Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Real-time myoglobin saturation measurement to assess benefit of RBC transfusion

    SBC: Opticyte, Inc.            Topic: NHLBI

    DESCRIPTION provided by applicant Critically ill patients commonly arrive at an intensive care unit with anemia While blood transfusions are the standard of care with the intention to increase or maintain oxygen delivery to tissues questions have been raised about the benefit of blood transfusions particularly in non bleeding patients with moderate anemia A noninvasive measure of intracellu ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  2. A DOPPLER SIMULATOR FOR VASCULAR ULTRASOUND TRAINING

    SBC: Sheehan Medical LLC            Topic: NIBIB

    DESCRIPTION provided by applicant Doppler ultrasound is relied upon as the primary and often the only test used to diagnose vascular pathology Because variations in technical skill directly impact surgical referral decisions there is a strong clinical need to ensure that provides both attain and maintain skills in this procedure The problem we address is the lack of a quantitative or standar ...

    STTR Phase II 2015 Department of Health and Human Services
  3. Continuous measurement of cell growth as an optimal tool in drug toxicity testing (Supplement)

    SBC: EnTox Sciences LLC            Topic: NCATS

    DESCRIPTION provided by applicant During the process of screening for drugs with therapeutic potential often times several candidates emerge as prime candidates with similar efficacy and the choice for a lead compound is difficult to make However peopleandapos s lives and billions of dollars may rest on the choice of which compound to bring to clinical investigation and trials Since any lev ...

    STTR Phase I 2015 Department of Health and Human Services
  4. Optimization of an integrin enhancing molecule for the treatment of Duchenne muscular dystrophy

    SBC: STRYKAGEN CORPORATION            Topic: NIAMS

    DESCRIPTION provided by applicant Duchenne muscular dystrophy is caused by mutations in the dystrophin gene resulting in the loss of the dystrophin glycoprotein complex in skeletal muscle Loss of dystrophin results in reduced sarcolemmal integrity progressive muscle damage and compromised muscle function There is currently no cure and limited treatment options for DMD and all affected child ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Ultra-Sensitive Diagnosis of AIDS-Related Tuberculosis

    SBC: AttoDx, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant This grant will develop a novel strategy to enhance the analytical sensitivity of polymerase chain reaction PCR based detection of bacteria in samples We will commercialize the strategy in the form of a pre PCR andquot turbo chargerandquot to be marketed in conjunction with PCR based molecular diagnostic systems The current STTR project will apply this str ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  6. Clonotyping Technology for Prediction of Antibiotic Resistance

    SBC: ID Genomics SPC            Topic: NIAID

    DESCRIPTION provided by applicant The primary goal of this Phase I STTR proposal is to develop a prototype of a rapid molecular diagnostics test to improve prediction of the antibiotic resistance of uropathogenic Escherichia coli by determining their clonal identity clonotype The clonotype determination will be done by detection of the presence absence of a limited number d of single ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  7. Optimized Additive Manufacturing for High Dielectric Strength

    SBC: TETHERS UNLIMITED, INC.            Topic: AF15AT07

    ABSTRACT: To produce high dielectric strength insulator materials, our approach, called Optimized Additive Manufacturing for High Dielectric Strength (OAHDS), will optimize fused filament fabrication (FFF) 3D printing in order to fabricate high density parts. Currently, thermoplastics 3D printed via FFF have dielectric strengths one to three orders of magnitude lower than injection molded parts ma ...

    STTR Phase I 2015 Department of DefenseAir Force
  8. Prediction and Measurement of the Carbon Build-Up in Film-Cooled Rocket Engines

    SBC: SIERRA ENGINEERING, INC.            Topic: AF15AT21

    ABSTRACT: Sierra Engineering Inc. (Sierra) believes that existing chemical kinetic models can be efficiently incorporated into commercial CFD codes to predict the mixing, pyrolysis, soot formation and carbon deposition within film cooled rocket engines. During this Phase I STTR effort we will demonstrate that this analysis capability is practical and that we can generate appropriate model validati ...

    STTR Phase I 2015 Department of DefenseAir Force
  9. Printed Skin (pSkin) for Aircraft Sensing and Testing

    SBC: Quest Integrated, LLC            Topic: AF14AT01

    ABSTRACT: With the increasing demand on structural performance as well as decreasing size and weight of advanced flying structures, there is a reduction in the available volume for aircraft instrumentation. In addition, integral fabrication of structures using composite materials and close integration and optimization of aircraft system and subsystems limit further access and space for sensors, ...

    STTR Phase I 2015 Department of DefenseAir Force
  10. A Doppler Simulator for Vascular Ultrasound Training

    SBC: Sheehan Medical LLC            Topic: NIBIB

    We will develop and test a simulator of diagnostic vascular ultrasound for use in medical education and professional certification. The simulator will include not only two-dimensional (2D) images but also Doppler spectral waveforms to simulate duplex ultrasound scanning. The rationale is that education in diagnostic ultrasound has traditionally been based on an extended duration of clinical exposu ...

    STTR Phase I 2014 Department of Health and Human Services
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