Award Data

ABSTRACT: Sierra Engineering Inc. (Sierra) believes that existing chemical kinetic models can be efficiently incorporated into commercial CFD codes to predict the mixing, pyrolysis, soot formation and carbon deposition within film cooled rocket engines. During this Phase I STTR effort we will demonstrate that this analysis capability is practical and that we can generate appropriate model validati ...

ABSTRACT: Rice in concert with Inview Technologies will design, simulate, and evaluate compressive algorithms for object detection and classification in both static and dynamic imaging. The eventual goal is the application of the most suitable methods in novel short-wave and mid-wave infrared optical architectures for high-speed discovery and tracking by exploiting sparse signatures. We will compa ...

ABSTRACT: In order to meet future needs for cost-effective high-capacity, secure telemetry systems, communication systems, smart weapons systems, UAVs, satellites, and other DoD platforms, further advances and innovations in digital-to-analog conversion must be achieved to support the migration to higher frequencies and operation in shared spectrum environments. This dictates a requirement for tr ...

ABSTRACT: The principal thrust of the proposed research is the development and testing of a high-speed (MHz range) sensor for measuring the shear stress beneath a hypersonic boundary layer at elevated temperatures. The development of such a sensor will enable the Air-Force to develop more robust empirical models for predicting the wall shear stress in complex 3-D flows. The proposed sensor inno ...

DESCRIPTION provided by applicant A number of pharmaceutical reactions and wash processes involve interaction between immiscible phases within reactors or extraction equipment Multi phase synthesis processes have been traditionally been carried out through dispersion of one of the phases into the other in the form of droplets Such arrangement increases the surface area of interaction thereby ...

DESCRIPTION provided by applicant Breast cancers in African American AA women are characterized by earlier onset higher aggressiveness more extensive metastases and increased mortality rates compared to those in European American EA women This breast cancer related health disparity is partly due to the fact that AA women are more likely than EA women to develop a particularly aggressive ...

DESCRIPTION provided by applicant Adolescent and young adult AYA hematopoietic stem cell transplantation HSCT patients face a variety of well documented physical and emotional challenges In addition to undergoing a life threatening procedure that involves an intense treatment regimen and lengthy hospital stay these patients face a protracted month recovery period marked by numerous phy ...

DESCRIPTION provided by applicant This proposal is for a phase I II fast track project for the STTR program with the main goal to develop a blood test for Alzheimerandapos s disease AD diagnosis AD is the most common dementia in the elderly population and one of the leading causes of death in the developed world One of the main problems in AD is the lack of an early sensitive and objective ...

DESCRIPTION provided by applicant Three medications are approved by the FDA as treatments for alcohol dependence disulfiram acamprosate and naltrexone but these are seldom prescribed due to poor efficacy or side effects Another topiramate is effective for reducing alcohol use but it causes a range of side effects that limit its tolerability Another clas of potentially effective treatment ...

DESCRIPTION provided by applicant Duchenne muscular dystrophy is caused by mutations in the dystrophin gene resulting in the loss of the dystrophin glycoprotein complex in skeletal muscle Loss of dystrophin results in reduced sarcolemmal integrity progressive muscle damage and compromised muscle function There is currently no cure and limited treatment options for DMD and all affected child ...