Award Data

DESCRIPTION provided by applicant Neglected Tropical Diseases NTD which include helminthiasis and leishmaniasis are a group of thirteen parasitic and bacterial infections that affect over billion people Although these are devastating diseases of global concern their neglected status relative to other health concerns has resulted in a limited arsenal of therapeutic compounds for their ...

DESCRIPTION provided by applicant Substance use disorders SUDs continue to be one of the most serious public health problems in the US Studies have consistently documented a substantially higher prevalence of SUDs among individuals under criminal justice supervision At year end approximately million adults were under criminal justice supervision in the US of which million i ...

DESCRIPTION provided by applicant Substance use disorders SUDs continue to be one of the most serious public health problems in the US Studies have consistently documented a substantially higher prevalence of SUDs among individuals under criminal justice supervision At year end approximately million adults were on probation or parole in adults African American probationer ...

DESCRIPTION provided by applicant Glucocorticoids GCandapos s such as prednisolone are used frequently to induce remission and treat rheumatoid arthritis RA Despite effectiveness many GC mediated detrimental side effects including osteoporosis and muscle atrophy limit long term chronic treatment of RA patients In addition juvenile arthritis patients suffer from th side effect of signi ...

DESCRIPTION provided by applicant Falls are a leading cause of injuries and deaths among older adults OAs and will be an increasing public health concern given projections of future increases in the number of OAs in the US Fall detection and or surveillance systems are needed to enhance an OAandapos s confidence and independence and to facilitate rapid post fall responses This project wil ...

DESCRIPTION provided by applicant Duchenne Muscular Dystrophy DMD is a fatal muscle disease affecting in every male births DMD results from mutations in the gene encoding the dystrophin a kDa scaffolding protein responsible for providing a mechanical link between the muscle fiber actin cytoskeleton and a transmembrane protein complex called the dystrophin associated glycoprotein ...

DESCRIPTION provided by applicant The number of Lyme disease cases in the US has been recently estimated by the CDC at cases year This is major public health concern Currently available diagnostics rely on detection of the antibody response serology to Borrelia burgdorferi the causative agent of Lyme disease However serological tests are not accurate during the early stages of Ly ...

ABSTRACT: To maintain superiority in the battle domains of space, ground, air and sea, it is natural that the U.S. move toward incorporating autonomous capabilities to enhance/replace the traditional role of humans. Continued advances in processing capability and techniques to employ decision logic and adaptive learning strategies will soon make this vision reality. To deploy any such capability o ...

DESCRIPTION provided by applicant Approximately of the population experiences elevated depressive symptoms Kubik et al Despite recent research suggesting that overall population mortality would be reduced by if the effects of subthreshold depression could be blocked completely the majority of individuals with elevated depressive symptoms never receive evidence based treat ...

ABSTRACT: Our main objective in this project is to propose a novel Structured Sparse Priors for Target Recognition (SSPTR) system and to demonstrate that discriminative applications such as data clustering or target detection, tracking, and classification can be solved effectively and directly on the compressed measurement domain without the need to recover the original data. Our proposed sparse-r ...