Award Data

This proposal addresses the development and use of lightweight, low thermal-capacity reformable tooling materials for high-temperature composite processing evaluation, parts prototyping, trial production and full-rate production of PMC engine components. The weight-saving promise of high-temperature polymer matrix composites (PMCs) for engine components is offset by the very high costs of parts m ...

New missions require that airborne radars operate at increasing ranges with higher target resolution. This combination necessitates the cost-effective deployment of large apertures while maintaining aerodynamic performance. Externally mounted antenna arrays are not a satisfactory solution due to the large size at low frequencies, for example with UHF foliage penetration radar. Another approach emp ...

DESCRIPTION (provided by applicant): We will develop a modern, computer-controlled electrical stimulator for performing functional mapping by cortical stimulation. The primary application is for use with patients who are candidates for surgery to control or eliminate occurrence of epileptic seizures. Other applications will include functional mapping to plan surgery for other brain diseases such a ...

DESCRIPTION (provided by applicant): During this Phase I SBIR project, Dakota Technologies, Inc. (Dakota) will demonstrate that a simple solid state halogen specific detector can be miniaturized, hardened, and incorporated into a percussion deliverable probe capable of delineating dense non-aqueous phased liquids (DNAPL) in the subsurface in real time. The proposed system will be based on a haloge ...

DESCRIPTION (provided by applicant): Fluorescence based-assays have greatly facilitated high-throughput screening (HTS) in drug discovery. However, in doing so, they created a bottleneck relating to false positives and false negatives, which may arise due to interferences from light scattering, inner filter effects, and compound fluorescence. Unlike fluorescence intensity, a fluorescence lifetime- ...

DESCRIPTION (provided by applicant): This Phase I SBIR proposal will yield a prototype of a fully synthetic simulation-based training system to teach proper assessment, diagnosis and treatment of incipient lesions and true dental caries. IDEA International, Inc., in conjunction with the Harvard Dental School and others with experience in the simulation and virtual environment business, will create ...

DESCRIPTION (provided by applicant): Insulin-dependent diabetes mellitus is an autoimmune disease characterized by T cell attack of pancreatic islet cells leading to irreversible loss of the insulin secreting cells. One potential strategy for combatting the autoimmune process involves the initiation of tolerigenic processes that act to tone down or turn off the ongoing cell destruction. A number ...

DESCRIPTION (provided by applicant): Myomics? technology to be developed in this Phase 1 project is based upon an in vitro skeletal muscle tissue force measurement technique for high throughput screening (HTS) of compounds to attenuate muscle weakness. The technology, termed Patterned Micro-Post-Arrays (P-fPA), is comprised of bioengineered skeletal muscle tissue attached to micro-mechanical senso ...

This Phase II SBIR Program will investigate and demonstrate the feasibility of extending OptiComp’s (OCC) intelligent distributed data communications architecture and optoelectronic (OE) interconnect technology to inter-satellite data communication systems. OCC’s proprietary optoelectronic interconnect technology provides multiband optical communication by integrating multi-wavelength VCSEL an ...

DESCRIPTION (provided by applicant): The U.S. Surgeon General and the U.S. Department of Health and Human Services identified heavy drinking among college students as a major public health problem. Existing interventions generally provide alcohol education focusing on skills building, rather than tailored individualized behavior change. Harm reduction programs that do focus on behavior change have ...