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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Extreme Wear-Resistant Materials

    SBC: C K Technologies LLC            Topic: AF09BT19

    Successful completion of the proposed Phase I work outlined and follow-on Phase II work will provide a system to rank existing materials and coatings for severe wear applications. In addition, the ranking system can be utilized to identify desirable properties in new materials and/or coatings that could be developed for specific severe wear applications. The validated system resulting from the Ph ...

    STTR Phase I 2010 Department of DefenseAir Force
  2. Innovative Combat Simulation to Craft Tomorrow’s UAV Operational Doctrine

    SBC: DECISIVE POINT LLC            Topic: AF09BT31

    Could the future military use of UAV create a revolution in military affairs as great as the introduction of the airplane or the tank? Is the revolution underway now? If so, how can we best prepare our military for success? The advent of Unmanned Aerial Vehicles (UAV) is once more changing present and future aerial warfare. The configuration, deployment, and face of the United States Air Force ...

    STTR Phase I 2010 Department of DefenseAir Force
  3. Reactive Fusion Welding for Ultra-High Temperature Ceramic Composite Joining

    SBC: MO-SCI Corp.            Topic: AF09BT24

    For this Phase I program, MO-SCI Corporation and Missouri University of Science and Technology (Missouri S&T) will develop reactive fusion and reactive plasma welding techniques that are capable of joining ultra-high temperature ceramic (UHTC) composites. Past work at Missouri S&T demonstrated the feasibility of fusion welded UHTC composites. This program will build on the joining successes at M ...

    STTR Phase I 2010 Department of DefenseAir Force
  4. Implementation of Facility Models Using Neural Networks for Improved Control of Wind Tunnels

    SBC: INNOVATIVE TECH APPLICATIONS LLC            Topic: AF09BT16

    Test facilities such as wind tunnels require stringent control of test parameters such as wind speed, temperature, pressure, etc., in order to satisfy the objectives of the simulation. Control of test facilities can be significantly improved using mathematical models for the facility behavior that are developed from physical principles. A shortcoming of mathematical control models is that they t ...

    STTR Phase I 2010 Department of DefenseAir Force
  5. Hierarchically-Structured Bio-Electrocatalyst Materials Design

    SBC: Akermin Incorporated            Topic: AF09BT03

    Akermin proposes, in collaboration with the University of New Mexico, to demonstrate the viability of electronic connections between biomolecules and engineered surfaces in order to harvest power and energy through biologic systems. This work is in part based on Akermin’s proprietary enzyme stabilization technology, which can be used for many lower power commercial and military applications, in ...

    STTR Phase I 2010 Department of DefenseAir Force
  6. Detection of mtDNA Mutations at Zeptomole Sensitivity without PCR

    SBC: GENEPROTECH,INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Mitochondrial disease caused by point mutations in mitochondrial DNA (mtDNA) can be a formidable diagnostic challenge. Because clinical presentation is variable, multisystemic, and mimics many other neurological disorders, ruling out a mtDNA etiology is difficult in patients with suspected myopathies or encephalopathies. Screening for mtDNA mutations that caus ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  7. Role of Inter-alpha Inhibitors in Anthrax Intoxication

    SBC: PROTHERA BIOLOGICS, LLC            Topic: NIAID

    DESCRIPTION (provided by applicant): Anthrax is recognized as a class A bio-threat microbial pathogen that is readily weaponized and exceedingly difficult to treat. This bacterium is highly virulent inducing lethal infection in immunologically normal hosts by its intrinsic capacity to disseminate rapidly and induce sepsis, along with its ability to generate two highly potent exotoxins, lethal toxi ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  8. Tiptuximab Immunotherapeutic for Cancer

    SBC: Medical Guidance Systems LLC            Topic: NCI

    ? DESCRIPTION (provided by applicant): Poor prognosis cancers such as lung cancer, glioblastoma, pancreatic cancer and others have 3 year survival rates that range from 1%-15%. Recent advancements in the development of therapeutic antibodies haveshown promise in other cancers such as breast, head and neck, and colon cancer. The limitations in antibody development are the paucity of cancer ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Galectin 1: A novel small protein therapy for Duchenne muscular dystrophy

    SBC: STRYKAGEN CORPORATION            Topic: NIAMS

    DESCRIPTION provided by applicant Duchenne Muscular Dystrophy DMD is a fatal muscle disease affecting in every male births DMD results from mutations in the gene encoding the dystrophin a kDa scaffolding protein responsible for providing a mechanical link between the muscle fiber actin cytoskeleton and a transmembrane protein complex called the dystrophin associated glycoprotein ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Identification of Borrelia burgdorferi diagnostic biomarkers in humans and nonhum

    SBC: DxDiscovery Incorporated            Topic: NIAID

    DESCRIPTION provided by applicant The number of Lyme disease cases in the US has been recently estimated by the CDC at cases year This is major public health concern Currently available diagnostics rely on detection of the antibody response serology to Borrelia burgdorferi the causative agent of Lyme disease However serological tests are not accurate during the early stages of Ly ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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