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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Trainable Early Warning System for Epileptic Seizures

    SBC: CHATTEN ASSOC., INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Individuals with epilepsy, their families and the professionals that treat them have long felt the need for reliable warning of an impending epileptic seizure. In Phase I, we developed a unique, multi-parameter, individualized, trainable seizure predetection system which extracts spectral, wavelet and time domain features and uses recurrent neural networks to ...

    SBIR Phase II 2005 Department of Health and Human Services
  2. OptiFit Wheelchair Fitting System

    SBC: BENEFICIAL DESIGNS INC            Topic: N/A

    DESCRIPTION (provided by applicant): There, is a high incidence of overuse injuries among manual wheelchair users. One method to prevent the development or delay the onset of injuries is to reduce the physical demand on the user during wheelchair propulsion. Configuration of the wheelchair can have a significant effect on the effort required to propel the wheelchair; however, the optimal setup re ...

    SBIR Phase I 2005 Department of Health and Human Services
  3. Universal Design Guidelines for Fitness Equipment

    SBC: BENEFICIAL DESIGNS INC            Topic: N/A

    DESCRIPTION (provided by applicant): People with disabilities have increased health risks as a result of a sedentary lifestyle. Limited access to fitness equipment is a primary barrier to physical activity and a significant environmental barrier to the health and well-being of people with disabilities. This project will develop design, construction and installation guidelines for the universal de ...

    SBIR Phase I 2005 Department of Health and Human Services
  4. Implanted Membranes for Characterization and Monitoring

    SBC: DAKOTA TECHNOLOGIES, INC.            Topic: N/A

    This NIH SBIR Phase II project will enable Dakota Technologies, Inc. (DTI) to complete development of a hollow-fiber membrane (HFM) sampling system that provides analytical quality data on volatile organic compounds (VOCs) in groundwater. The system is versatile and comprehensive; it incorporates methods and hardware for implanting the HFM samplers, methods and hardware for efficiently collecting ...

    SBIR Phase II 2005 Department of Health and Human Services
  5. A Genome-Derived, Epitope-Driven H. Pylori Vaccine

    SBC: EPIVAX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): EpiVax discovers and develops epitqpe-driven vaccines by screening microbial genomes for protective epitopes. In this application, we describe a genome-based approach for the development of a therapeutic vaccine against Helicobacter pylori disease. First, the H. pylori genome will be scanned for immunodominant Th epitopes by computer-driven (EpiMatrix) analysi ...

    SBIR Phase I 2005 Department of Health and Human Services
  6. Novel Smallpox Vaccine Derived from VV/VAR Immunome

    SBC: EPIVAX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): EpiVax specializes in the development of epitope-driven vaccines by screening whole genomes for candidate vaccine components. In this application, we propose to develop a safe, new smallpox vaccine based on epitopes conserved between the vaccinia virus (VV) and Variola (VAR) 'immunomes' that could be used as both a prophylactic and a therapeutic intervention in ...

    SBIR Phase I 2005 Department of Health and Human Services
  7. Recombinant IalphaIp: Treatment for Sepsis

    SBC: MULTICELL TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Sepsis is the systematic and overwhelming response to infection. Once triggered, an uncontrolled cascade of coagulation, impaired fibrinolysis, and inflammation drive disease progression. This results in damage to the lungs, liver, kidney and cardiovascular system, leading to multiple organ failure and an associated high mortality rate in severe sepsis disease ...

    SBIR Phase I 2005 Department of Health and Human Services
  8. Multi-media Obesity Prevention Program for Adolescents

    SBC: Pro-Change Behavior Systems Inc            Topic: N/A

    DESCRIPTION (provided by applicant): Obesity is recognized as a major public health concern and has become a national health priority. With the prevalence of adolescent obesity nearly triple what it was two decades ago, effective interventions to prevent and treat overweight and obesity among adolescents are needed. Programs to enhance the healthy behaviors related to obesity prevention with cost- ...

    SBIR Phase II 2005 Department of Health and Human Services
  9. Multiple Behavior Change Internet Program for Colleges

    SBC: Pro-Change Behavior Systems Inc            Topic: N/A

    DESCRIPTION (provided by applicant): Unhealthy eating, lack of exercise, and poor stress management habits are started in adolescence and have been shown to initiate or promote chronic diseases. Well-designed health promotion programs are needed to assist college students in shaping a foundation of healthy behaviors. This Phase I application proposes the development of a multiple behavior change p ...

    SBIR Phase I 2005 Department of Health and Human Services
  10. A Stage-Based Expert System for Teen Dating Violence Prevention

    SBC: Pro-Change Behavior Systems Inc            Topic: N/A

    DESCRIPTION (provided by applicant): Male-to-female intimate partner violence accounts for 26% of violence-related injuries in women presenting in hospital emergency departments and 30% of all female homicides. Early to mid-adolescence provides an excellen t window of opportunity for the prevention of intimate partner violence. Patterns of relating in intimate relationships are still relatively ...

    SBIR Phase I 2005 Department of Health and Human Services

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