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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Soluble E NTPDase for sepsis

    SBC: Purine Pharmaceuticals Inc.            Topic: NIGMS

    SUMMARY Sepsis is a medical condition caused by an overwhelming systemic inflammatory response to infection Although the underlying infection can now be efficiently treated with antibiotics there are no effective therapies to control the organ damage caused by the inflammatory response of the host As a result sepsis is the leading cause of mortality in intensive care units and is the tenth lea ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. A practical and versatile high resolution D dosimetry system for clinical use

    SBC: HEURIS INC.            Topic: 102

    Quality assurance QA is a critical component of radiation oncology that ensures both effective treatment delivery and patient safety Over the last decade dQA is now particularly important asramatic innovations in treatment delivery technologiesy have led to increasingly sophisticated and complex treatments that are difficult to adequately verify with conventional dosimetric verification system ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Telehealth Intervention for Improved Blood Pressure Control with Targeted Incentives Using New Technologies and Insights From Behavioral Economics to Increase the Effectiveness of Behavioral Change

    SBC: Wellth Inc.            Topic: NIA

    PROJECT SUMMARY ABSTRACT Hypertension or sustained systolic and diastolic blood pressure BP of and mm Hg or higher is among the most frequently encountered conditions in primary care in the U S The estimated prevalence is among all U S adults and increases with age to affect of seniors Hypertension is also the leading risk factor for cardiovascular disease global mortality ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Biocatalytic production of precursors to lutein and zeaxanthin to address age related macular degeneration

    SBC: EscaZyme Biochemicals, LLC            Topic: N

    Project Summary Atrophic dry age related macular degeneration AMD is the leading cause of severe loss of vision for those over age Dietary supplements containing lutein and zeaxanthin are recommended by the NEI for those at risk of late AMD There has been a corresponding growth in demand for these two xanthophylls Lutein and zeaxanthin are currently sourced from marigolds grown mostl ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Small Molecule Therapy for the Treatment of Heart Failure

    SBC: SUMOCOR LLC            Topic: NHLBI

    ABSTRACT The incidence of heart failure HF continues to increase in the United States despite significant advances in pharmacological therapies and novel devices There is an acute need for novel treatment strategies for heart failure A key abnormality in HF is defective handling of calcium that has been partially related to abnormal sarcoplasmic reticulum SR function in cardiac myocytes Red ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Spectrum Localization for Improved Situational Awareness

    SBC: MAXENTRIC TECHNOLOGIES, LLC            Topic: AF17AT013

    There is a demand for scalable, wideband architectures that support spectrum monitoring, source localization, and emitter classification. RF spectrum is becoming increasingly congested as the number of emitters grows and their bandwidths widen. Technologies that improve the DoDs ability to create an accurate, detailed assessment of operating spectrum are critical to improving situational awarenes ...

    STTR Phase I 2017 Department of DefenseAir Force
  7. Lithium Ion / Super Capacitor Hybrid System

    SBC: Electro Standards Laboratory, Inc.            Topic: A15AT010

    A scalable hybrid lithium ion battery / super capacitor energy storage device is developed and the technology is matured such that the system reduces battery cell stress, improves temperature range, and increases effective battery lifetime and safety. This is an enabling technology that allows the use of very high energy batteries in applications that would otherwise be unsuitable for them.

    STTR Phase II 2017 Department of DefenseArmy
  8. Prediction and Measurement of the Soot Build-Up in Film-Cooled Rocket Engines

    SBC: JOHNSON ROCKETS            Topic: AF15AT21

    This Phase II STTR effort is focused on generating the data necessary to identify the phenomenology that produces carbon deposition within kerosene film cooled rocket engines.This data is essential to guide the model development and validation process.Program outputs will be both data and a physics-based model for carbon deposition.

    STTR Phase II 2017 Department of DefenseAir Force
  9. Bayesian Inference of Spacecraft Geometry and Pose

    SBC: VISION SYSTEMS INC.            Topic: AF17AT007

    Space platforms are complex dynamical systems and there are many reasons to model them from ground telescope imagery as well as from space-based sensor platforms. One key motivation is to determine the operational state and configuration of the vehicle. Key questions such as did the solar panels fail to deploy, did the object begin to tumble unexpectedly may be addressed by a sufficiently detaile ...

    STTR Phase I 2017 Department of DefenseAir Force
  10. Stacked 2-D Meta-structures for Shielding High-Power Laser Radiation

    SBC: UTILITY DEVELOPMENT CORP            Topic: A17AT003

    The objective will be to investigate novel approaches using multilayered hybrid 2-dimensional nanostructures as passive coatings and evaluate their interactions with high energy lasers. This approach will be applied throughout the entire EM spectra. Simulations will be the main focus and will augment these with preliminary experiments in the visible range. These structured materials will be ...

    STTR Phase I 2017 Department of DefenseArmy

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