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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Prediction and Measurement of the Carbon Build-Up in Film-Cooled Rocket Engines
SBC: SIERRA ENGINEERING, INC. Topic: AF15AT21ABSTRACT: Sierra Engineering Inc. (Sierra) believes that existing chemical kinetic models can be efficiently incorporated into commercial CFD codes to predict the mixing, pyrolysis, soot formation and carbon deposition within film cooled rocket engines. During this Phase I STTR effort we will demonstrate that this analysis capability is practical and that we can generate appropriate model validati ...
STTR Phase I 2015 Department of DefenseAir Force -
New Assays for Expression Profiling of MicroRNAs
SBC: Nawgen, LLC Topic: 172DESCRIPTION provided by applicant MicroRNAs miRNAs are involved in many diverse biological processes and a single miRNA can modulate the expression of hundreds of gene targets Changes in miRNA expression could have profound biological impacts leading to a variety of human diseases To date most miRNA expression profiling studies have relied on microarrays or high throughput RNA sequencing ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Rational design of small interfering RNA for genome-wide target knockdown
SBC: Nawgen, LLC Topic: 172DESCRIPTION provided by applicant RNA interference RNAi is a small RNA guided gene silencing process within living cells The RNAi technique is widely used in both biological research and clinical applications because it has the ability to knockdown essentially any gene of interest However one major unresolved issue in RNAi studies is non specific gene silencing It is well known that in ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Optimization of an integrin enhancing molecule for the treatment of Duchenne muscular dystrophy
SBC: STRYKAGEN CORPORATION Topic: NIAMSDESCRIPTION provided by applicant Duchenne muscular dystrophy is caused by mutations in the dystrophin gene resulting in the loss of the dystrophin glycoprotein complex in skeletal muscle Loss of dystrophin results in reduced sarcolemmal integrity progressive muscle damage and compromised muscle function There is currently no cure and limited treatment options for DMD and all affected child ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Tiptuximab Immunotherapeutic for Cancer
SBC: Medical Guidance Systems LLC Topic: NCI? DESCRIPTION (provided by applicant): Poor prognosis cancers such as lung cancer, glioblastoma, pancreatic cancer and others have 3 year survival rates that range from 1%-15%. Recent advancements in the development of therapeutic antibodies haveshown promise in other cancers such as breast, head and neck, and colon cancer. The limitations in antibody development are the paucity of cancer ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Galectin 1: A novel small protein therapy for Duchenne muscular dystrophy
SBC: STRYKAGEN CORPORATION Topic: NIAMSDESCRIPTION provided by applicant Duchenne Muscular Dystrophy DMD is a fatal muscle disease affecting in every male births DMD results from mutations in the gene encoding the dystrophin a kDa scaffolding protein responsible for providing a mechanical link between the muscle fiber actin cytoskeleton and a transmembrane protein complex called the dystrophin associated glycoprotein ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Identification of Borrelia burgdorferi diagnostic biomarkers in humans and nonhum
SBC: DXDISCOVERY INC Topic: NIAIDDESCRIPTION provided by applicant The number of Lyme disease cases in the US has been recently estimated by the CDC at cases year This is major public health concern Currently available diagnostics rely on detection of the antibody response serology to Borrelia burgdorferi the causative agent of Lyme disease However serological tests are not accurate during the early stages of Ly ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Extreme Wear-Resistant Materials
SBC: C K TECHNOLOGIES LLC Topic: AF09BT19Successful completion of the proposed Phase I work outlined and follow-on Phase II work will provide a system to rank existing materials and coatings for severe wear applications. In addition, the ranking system can be utilized to identify desirable properties in new materials and/or coatings that could be developed for specific severe wear applications. The validated system resulting from the Ph ...
STTR Phase I 2010 Department of DefenseAir Force -
Innovative Combat Simulation to Craft Tomorrow’s UAV Operational Doctrine
SBC: DECISIVE POINT LLC Topic: AF09BT31Could the future military use of UAV create a revolution in military affairs as great as the introduction of the airplane or the tank? Is the revolution underway now? If so, how can we best prepare our military for success? The advent of Unmanned Aerial Vehicles (UAV) is once more changing present and future aerial warfare. The configuration, deployment, and face of the United States Air Force ...
STTR Phase I 2010 Department of DefenseAir Force -
Reactive Fusion Welding for Ultra-High Temperature Ceramic Composite Joining
SBC: MO-SCI Corp. Topic: AF09BT24For this Phase I program, MO-SCI Corporation and Missouri University of Science and Technology (Missouri S&T) will develop reactive fusion and reactive plasma welding techniques that are capable of joining ultra-high temperature ceramic (UHTC) composites. Past work at Missouri S&T demonstrated the feasibility of fusion welded UHTC composites. This program will build on the joining successes at M ...
STTR Phase I 2010 Department of DefenseAir Force