract The transfusion of platelets is a major component of the treatment of cancer patients undergoing chemotherapy and or bone marrow transplantstrauma patientssepsisand battlefield injuriesHoweverdue to a complete reliance upon donors as the only current approved source of plateletsand the strictshort shelf life and storage conditions of donorderived plateletscurrent supplies ...
SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health -
Polo box PLK Inhibitors Target Tumors Resistant to ATP Competitive Compounds
SBC: PPI PHARMACEUTICALS, LLC Topic: NCIPolo like kinase PLK is a central player in regulating entry into and progression through mitosis Many studies have validated PLK as an anti tumor drug target and its inhibition is potently anti proliferative to cancer cells However recent data suggests that there are two major disadvantages of the conventional approach to blocking the kinase activity of PLK First both general kinome ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Inter-alpha Inhibitors in Hypoxic-Ischemic Brain Injury
SBC: PROTHERA BIOLOGICS, INC. Topic: 105Neonatal hypoxia ischemiaHIremains a major cause of acute perinatal brain injuryleading ultimately to neurologic dysfunction manifesting as cerebral palsymental retardationand epilepsyUnfortunatelycurrent treatment and prevention strategies in newborns are limitedThere are no currently available therapies to prevent treat and or attenuate brain damage in premature infants other than supportive car ...
SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health -
A Novel Scaffold to Promote Skin Regeneration
SBC: FirstString Research, Inc Topic: NIAMSPROJECT SUMMARY Dermal scarring affects more than million people worldwide annually over million people are injured in motor vehicle accidents over million patients are severely burned and thousands of warriors are wounded in military blasts In severe burns more than of patients develop hypertrophic scar contraction which leads to hypertrophic scar contractures HSc HSc a ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Biocatalytic production of precursors to lutein and zeaxanthin to address age related macular degeneration
SBC: EscaZyme Biochemicals, LLC Topic: NProject Summary Atrophic dry age related macular degeneration AMD is the leading cause of severe loss of vision for those over age Dietary supplements containing lutein and zeaxanthin are recommended by the NEI for those at risk of late AMD There has been a corresponding growth in demand for these two xanthophylls Lutein and zeaxanthin are currently sourced from marigolds grown mostl ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Developing Testing and Validating a Wearable Alcohol Biosensor
SBC: Clinitech, LLC Topic: 450PROJECT SUMMARY This application for a Phase I SBIR award represents a collaboration between Clinitech LLC and McLean Hospital Harvard Medical School to develop a wearable biosensor for detecting alcohol in the interstitial fluid of humans who have consumed alcohol Excessive use of alcohol accounts for much of the public health burden related to alcohol use disorders including fetal ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
A Novel Millimeter wave mmw DNP EPR Front end Compatible with Versatile High field NMR Probes
SBC: DOTY SCIENTIFIC, INC. Topic: NIAA Novel Millimeter wave mmw DNP EPR Front end Compatible with Versatile High field NMR Probes Abstract There has been explosive growth in interest in Dynamic Nuclear Polarization DNP with Magic Angle Spinning MAS over the past five years because it has demonstrated S N gains exceeding two orders of magnitude at K compared to conventional MAS NMR and non spinning NMR of biological macro ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Ice Free Vitrification and nanowarming of large cartilage samples for transplantation
SBC: TISSUE TESTING TECHNOLOGIES LLC Topic: NIAMSResurfacing of articular cartilage with cold stored osteochondral allografts is employed clinically for repair of trauma and osteoarthritis induced articular cartilage surface damage Chondrocyte viability of transplanted articular cartilage is accepted as one of the determinants of outcome following osteochondral allograft transplantation We have previously developed an ice free vitrification me ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Evidence-Based Pain Intervention for Veterans: Leveraging Mobile and Social Media
SBC: Pro-Change Behavior Systems, Inc. Topic: NCCIHChronic musculoskeletal pain creates a significant public health burden, and Veterans are disproportionately affected. The frequency and extent of co-occurrence of pain and PTSD, pain and Traumatic Brain Injury (TBI), all three conditions (Post-deployment Multi-symptom Disorder (PMD), and other multi-symptom syndromes can complicate and reduce the effectiveness of pain treatment. Furthermore, the ...
SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health -
A Novel Topical HSP90 Inhibitor (CTXT-102) in the Treatment of Mild to Moderate Plaque Psoriasis
SBC: Regranion, LLC Topic: NIAMSPROJECT SUMMARY Psoriasis is a chronic inflammatory skin disease affecting approximatelymillion Americans that can become debilitating and severely impact quality of lifeWhile an estimatedof patients suffer moderate to severe disease forms that require systemic therapy with immune suppressants and ultraviolet phototherapythe majorityof patients exhibit milder symptomsFor these patientstopical agen ...
SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health