Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. A Cloud based Application for the Joint Analysis of Multiple Big Data Types

    SBC: MathNimbus Inc            Topic: 400

    Project Summary Technology advances now enable the cost effective acquisition of Kandgt distinct data types from a common set of N bio samples where i the kth data type is represented by a data matrix with columns containing Pk measurements in N samples for k K and ii at least one of the data types is big i e Pk is much bigger than N for some k The rapid accumulation of such mult ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. A novel racial disparity marker for risk prediction in triple negative breast cancer patients

    SBC: NOVAZOI THERANOSTICS            Topic: NIMHD

    DESCRIPTION provided by applicant Breast cancers in African American AA women are characterized by earlier onset higher aggressiveness more extensive metastases and increased mortality rates compared to those in European American EA women This breast cancer related health disparity is partly due to the fact that AA women are more likely than EA women to develop a particularly aggressive ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  3. Aminooxyacetic Acid Prodrugs for Colon Cancer Therapy

    SBC: CBS THERAPEUTICS, INC.            Topic: 102

    ABSTRACT Recent studies of the applicants support the role of the endogenous gaseous biological mediator hydrogen sulfide H S in colorectal cancer In specific the selective upregulation of cystathionine synthase CBS and the subsequent production of H S in colonic cancer cells serves as a pro survival factor by stimulating tumor cell bioenergetics ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. An eHealth solution for posttraumatic stress and pain screening integrated in pediatric injury care

    SBC: Radiant Creative Group, LLC            Topic: NICHD

    ABSTRACT Pediatric injury is the leading cause of child mortality and acquired disability in the United Statesaffectingmillion children annuallyAmong school age children alonemore thanmillion are treated in Emergency Department or admitted to the hospital annually for injuryincurring billions in medical and work loss costs each yearAfter hospital dischargemany injured children experience pain that ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Aspirin-PC for Chemoprevention of Colorectal Cancer

    SBC: PLx Opco Inc.            Topic: NCI

    ABSTRACT Colorectal cancerCRCis the third leading cause of cancer related deaths in the U SBased on numerous epidemiological studies and recent prospective clinical trialsthe use of daily aspirin is associated with a significant reduction in CRC incidencedeaths and metastatic spreadHoweverthe chronic use of this drug is limited due to the side effects of gastrointestinal bleeding ulceration in sus ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Bayesian Inference of Spacecraft Geometry and Pose

    SBC: VISION SYSTEMS INC.            Topic: AF17AT007

    Space platforms are complex dynamical systems and there are many reasons to model them from ground telescope imagery as well as from space-based sensor platforms. One key motivation is to determine the operational state and configuration of the vehicle. Key questions such as did the solar panels fail to deploy, did the object begin to tumble unexpectedly may be addressed by a sufficiently detaile ...

    STTR Phase I 2017 Department of DefenseAir Force
  7. Biocatalytic production of precursors to lutein and zeaxanthin to address age related macular degeneration

    SBC: EscaZyme Biochemicals, LLC            Topic: N

    Project Summary Atrophic dry age related macular degeneration AMD is the leading cause of severe loss of vision for those over age Dietary supplements containing lutein and zeaxanthin are recommended by the NEI for those at risk of late AMD There has been a corresponding growth in demand for these two xanthophylls Lutein and zeaxanthin are currently sourced from marigolds grown mostl ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Biomechanical Rat Testing Device to Validate Primary Blast Loading Conditions for Mild Traumatic Brain Injury

    SBC: BAKER ENGINEERING AND RISK CONSULTANTS, INC.            Topic: A17AT022

    BakerRisk proposes to use their extensive experience with shock testing, pressure transducers, and accelerometers, along with expertise in animal testing and the study of traumatic brain injury provided by their collaborator, Dr. David Cook, to produce a biomechanical surrogate of a rat. This device will stand in for the animal specimen in a variety of laboratory and in the field tests, recording ...

    STTR Phase I 2017 Department of DefenseArmy
  9. Blood-based diagnostics for Alzheimer's Disease

    SBC: Amprion, Inc.            Topic: NIA

    DESCRIPTION provided by applicant This proposal is for a phase I II fast track project for the STTR program with the main goal to develop a blood test for Alzheimerandapos s disease AD diagnosis AD is the most common dementia in the elderly population and one of the leading causes of death in the developed world One of the main problems in AD is the lack of an early sensitive and objective ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Developing an automated yeast dissection system for aging research

    SBC: Innovative BioChips LLC            Topic: NIA

    Project Summary Developing an Automated Yeast Dissection System for Aging Research Aging is the single greatest risk factor for diseases that are principal causes of mortality The objectives of aging research are to discover key genes and pathways related to aging that may eventually contribute to retardation of aging and a delay in the onset of age associated diseases The budding yeast Sacchar ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
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