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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Inter-alpha Inhibitors in Hypoxic-Ischemic Brain Injury
SBC: PROTHERA BIOLOGICS, INC. Topic: 105Neonatal hypoxia ischemiaHIremains a major cause of acute perinatal brain injuryleading ultimately to neurologic dysfunction manifesting as cerebral palsymental retardationand epilepsyUnfortunatelycurrent treatment and prevention strategies in newborns are limitedThere are no currently available therapies to prevent treat and or attenuate brain damage in premature infants other than supportive car ...
SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health -
Biocatalytic production of precursors to lutein and zeaxanthin to address age related macular degeneration
SBC: EscaZyme Biochemicals, LLC Topic: NProject Summary Atrophic dry age related macular degeneration AMD is the leading cause of severe loss of vision for those over age Dietary supplements containing lutein and zeaxanthin are recommended by the NEI for those at risk of late AMD There has been a corresponding growth in demand for these two xanthophylls Lutein and zeaxanthin are currently sourced from marigolds grown mostl ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Developing Testing and Validating a Wearable Alcohol Biosensor
SBC: Clinitech, LLC Topic: 450PROJECT SUMMARY This application for a Phase I SBIR award represents a collaboration between Clinitech LLC and McLean Hospital Harvard Medical School to develop a wearable biosensor for detecting alcohol in the interstitial fluid of humans who have consumed alcohol Excessive use of alcohol accounts for much of the public health burden related to alcohol use disorders including fetal ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Evidence-Based Pain Intervention for Veterans: Leveraging Mobile and Social Media
SBC: Pro-Change Behavior Systems, Inc. Topic: NCCIHChronic musculoskeletal pain creates a significant public health burden, and Veterans are disproportionately affected. The frequency and extent of co-occurrence of pain and PTSD, pain and Traumatic Brain Injury (TBI), all three conditions (Post-deployment Multi-symptom Disorder (PMD), and other multi-symptom syndromes can complicate and reduce the effectiveness of pain treatment. Furthermore, the ...
SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health -
Novel Antigen-Specific Immunomodulatory Tregitope-based Therapy to Address Autoimmune Pathogenesis in Graves' Disease
SBC: EPIVAX, INC. Topic: 200ABSTRACT SignificanceGravesdiseaseGDone of the most prevalent autoimmune diseasesis caused by stimulating autoantibodiesTSAbto the Thyroid Stimulating Hormone ReceptorTSHRresulting in hyperthyroidismCurrent methods for managing hyperthyroidism in GD target excess thyroid hormone secretion by ablation or removal of the thyroid or by blocking thyroid hormone synthesisEach of these therapies is assoc ...
SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Trainable Early Warning System for Epileptic Seizures
SBC: CHATTEN ASSOC., INC. Topic: N/ADESCRIPTION (provided by applicant): Individuals with epilepsy, their families and the professionals that treat them have long felt the need for reliable warning of an impending epileptic seizure. In Phase I, we developed a unique, multi-parameter, individualized, trainable seizure predetection system which extracts spectral, wavelet and time domain features and uses recurrent neural networks to ...
SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health -
OptiFit Wheelchair Fitting System
SBC: BENEFICIAL DESIGNS INC Topic: N/ADESCRIPTION (provided by applicant): There, is a high incidence of overuse injuries among manual wheelchair users. One method to prevent the development or delay the onset of injuries is to reduce the physical demand on the user during wheelchair propulsion. Configuration of the wheelchair can have a significant effect on the effort required to propel the wheelchair; however, the optimal setup re ...
SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health -
Universal Design Guidelines for Fitness Equipment
SBC: BENEFICIAL DESIGNS INC Topic: N/ADESCRIPTION (provided by applicant): People with disabilities have increased health risks as a result of a sedentary lifestyle. Limited access to fitness equipment is a primary barrier to physical activity and a significant environmental barrier to the health and well-being of people with disabilities. This project will develop design, construction and installation guidelines for the universal de ...
SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health -
Implanted Membranes for Characterization and Monitoring
SBC: DAKOTA TECHNOLOGIES, INC. Topic: N/AThis NIH SBIR Phase II project will enable Dakota Technologies, Inc. (DTI) to complete development of a hollow-fiber membrane (HFM) sampling system that provides analytical quality data on volatile organic compounds (VOCs) in groundwater. The system is versatile and comprehensive; it incorporates methods and hardware for implanting the HFM samplers, methods and hardware for efficiently collecting ...
SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health -
A Genome-Derived, Epitope-Driven H. Pylori Vaccine
SBC: EPIVAX, INC. Topic: N/ADESCRIPTION (provided by applicant): EpiVax discovers and develops epitqpe-driven vaccines by screening microbial genomes for protective epitopes. In this application, we describe a genome-based approach for the development of a therapeutic vaccine against Helicobacter pylori disease. First, the H. pylori genome will be scanned for immunodominant Th epitopes by computer-driven (EpiMatrix) analysi ...
SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health