Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Reduced gluten cereal grains

    SBC: Arcadia Biosciences, Inc.            Topic: 300

    DESCRIPTION provided by applicant Celiac disease CD is the most common food sensitive enteropathy known affecting approximately of the population and its incidence appears to be on the rise In addition non celiac gluten sensitivity GS has recently been revealed to be a distinct condition that affects a growing number of individuals Both of these conditions are triggered by gluten a ...

    STTR Phase II 2015 Department of Health and Human Services
  2. Optimization of an integrin enhancing molecule for the treatment of Duchenne muscular dystrophy

    SBC: STRYKAGEN CORPORATION            Topic: NIAMS

    DESCRIPTION provided by applicant Duchenne muscular dystrophy is caused by mutations in the dystrophin gene resulting in the loss of the dystrophin glycoprotein complex in skeletal muscle Loss of dystrophin results in reduced sarcolemmal integrity progressive muscle damage and compromised muscle function There is currently no cure and limited treatment options for DMD and all affected child ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  3. Synactix Pharmaceuticals I-Corps Application

    SBC: SYNACTIX PHARMACEUTICALS, INC.            Topic: 102

    DESCRIPTION provided by applicant Polypharmacology represents a new and attractive approach to treat malignances as lasting and robust efficacy could be obtained through the inhibition of multiple survival pathways with one therapeutic agent In line with this method we have designed a RET rearranged during transfection VEGFR vascular endothelial growth factor receptor small molecule ...

    STTR Phase I 2015 Department of Health and Human Services
  4. Pre-IND study of PMT-254, a pan-FLT3 inhibitor for the treatment of FLT3 driven cancers.

    SBC: PROMUTECH PHARMACEUTICALS, INC.            Topic: 102

    DESCRIPTION provided by applicant Pathological activating mutations in the FLT kinase represent the most common genetic alteration in patients with acute myeloid leukemia AML occurring in approximately one third of cases Recently we performed translational studies that identified drug resistant kinase domain mutations in FLT ITD at the time of relapse in AML patients treated with the FLT ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Extraction and Characterization of a Safer, Cost-effective Anti-inflammatory

    SBC: Botanisol LLC            Topic: R

    DESCRIPTION provided by applicant Inflammatory disease states are leading causes of death and disability and a major cost to healthcare in the United States There is an epidemic of death and hospitalizations due to adverse effects from NSAIDs TAI LCx Turmeric Anti Inflammatory Lipophilic Component X is a novel anti inflammatory discovered in previously unrecognized pharmacologically activ ...

    STTR Phase I 2015 Department of Health and Human Services
  6. Prediction and Measurement of the Carbon Build-Up in Film-Cooled Rocket Engines

    SBC: SIERRA ENGINEERING, INC.            Topic: AF15AT21

    ABSTRACT: Sierra Engineering Inc. (Sierra) believes that existing chemical kinetic models can be efficiently incorporated into commercial CFD codes to predict the mixing, pyrolysis, soot formation and carbon deposition within film cooled rocket engines. During this Phase I STTR effort we will demonstrate that this analysis capability is practical and that we can generate appropriate model validati ...

    STTR Phase I 2015 Department of DefenseAir Force
  7. The Replacement of Chromium Electroplate for High Wear/High Temperature Applications

    SBC: Physics, Materials, and Applied Mathematics Research L.L.C.            Topic: AF15AT31

    ABSTRACT: This proposal translates a non-toxic, aqueous-based, near room temperature electrodeposition process to completely eliminate Cr (VI) for the production of wear and corrosion resistant surfaces on high-strength steel. Specifically, our process will produce adherent and crack-free Re-based coatings that are extremely high-temperature (Tm of Re = 3180oC), lubricious, wear-resistant, and cor ...

    STTR Phase I 2015 Department of DefenseAir Force
  8. Snapshot Imaging Laser Displacement Sensor for Hypervelocity Diagnostic Testing

    SBC: CONTROL VISION INC            Topic: AF15AT38

    ABSTRACT: The Air Force is interested in hypersonic (M>5) systems that enable time-critical missions for strike and Intelligence, Surveillance, Reconnaissance (ISR). Perhaps more so than for any other flight regime, precise and accurate sensing of key phenomena is difficult without contaminating the data being collected. Control Vision, Inc has developed unique optical profilometry technology whic ...

    STTR Phase I 2015 Department of DefenseAir Force
  9. Robust Mid-IR Optical Fibers

    SBC: AdValue Photonics Inc            Topic: AF15AT02

    ABSTRACT: The development of mid-infrared (Mid-IR) transparent fibers having low propagation loss in the wavelength range 2-5 micron, robust mechanical properties, low temperature sensitivity and high laser power delivery capability has been investigated extensively in the last decade. Chalcogenide glass fibers, fluoride glass fibers, tellurite glass fibers, and microstructured silica fibers have ...

    STTR Phase I 2015 Department of DefenseAir Force
  10. Development of an Efficient Flutter and Limit Cycle Oscillation Predictive Tool

    SBC: Zona Technology, Inc            Topic: AF14AT04

    ABSTRACT: Several current fighter aircraft with external store configurations persistently encounter Limit Cycle Oscillation (LCO) problems. A fast and accurate aeroelastic prediction is required to identify the critical LCO configurations given the massive number of aircraft with store combinations short-time frame demanded by rapid military responses when facing todays ever-changing internation ...

    STTR Phase I 2015 Department of DefenseAir Force
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