Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Galectin 1: A novel small protein therapy for Duchenne muscular dystrophy

    SBC: STRYKAGEN CORPORATION            Topic: NIAMS

    DESCRIPTION provided by applicant Duchenne Muscular Dystrophy DMD is a fatal muscle disease affecting in every male births DMD results from mutations in the gene encoding the dystrophin a kDa scaffolding protein responsible for providing a mechanical link between the muscle fiber actin cytoskeleton and a transmembrane protein complex called the dystrophin associated glycoprotein ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Optimization of an integrin enhancing molecule for the treatment of Duchenne muscular dystrophy

    SBC: STRYKAGEN CORPORATION            Topic: NIAMS

    DESCRIPTION provided by applicant Duchenne muscular dystrophy is caused by mutations in the dystrophin gene resulting in the loss of the dystrophin glycoprotein complex in skeletal muscle Loss of dystrophin results in reduced sarcolemmal integrity progressive muscle damage and compromised muscle function There is currently no cure and limited treatment options for DMD and all affected child ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  3. Identification of Borrelia burgdorferi diagnostic biomarkers in humans and nonhum

    SBC: DxDiscovery Incorporated            Topic: NIAID

    DESCRIPTION provided by applicant The number of Lyme disease cases in the US has been recently estimated by the CDC at cases year This is major public health concern Currently available diagnostics rely on detection of the antibody response serology to Borrelia burgdorferi the causative agent of Lyme disease However serological tests are not accurate during the early stages of Ly ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Biocatalytic production of precursors to lutein and zeaxanthin to address age related macular degeneration

    SBC: EscaZyme Biochemicals, LLC            Topic: N

    Project Summary Atrophic dry age related macular degeneration AMD is the leading cause of severe loss of vision for those over age Dietary supplements containing lutein and zeaxanthin are recommended by the NEI for those at risk of late AMD There has been a corresponding growth in demand for these two xanthophylls Lutein and zeaxanthin are currently sourced from marigolds grown mostl ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Autonomous Broad Spectrum Environmental Sentinels

    SBC: Nevada Nanotech Systems Inc.            Topic: A13AT017

    We propose a platform for aerial environmental monitoring based on the integration of two advanced technologies for the first time: a lightweight, flying robotic platform capable of hovering and swarming, and a compact, low-power chemical sensor platform called the Molecular Property Spectrometer (MPS): a robust, low-cost, silicon-chip-based micro-electro-mechanical system (MEMS) that has been use ...

    STTR Phase I 2014 Department of DefenseArmy
  6. Sensitive and Shape-Specific Molecular Identification

    SBC: RYON TECHNOLOGIES, INC            Topic: A11aT017

    The ability to rapidly detect, identify and monitor chemical agents remains a challenge of significant importance to the Armed Forces. Existing chemical sensing techniques have shortcomings that inhibit widespread implementation. To address this situation, Ryon Technologies is developing a portable instrument that is based on Rydberg Fingerprint Spectroscopy (RFS) in combination with mass spectrom ...

    STTR Phase II 2014 Department of DefenseArmy
  7. Development of Safe, Reliable, and Durable Lithium-ion Battery for Naval Aircraft Applications

    SBC: Yardney Technical Products, Inc.            Topic: N14AT006

    Yardney will design and develop a lightweight, safe, reliable, and cost-effective aircraft battery with improved thermal design and the use of active cooling techniques. As a novel part of the battery design, Yardney will investigate and implement high performance electrodes using three dimensional (3D) micro-porous current collectors, safer thin metal case cell design, a micro-channel heat pipe t ...

    STTR Phase I 2014 Department of DefenseNavy
  8. Prediction and Measurement of the Carbon Build-Up in Film-Cooled Rocket Engines

    SBC: SIERRA ENGINEERING, INC.            Topic: AF15AT21

    ABSTRACT: Sierra Engineering Inc. (Sierra) believes that existing chemical kinetic models can be efficiently incorporated into commercial CFD codes to predict the mixing, pyrolysis, soot formation and carbon deposition within film cooled rocket engines. During this Phase I STTR effort we will demonstrate that this analysis capability is practical and that we can generate appropriate model validati ...

    STTR Phase I 2015 Department of DefenseAir Force
  9. Lithium Ion / Super Capacitor Hybrid System

    SBC: Electro Standards Laboratory, Inc.            Topic: A15AT010

    A hybrid lithium ion battery / super capacitor energy storage device is developed that uses the high power capability of the super capacitor to satisfy pulsed power load requirements such that stress on the lithium ion batteries is reduced. This results in extended discharge time and higher efficiency utilization of the battery stack.

    STTR Phase I 2015 Department of DefenseArmy
  10. Experimental Noise Measurement System for Ship Sonar Design

    SBC: Btech Acoustics, LLC            Topic: N15AT015

    We propose to develop an acoustic and vibration noise monitoring system for investigating navy ship noise. BTech will explore the different vector sensor technologies, packaging, data recording, mounting, and noise software analysis.

    STTR Phase I 2015 Department of DefenseNavy
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