Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Osteopontin targeted therapy for primary CNS lymphoma

    SBC: MODULATION THERAPEUTICS, INC.            Topic: 102

    Abstract Primary central nervous system lymphoma PCNSL is an aggressive brain tumor with a dire unmet therapeutic need It has an overall incidence of per person years and is regarded as an orphan disease with potential for fast track approval Our group made a discovery via gene expression analysis that osteopontin OPN is the most upregulated gene in PCNSL compared to its non CNS ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Developing Multi-targeting Antiviral Agents Against Herpes Simplex 1

    SBC: Quercus Molecular Design, LLC            Topic: NIAID

    Viruses from the human herpesvirus family are estimated to infectof the adult population worldwide and are responsible for lifelong debilitating and congenital infectionsSome members of this family are associated with human cancers and age related cognitive declineHerpes simplex virusHSVhas infected more thanbillion people under the age ofof the populationHSVcauses significant disease during acute ...

    STTR Phase I 2017 Department of Health and Human Services
  3. Biocatalytic production of precursors to lutein and zeaxanthin to address age related macular degeneration

    SBC: EscaZyme Biochemicals, LLC            Topic: N

    Project Summary Atrophic dry age related macular degeneration AMD is the leading cause of severe loss of vision for those over age Dietary supplements containing lutein and zeaxanthin are recommended by the NEI for those at risk of late AMD There has been a corresponding growth in demand for these two xanthophylls Lutein and zeaxanthin are currently sourced from marigolds grown mostl ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Instant k-Space Tomography for Spatial-Spectral Monitoring

    SBC: Phase Sensitive Innovations, Inc.            Topic: AF17AT013

    The Army is frequently forced to operate in hostile climates. Heavy fog, rain, snow, and dust storms can inhibit the performance of tracking technologies such as mid-wave infrared cameras. In such conditions, Army early warning systems are blinded and put personnel and assets at risk. There is a specific need for a degraded visual environment (DVE) penetrative target tracking solution. Radio fre ...

    STTR Phase I 2017 Department of DefenseAir Force
  5. Compact Passive Millimeter Wave Sensor for GPS-denied Navigation

    SBC: Phase Sensitive Innovations, Inc.            Topic: AF15AT26

    Under the proposed effort, PSI will leverage a novel pmmW imaging technology developed under a prior Navy program to realize the low size, weight, and power sensors required for UAV implementation.This technology is based on an optical upconverted distributed aperture technology that can make large effective apertures in low SWaP form factors thereby maximizing achievable resolution.This sensor te ...

    STTR Phase II 2017 Department of DefenseAir Force
  6. Wafer-Level Electronic-Photonic Co-Packaging

    SBC: Phase Sensitive Innovations, Inc.            Topic: AF16AT01

    In this STTR effort we will develop key packaging techniques for wafer-level hybrid electrical-optical co-packaging based on silicon photonic platform. These techniques include packaging LiNbO3 modulator on insulator (LNOI), high-speed modified uni-traveling carrier (MUTC) photodiodes packaging and high-efficiency fiber coupling. Silicon is the desired host material for photonic integrated circuit ...

    STTR Phase I 2017 Department of DefenseAir Force
  7. Prediction and Measurement of the Soot Build-Up in Film-Cooled Rocket Engines

    SBC: JOHNSON ROCKETS            Topic: AF15AT21

    This Phase II STTR effort is focused on generating the data necessary to identify the phenomenology that produces carbon deposition within kerosene film cooled rocket engines.This data is essential to guide the model development and validation process.Program outputs will be both data and a physics-based model for carbon deposition.

    STTR Phase II 2017 Department of DefenseAir Force
  8. Bayesian Inference of Spacecraft Geometry and Pose

    SBC: VISION SYSTEMS INC.            Topic: AF17AT007

    Space platforms are complex dynamical systems and there are many reasons to model them from ground telescope imagery as well as from space-based sensor platforms. One key motivation is to determine the operational state and configuration of the vehicle. Key questions such as did the solar panels fail to deploy, did the object begin to tumble unexpectedly may be addressed by a sufficiently detaile ...

    STTR Phase I 2017 Department of DefenseAir Force
  9. Efficient Arrays for Generating Light Emission (EAGLE)

    SBC: Chip Design Systems LLC            Topic: AF16AT22

    With today's IRLED devices, >99.4% of input electrical power is converted into parasitic/waste heat. Moreover, as the local temperatures of the pixels increase due to the generated heat, IRLED optical efficiency is further reduced. Overall this severely limits the number and intensity of array pixels that can be simultaneously operated at high apparent temperatures. In Phase 2, we focus on develop ...

    STTR Phase II 2017 Department of DefenseAir Force
  10. Robust Predictor of Breast Cancer Risk

    SBC: Morgan and Mendel Genomics, Inc.            Topic: 103

    Summary Approximatelymillion women in the United States are at high risk for developing breast cancerbased on inheritance of a germline mutation in a gene in the double strand breakDSBrepair and cyclin checkpoint pathwaysMany are unaware of their genetic predispositionsbecause their family history is uninformative or unknownGenetic testing is important for identifying mutations in these genesbut i ...

    STTR Phase I 2017 Department of Health and Human Services
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