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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Biocatalytic production of precursors to lutein and zeaxanthin to address age related macular degeneration

    SBC: EscaZyme Biochemicals, LLC            Topic: N

    Project Summary Atrophic dry age related macular degeneration AMD is the leading cause of severe loss of vision for those over age Dietary supplements containing lutein and zeaxanthin are recommended by the NEI for those at risk of late AMD There has been a corresponding growth in demand for these two xanthophylls Lutein and zeaxanthin are currently sourced from marigolds grown mostl ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Neuro Optical Diagnostic System for Macular Degeneration

    SBC: NEUROFIELDZ INC.            Topic: NIA

    Age related macular degeneration AMD causes progressive loss of central vision and is the leading cause of blindness in the developed world A major challenge in the development of effective treatments for AMD is the lack of sensitive practical visual function endpoints People with AMD manifest delayed dark adaptation DA recovery and DA tests are a FDA approved method for diagnosing AMD Cu ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Therapeutic game based exercise during hemodialysis to improve balance and mobility

    SBC: BIOSENSICS LLC            Topic: NIA

    Abstract Chronic kidney disease CKD disproportionately impacts older adults Balance mobility and falls are serious problems for CKD patients due to associated peripheral neuropathy and peripheral arterial disease which also contribute to foot ulcers and other foot problems in this population Among older adults these problems are often compounded by other comorbid conditions leaving older ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. My MESSAGE Improving Wayfinding and Reducing Challenging Behaviors in Persons with Dementia Through the Use of RFID Technology

    SBC: HEARTHSTONE ALZHEIMER CARE LTD.            Topic: NIA

    In the proposed study we will develop and evaluate a product called My MESSAGE Multimedia Ecopsychosocial Support System for Alzheimer s within Geriatric Environments which will circumvent the limitations of traditional visual cues and also provide unprecedented flexibility and precision for assisting with wayfinding and reducing other challenging behaviors in PWD The target consumer for MM w ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Drug eluting Brachytherapy Implants for Chemo radiation Therapy

    SBC: TheraNano LLC            Topic: 102

    Prostate cancer PCa is the second leading cause of cancer death in American men with deaths and new cases estimated in the US in Radiation therapy is one of the standard therapies for high and intermediate risk patients and is a non surgical therapy option for low risk patients A combined chemo radiation therapy CRT approach has been shown in several trials to improve s ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Development of Structure Based Potential for Protein Mapping

    SBC: ACPHARIS            Topic: 100

    The binding sites of proteins include smaller regions called hot spots that are major contributors to the binding free energy and hence are crucial to binding any ligand at that site Hot spots can be determined by screening libraries of fragment sized organic molecules for binding to the target protein by X ray crystallography or nuclear magnetic resonance NMR The computational mapping algori ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. MISSION U A Multimedia Training Tool for Treating Individuals with Co occurring Mental Health and Substance Use Disorders

    SBC: PRAXIS, INC.            Topic: 350

    Millions of U S adults suffer from a co occurring mental health and substance use disorder COD A COD is often difficult for providers to address and thus clients may experience poor treatment engagement symptom exacerbations homelessness incarceration and often utilize acute and emergency services increasing medical expenditures Currently the healthcare delivery system needs but does ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Development of Alkontrol herbal for Treating Alcohol Abuse

    SBC: NATURAL PHARMACIA INTERNATIONAL, INC.            Topic: 350

    This application for a Fast Track STTR award represents a collaboration between Natural Pharmacia InternationalIncNPIand McLean Hospital to initiate steps toward commercializing a isoflavone botanical product for treating alcoholismExcessive use of alcohol accounts for much of the public health burden related to alcohol use disordersincluding fetal alcohol syndromefatal motor crashesaccidents and ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Universal Multivariate Information Measures for Multisensor Inference (UMIMMI)

    SBC: BOSTON FUSION CORP            Topic: AF16AT29

    The team of Boston Fusion Corp., University of Illinois at Urbana-Champaign, and Syracuse University proposes Phase II of UMIMMI: Universal Multivariate Information Measures for Multisensor Inference, a research program that studies multivariate information measures and uses these to construct optimal, universal algorithms and to lay a framework for general multivariate reasoning. We can then appl ...

    STTR Phase II 2017 Department of DefenseAir Force
  10. Numerical Tools for Predicting Drug Dissolution Profiles

    SBC: RES Group, Inc.            Topic: NIGMS

    Project SummaryNumerical Tools for Predicting Drug Dissolution Profiles This STTR Phase II proposal describes the development of a modeling framework that combines a mesoscopic model for hydrodynamics with disintegration and dissolution kinetic models in order to accurately describe the dissolution behavior of tabletsThe complexities of the tablet dissolution problem have led to the development of ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
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