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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Dietary Supplement As Adjunct Therapy In Castration-Resistant Prostate Cancer

    SBC: MetCure Therapeutics LLC            Topic: 102

    DESCRIPTION provided by applicant Castration Resistant Prostate Cancer Castration resistant prostate cancer CRPC directly contributes to patient mortality It is imperative to develop new and effective adjunct therapy to enhance the response of CRPC to hormonal therapy Recently we developed ProFineTM a proprietary formula consisting of bioactive flavonoids enriched in pomegranate fruit and ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Alternative Methods for Creating a Sodium Guidestar

    SBC: TPhotonics Inc.            Topic: AF17AT005

    The purpose of this proposed research is to develop and commercialize a novel two color sodium guidestar laser operating simultaneously at 589 nm and 1141 nm. Our patented T-cavity design combined with VECSEL technology will be the basis for the guidestar development. The polychromatic laser guidestar (PLGS) system being proposed currently does not exist and would allow for the correction of atmos ...

    STTR Phase I 2017 Department of DefenseAir Force
  3. Alternative Methods for Creating a Sodium Guidestar

    SBC: HART SCIENTIFIC CONSULTING INTERNATIONAL L.L.C.            Topic: AF17AT005

    The objective of the proposed research is to demonstrate high-power, scalable, and stable laser sources at specific wavelengths with narrow linewidth matched to the single velocity class of mesospheric atomic sodium for guide star application. The operation at tailored wavelengths, 1141 nm and 1178 nm (for 589 nm via frequency doubling) is addressed by the use of bandgap-engineered optically pumpe ...

    STTR Phase I 2017 Department of DefenseAir Force
  4. A MODULAR, EXPANDABLE, LOW COST MBE SYSTEM FOR A NEW GENERATION OF EPITAXY

    SBC: Innovative Advanced Materials, Inc.            Topic: AF16AT25

    Innovative Advanced Materials (IAM), Inc., founded by MBE expert Dr. W. Alan Doolittle, has developed a new generation of MBE tools with revolutionary capability and remarkably lower cost than legacy tools and proposes to construct a prototype tool to demonstrate its power. The prototype tool will be delivered to AFRL for use in the growth of Gallium Oxide shattering current technical roadblocks c ...

    STTR Phase II 2017 Department of DefenseAir Force
  5. Anti CCL mAb to treat castration resistant prostate cancer

    SBC: JYANT Technologies, Inc.            Topic: 102

    Metastatic castration resistant prostate cancer CRPC PCa accounts for of PCa deaths and is associated with skeletal metastases CRPC affects patients differently making this disease difficult for physicians to provide standardized treatments with similar outcomes Docetaxel can prolong the overall survival in patients with metastatic CRPC but current therapies do not provide a cure Doce ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Anti-CXCL13 mAb to mitigate prostate cancer health disparities

    SBC: JYANT Technologies, Inc.            Topic: NIMHD

    DESCRIPTION provided by applicant The most common metastatic site for hormone refractory prostate cancer HRPC PCa is bone While docetaxel can prolong the overall survival in patients with metastatic HRPC current treatments do not provide a cure Further complicating the matter HRPC is a disease that affects a variety of patients differently which can be problematic for physicians to prov ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  7. Application of PPODA QT for embolization of aneurysms

    SBC: ANEUVAS TECHNOLOGIES INC            Topic: 101

    A cerebral aneurysm is an abnormal enlargement or pouch that forms from a weakened vessel segment in the brain Often going unnoticed and untreated an aneurysm can cause a sudden and catastrophic hemorrhage or stroke Approximately of patients die from an aneurysm rupture even before receiving medical attention and of patients die despite medical treatment Patients that survive typical ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Bayesian Inference of Spacecraft Geometry and Pose

    SBC: VISION SYSTEMS INC            Topic: AF17AT007

    Space platforms are complex dynamical systems and there are many reasons to model them from ground telescope imagery as well as from space-based sensor platforms. One key motivation is to determine the operational state and configuration of the vehicle. Key questions such as did the solar panels fail to deploy, did the object begin to tumble unexpectedly may be addressed by a sufficiently detaile ...

    STTR Phase I 2017 Department of DefenseAir Force
  9. Biocatalytic production of precursors to lutein and zeaxanthin to address age related macular degeneration

    SBC: EscaZyme Biochemicals, LLC            Topic: N

    Project Summary Atrophic dry age related macular degeneration AMD is the leading cause of severe loss of vision for those over age Dietary supplements containing lutein and zeaxanthin are recommended by the NEI for those at risk of late AMD There has been a corresponding growth in demand for these two xanthophylls Lutein and zeaxanthin are currently sourced from marigolds grown mostl ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Biomimetic Wound Healing Devices to Close Diabetic Wounds

    SBC: PROTEIN GENOMICS INC.            Topic: NIDDK

    The long term objective of this project is the synthesis and assembly of wound healing devices that mimic as closely as possible the biochemical and mechanical characteristics of healthy human skin The proposed research would focus on the synthesis of membranes containing electrospun human recombinant tropoelastin and collagen mixtures The ratios of the two molecules and the spinning condition ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
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