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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Nonlinear Computation Tool to Chart Trajectories of Bipolar Disorder

    SBC: Biomedical Development Corporation            Topic: 103

    DESCRIPTION provided by applicant Bipolar disorder BD is a complex chronic illness characterized by recurrent often dramatic mood changes Self management of BD is an important component of treatment but is likewise complex and can be fraught with difficulties including misunderstanding of the condition and a lack of self awareness Combined with the nationwide shortage of mental healthcare ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Galectin 1: A novel small protein therapy for Duchenne muscular dystrophy

    SBC: STRYKAGEN CORPORATION            Topic: NIAMS

    DESCRIPTION provided by applicant Duchenne Muscular Dystrophy DMD is a fatal muscle disease affecting in every male births DMD results from mutations in the gene encoding the dystrophin a kDa scaffolding protein responsible for providing a mechanical link between the muscle fiber actin cytoskeleton and a transmembrane protein complex called the dystrophin associated glycoprotein ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Identification of Borrelia burgdorferi diagnostic biomarkers in humans and nonhum

    SBC: DXDISCOVERY INC            Topic: NIAID

    DESCRIPTION provided by applicant The number of Lyme disease cases in the US has been recently estimated by the CDC at cases year This is major public health concern Currently available diagnostics rely on detection of the antibody response serology to Borrelia burgdorferi the causative agent of Lyme disease However serological tests are not accurate during the early stages of Ly ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Design, Reconfigure, and Evaluate Autonomous Models in Training

    SBC: TIER 1 PERFORMANCE SOLUTIONS LLC            Topic: AF15AT14

    ABSTRACT: The proliferation of autonomous- and human-machine systems necessitates the creation of new tools for system design and evaluation. Key among these are simulation testbeds that support interactions between multiple warfighters and systems, and methods for creating and integrating intelligent agent models into simulation environments. We see a significant opportunity to advance the state ...

    STTR Phase I 2015 Department of DefenseAir Force
  5. Reverberation Mitigation of Speech

    SBC: MINERVA SYSTEMS & TECHNOLOGIES LLC            Topic: AF15AT17

    ABSTRACT: Speech recognition technology is in wide use today and has been successfully integrated in a number of applications. Most of these applications require a microphone located near the talker. However, when a distant microphone is used where the speaker is at some distance from the microphone as in a hands-free communication, or in a meeting room, there is a major problem with the captured ...

    STTR Phase I 2015 Department of DefenseAir Force
  6. Prediction and Measurement of the Carbon Build-Up in Film-Cooled Rocket Engines

    SBC: SIERRA ENGINEERING, INC.            Topic: AF15AT21

    ABSTRACT: Sierra Engineering Inc. (Sierra) believes that existing chemical kinetic models can be efficiently incorporated into commercial CFD codes to predict the mixing, pyrolysis, soot formation and carbon deposition within film cooled rocket engines. During this Phase I STTR effort we will demonstrate that this analysis capability is practical and that we can generate appropriate model validati ...

    STTR Phase I 2015 Department of DefenseAir Force
  7. Improving the therapeutic efficacy of a lead vaccine against plague using a novel adjuvant system

    SBC: FasCure Therapeutics LLC            Topic: NIAID

    DESCRIPTION provided by applicant FasCure Therapeutics focuses on the development of adjuvant systems to generate prophylactic and therapeutic immune responses The major objective of this Phase STTR proposal is to reformulate a lead plague subunit vaccine with a novel adjuvant system to improve its protective efficacy Yersinia pestis is the causative agent of bubonic and pneumonic plague ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  8. Optimization of an integrin enhancing molecule for the treatment of Duchenne muscular dystrophy

    SBC: STRYKAGEN CORPORATION            Topic: NIAMS

    DESCRIPTION provided by applicant Duchenne muscular dystrophy is caused by mutations in the dystrophin gene resulting in the loss of the dystrophin glycoprotein complex in skeletal muscle Loss of dystrophin results in reduced sarcolemmal integrity progressive muscle damage and compromised muscle function There is currently no cure and limited treatment options for DMD and all affected child ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Decision Making under Uncertainty for Dynamic Spectrum Access

    SBC: INFOBEYOND TECHNOLOGY LLC            Topic: AF13AT02

    ABSTRACT: Due to scarcity of spectrum, Dynamic Spectrum Access (DSA) becomes a needed technology to improve the utilization of electromagnetic spectrum for DoD satellite communication. However, current DSA approaches are developed for terrestrial communications without addressing the unique challenges for SATCOM environments such as error-prone spectrum sensing, high mobility, and large coverage. ...

    STTR Phase I 2014 Department of DefenseAir Force
  10. Secure Efficient Cross-domain Protocols

    SBC: INFOBEYOND TECHNOLOGY LLC            Topic: AF13AT08

    ABSTRACT: Coordinating and sharing information across multi-level security (MLS) networks are of great interest in many military applications. However, it is very challenging to accomplish those goals due to the heterogeneous security classifications of different network domains. The recent proposed cross-domain solutions (CDS) provide initial steps to make such applications possible. However, th ...

    STTR Phase I 2014 Department of DefenseAir Force
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