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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Reopening the Central Airway With Needle-Size Tentacle Manipulators

    SBC: Virtuoso Surgical, Inc.            Topic: NHLBI

    Project Summary AbstractThe objective of this proposal is to perform proof of concept experiments on a new hand held surgical instrument that provides dexterity at the tip of a rigid bronchoscopeThis approach is less invasive than traditional open surgeryand will be safer than the current rigid bronchoscopic approachwhich lacks dexterity in port delivered instrumentsOur new system will feature nee ...

    STTR Phase I 2018 Department of Health and Human Services
  2. Point of care assay for serodiagnosis of Leptospirosis

    SBC: Immuno Technologies, Inc.            Topic: NIAID

    Leptospirosis is the most widespread neglected zoonotic disease in the worldIt affects vulnerable populations such as rural subsistence farmers and urban slum dwellersUrban epidemics are reported in cities in developing countries and will likely increase as the world s slum population doubles tobillion byAn unexpected outbreak was reported in New York City recently and climate change may account f ...

    SBIR Phase I 2018 Department of Health and Human Services
  3. Optimizing and validating an EMG-based fetal monitor to identify true preterm labor

    SBC: PreTel, Inc.            Topic: NICHD

    External fetal monitoring is an irreplaceable clinical tool for moment to moment assessment of fetal well beingIt is performed by simultaneously measuring the fetal heart rate and uterine contractionsForyearsthe fetal heart rate has been measured using the Doppler ultrasound and uterine contractions have been assessed using the tocodynamometerTocoThe Doppler is an electronic stethoscope and the To ...

    SBIR Phase I 2018 Department of Health and Human Services
  4. Mobile-phone integrated diagnostic tests for measurements of fertility hormones

    SBC: PragmaDx, Inc.            Topic: NICHD

    PROJECT SUMMARYApproximatelyof couples trying to become pregnant will not conceive aftermonthsThe resulting infertility diagnosis and treatment regimen can be overwhelming to patientsStudies have shown that up toof enrollees will discontinue treatment before achieving a pregnancythey often cite physical and emotional burdenlogistical concerns with repeated clinic visitsand cost as reasons for endi ...

    SBIR Phase I 2018 Department of Health and Human Services
  5. Targeting DNA damage response pathways for the treatment of advanced lung cancer

    SBC: CUMBERLAND PHARMACEUTICALS INC.            Topic: 102

    ABSTRACTThere is an urgentunmet need for novel therapeutic approaches that are efficacious against lung cancerRanking first among cancer deaths in the U Sthis disease hasyear relative survival rates of andltMost lung cancers are non small cellNSCLCof casesCurative surgery is not an option for theof NSCLC patients who present with advanced stage III cancerFor these patients chemo radiation therapy ...

    SBIR Phase II 2018 Department of Health and Human Services
  6. Stage-Based Mobile Intervention for Substance Use Disorders in Primary Care: Implementation and Cluster-Randomized Trial

    SBC: Pro-Change Behavior Systems Inc            Topic: NIDA

    Nearlymillion Americans ageand olderneed treatment for a substance use disorderSUDWhile onlyof individuals requiring treatment for a SUD receive itan estimated two thirds see a primary care or urgent care provider everymonthsPrimary care providers are in a unique position to perform ScreeningBrief Interventionand Referral to TreatmentSBIRTWith Phase I contract fundingPro Change developed and pilot ...

    SBIR Phase I 2018 Department of Health and Human Services
  7. A cost-effective robotic platform for on-demand production of flexibly dosed medications in a chewable gummy dosage form

    SBC: Vitae Industries, Inc.            Topic: NICHD

    PROJECT SUMMARYThis project s goal is to develop an innovative cost effective robotic platform for fast on demand pharmacy production of pediatric drugs as individually tailored palatable gummy dosage formsMedication adherence is notoriously low among children due to difficulty swallowing pills and rejection of bad tasting medicationsAlthough some common pediatric drugs have flavored liquid formsp ...

    SBIR Phase I 2018 Department of Health and Human Services
  8. Caring for the Caregiver: A Theory-Driven Mobile Intervention to Promote Caregiver Well-Being

    SBC: Pro-Change Behavior Systems Inc            Topic: NIA

    Overmillion Americans are currently providing unpaid care to a family memberrelativeor friend with Alzheimer s disease or related dementiaWhile caregiving can be a positive experience that brings meaning and an increased sense of purposeit can also take a tollNearlyof Alzheimer s and dementia caregivers rate their emotional distress as high or very highand as many assuffer from depressionCaregiver ...

    SBIR Phase I 2018 Department of Health and Human Services
  9. MULTIFUNCTIONAL SEMI-POWERED ANKLE PROSTHESIS

    SBC: Synchro Motion LLC            Topic: NICHD

    PROJECT SUMMARY A conventional prosthetic ankle consists of a carbon fiber ankle foot complex that is nominally configured to a neutral positionThese prostheses generally work well for level walking and level ground standingbut lack the adaptability to explicitly accommodate other terrain or locomotion activitiessuch as slope walkingslope standingand stair ambulationAs suchcommon activities with a ...

    SBIR Phase I 2018 Department of Health and Human Services
  10. Rapid Test to Assist Therapy in Neonatal Sepsis and Necrotizing Enterocolitis

    SBC: PROTHERA BIOLOGICS, LLC            Topic: R

    The primary goal of this proposed research is to develop a rapid point of care test that assesses the risk of neonatal sepsisNSand or necrotizing enterocolitisNECin infants based on Inter alpha inhibitor proteinsIAIPlevels in bloodThe test is expected to be simpleuser friendlyportable and suitable for use in the NICUNS and NEC are associated with high mortality and morbidityincluding adverse neuro ...

    SBIR Phase I 2018 Department of Health and Human Services

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