Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. INTELLIGENT MOUTHGUARD FOR MEASURING HEAD IMPACTS IN YOUTH ATHLETES

    SBC: Sportsguard Laboratories, Inc.            Topic: NICHD

    DESCRIPTION provided by applicant With million young athletes participating in contact sports and between to million concussions endured by young athletes yearly in the US subjective concussion identification increases risk of death time lost from school cognitive decline chronic traumatic encephalopathy CTE depression suicide dementia Alzheimerandapos s and Parkinsona ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  2. IRE1 alpha inhibitors for type 2 diabetes

    SBC: Optikira, LLC            Topic: 200

    DESCRIPTION provided by applicant The American Diabetes Association has declared type diabetes T D a public health crisis T D begins as a state of compensated insulin resistance frank disease develops when of insulin producing pancreatic islet cells of affected individuals undergo cell death Endoplasmic reticulum ER stress has emerged as a central underlying mechanism that drive ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  3. IRE1 alpha inhibitors for Retinal Degenerative Diseases

    SBC: Optikira, LLC            Topic: N

    DESCRIPTION provided by applicant Approximately Americans suffer from vision loss due to Retinitis Pigmentosa RP Despite significant progress in elucidating the molecular genetics of RP over the past three decades no disease modifying therapies have been approved There is compelling evidence implicating endoplasmic reticulum ER stress in the pathogenesis of various forms of RP e ...

    STTR Phase I 2015 Department of Health and Human Services
  4. Optimization of an integrin enhancing molecule for the treatment of Duchenne muscular dystrophy

    SBC: STRYKAGEN CORPORATION            Topic: NIAMS

    DESCRIPTION provided by applicant Duchenne muscular dystrophy is caused by mutations in the dystrophin gene resulting in the loss of the dystrophin glycoprotein complex in skeletal muscle Loss of dystrophin results in reduced sarcolemmal integrity progressive muscle damage and compromised muscle function There is currently no cure and limited treatment options for DMD and all affected child ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Interface for the collection, analysis, and visualization of simulation performance data

    SBC: Perduco Group, Inc., The            Topic: AF15AT14

    ABSTRACT: To complement capabilities of future autonomous systems, the Air Force requires interoperable tools & methodologies to design, verify, validate, assess & operate human-machine system interactions associated with autonomous and manned systems integration. Often the human performance measures and status of each simulation is reported independently making it challenging to analyze the data. ...

    STTR Phase I 2015 Department of DefenseAir Force
  6. MHZ-RATE NONLINEAR SPECTROSCOPY AND IMAGING PLATFORM FOR TRANSIENT AND NONEQUILIBRIUM FLOWS

    SBC: Spectral Energies, LLC            Topic: AF15AT20

    ABSTRACT: The objective of the proposed research effort is to demonstrate the feasibility of 100 kHz to 1 MHz nonlinear spectroscopy for measurements of molecular energy distributions, energy transfer, major species, and temperature in transient combusting and nonequilibrium flows. This will be accomplished, in part, by extending burst-mode laser technology to the fs and ps regimes for greater tha ...

    STTR Phase I 2015 Department of DefenseAir Force
  7. Prediction and Measurement of the Carbon Build-Up in Film-Cooled Rocket Engines

    SBC: SIERRA ENGINEERING, INC.            Topic: AF15AT21

    ABSTRACT: Sierra Engineering Inc. (Sierra) believes that existing chemical kinetic models can be efficiently incorporated into commercial CFD codes to predict the mixing, pyrolysis, soot formation and carbon deposition within film cooled rocket engines. During this Phase I STTR effort we will demonstrate that this analysis capability is practical and that we can generate appropriate model validati ...

    STTR Phase I 2015 Department of DefenseAir Force
  8. Environmentally-compliant composite coating for corrosion and wear protection of structural metals

    SBC: ECOSIL TECHNOLOGIES LLC            Topic: AF15AT31

    ABSTRACT: The goal of this proposal is to demonstrate the feasibility of a novel environmentally-compliant process to produce an advanced alloy coating(s) that imparts excellent corrosion and wear resistance to structural metals on military aircraft and weapon systems. The resulting composite coating and the coating process do not consist of any hazardous materials such as heavy metals chromium (C ...

    STTR Phase I 2015 Department of DefenseAir Force
  9. In Situ Quantitative Spatially-resolved Ablation Diagnostics in High-Enthalpy Flows

    SBC: Spectral Energies, LLC            Topic: AF15AT38

    ABSTRACT: The objective of the STTR Phase-I effort proposed by Spectral Energies LLC and The University of Tennessee is to demonstrate the feasibility of an in situ quantitative measurement of the products generated by the degradation of a material surface exposed to a hypersonic environment. The concept is based on a state-of-the-art diagnostic method: Coherent Microwave Rayleigh Scattering from ...

    STTR Phase I 2015 Department of DefenseAir Force
  10. Terahertz Frequency Materials Testing at Cryogenic Temperatures and in High Magnetic Fields

    SBC: Lake Shore Cryotronics, Inc.            Topic: AF12BT08

    ABSTRACT: Temperature and magnetic field dependent terahertz spectroscopies have proven useful for characterizing novel electronic and magnetic materials. To this end, we are developing a turn-key, continuous-wave (CW) terahertz transmission platform operating from 5 K to 300 K with fields up to 9 T. Fiber-coupled photoconductive switches operate from 200 GHz to 1.2 THz in the cryogenic and high-f ...

    STTR Phase II 2015 Department of DefenseAir Force
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