Award Data

NARRATIVE This STTR Phase I proposal details the rationale and the research plan for the development of a novel liquid embolizing agent composed of the genetically engineered protein polymerSELPsilk elastinlike proteinKto embolize cerebral aneurysmsThe SELP embolic would reduce the risk of aneurysm rupture while minimizing the risk of recanalization after treatment and providing a platform for del ...

We propose to develop a set of multiscale modeling tools for structural reactive materials (SRMs) that explicitly treat microscale, mesoscale and macroscale coupling of mechanical response, thermal properties and chemical reactions. At the macroscale, a combined material point method (MPM, solid)/Eulerian (ICE, fluid) methodology, MPM-ICE, will be employed to investigate the behavior of select int ...

This Phase II STTR effort is focused on generating the data necessary to identify the phenomenology that produces carbon deposition within kerosene film cooled rocket engines.This data is essential to guide the model development and validation process.Program outputs will be both data and a physics-based model for carbon deposition.

HiFunda will develop a novel joining technology to enable integration of key technologies such as supercritical CO2 cycles that can significantly increase efficiencies and reduce power system size and cost. The technology platform developed will find application across a broad range of industrial sectors resulting in improved energy efficiency and economics for power systems based on coal and natu ...

Project Summary Identifying disease causing genetic variants is a complex process that requires experts from multiple fields including bioinformatics IT systems administration and disease pathology to work closely together The size of sequencing data files also adds the requirement for large computational resources As a result performing genomic analyses is an ...

Project Summary Atrophic dry age related macular degeneration AMD is the leading cause of severe loss of vision for those over age Dietary supplements containing lutein and zeaxanthin are recommended by the NEI for those at risk of late AMD There has been a corresponding growth in demand for these two xanthophylls Lutein and zeaxanthin are currently sourced from marigolds grown mostl ...

Space platforms are complex dynamical systems and there are many reasons to model them from ground telescope imagery as well as from space-based sensor platforms. One key motivation is to determine the operational state and configuration of the vehicle. Key questions such as did the solar panels fail to deploy, did the object begin to tumble unexpectedly may be addressed by a sufficiently detaile ...

Logistical shortages of ammonia, coupled with the high cost of new manufacturing plants, >$2BB, leads to lower agricultural output and lost revenue. The current Haber-Bosch process is also energy intensive and consumes ~1% of the total world energy output. Fulcrum Biosciences, FBS, with the University of Utah as subcontractor will develop a bio-electrochemical process that converts air into ammoni ...

Gray cast iron piping is the most common pipe material in North America. Based on the high carbon content, graphitic needles or flakes are a common feature in these alloys. As a result, these areas of super-saturated carbon will consistently establish galvanic attack of the adjacent iron matrix, especially when in the presence of most ionic liquids. The localized galvanic potentials create microsc ...

In recent decades, High Performance Computing (HPC) has risen as one of the key enablers of innovation in science and engineering. However, industrial adoption has been impeded by the complexity and cost of deploying applications. Problems include the quality, speed, and flexibility of software tools and the specialized expertise required to adapt solutions given the profusion of hardware config ...