Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. A NOVEL TARGETED DELIVERY SYSTEM FOR CANCER TREATMENT AND DIAGNOSIS

    SBC: EnduRx Pharmaceuticals Inc.            Topic: NCI

    DESCRIPTION (provided by applicant): Glioblastoma multiforme (GBM) or glioblastoma, is the most common and aggressive malignant primary brain tumor in humans. An effective treatment that increases patient survival would represent a significant advance inthe field, and provide a desperately needed new therapy for this deadly disease. EnduRx is focused on the development of new, targeted systems f ...

    SBIR Phase I 2014 Department of Health and Human Services
  2. A Pintle-Free Divert and Attitude Control System

    SBC: Digital Solid State Propulsion, Inc            Topic: AF141137

    ABSTRACT: Digital Solid State Propulsion is proposing to develop a Divert and Attitude Control System (DACS) for tactical air superiority missiles, using proprietary Electric Solid Propellants (ESPs). Unlike conventional propellants, ESPs can be ignited with electric power applied through inert electrodes within the propellant grain itself, while also maintaining a higher level of insensitivity. ...

    SBIR Phase I 2014 Department of DefenseAir Force
  3. Bayesian Inference of Spacecraft Geometry and Pose

    SBC: VISION SYSTEMS INC.            Topic: AF17AT007

    Space platforms are complex dynamical systems and there are many reasons to model them from ground telescope imagery as well as from space-based sensor platforms. One key motivation is to determine the operational state and configuration of the vehicle. Key questions such as did the solar panels fail to deploy, did the object begin to tumble unexpectedly may be addressed by a sufficiently detaile ...

    STTR Phase I 2017 Department of DefenseAir Force
  4. Biocatalytic production of precursors to lutein and zeaxanthin to address age related macular degeneration

    SBC: EscaZyme Biochemicals, LLC            Topic: N

    Project Summary Atrophic dry age related macular degeneration AMD is the leading cause of severe loss of vision for those over age Dietary supplements containing lutein and zeaxanthin are recommended by the NEI for those at risk of late AMD There has been a corresponding growth in demand for these two xanthophylls Lutein and zeaxanthin are currently sourced from marigolds grown mostl ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Calcaftor, a CFTR stabilizer for Cystic Fibrosis treatment

    SBC: Calista Therapeutics, Inc.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Calista Therapeutics has invented Calcaftor, a first-in-class peptide drug that can treat all Cystic Fibrosis (CF) patients. Calcaftor is validated in the gold standard pre-clinical model of CF using F508 -CFTR lung tissue harvested from CF transplant patients. Results from this model demonstrated a gt25 hour duration of action that enables once daily inhaled n ...

    SBIR Phase I 2014 Department of Health and Human Services
  6. Developing Testing and Validating a Wearable Alcohol Biosensor

    SBC: Clinitech, LLC            Topic: 450

    PROJECT SUMMARY This application for a Phase I SBIR award represents a collaboration between Clinitech LLC and McLean Hospital Harvard Medical School to develop a wearable biosensor for detecting alcohol in the interstitial fluid of humans who have consumed alcohol Excessive use of alcohol accounts for much of the public health burden related to alcohol use disorders including fetal ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Electrically Responsive Energetics for Variable Yield Weapons

    SBC: Digital Solid State Propulsion, Inc            Topic: AF141145

    ABSTRACT: Digital Solid State Propulsion is proposing to develop an Electrically Variable Explosive (EVE) which, through direct electrical control, will provide on-demand sensitization and throttling for enhanced energy output in explosive fills. EVEs are based upon DSSP"s Electric Solid Propellant (ESP) Technology which has demonstrated modified burning rates with electrical input, on/off operat ...

    SBIR Phase I 2014 Department of DefenseAir Force
  8. Electrically Responsive Energetics for Variable Yield Weapons

    SBC: Digital Solid State Propulsion, Inc            Topic: AF141145

    ABSTRACT:This Phase II SBIR is the continuation of DSSPs Phase I work into the development of their novel solid state energetic material into an extremely insensitive, non-toxic, and electrically controllable explosive as a replacement for current Mk 82/83/84 bomb fills. This additional insensitivity does not sacrifice performance, as chemical performance modeling shows that an aluminized version ...

    SBIR Phase II 2015 Department of DefenseAir Force
  9. Evidence-Based Pain Intervention for Veterans: Leveraging Mobile & Social Media

    SBC: Pro-Change Behavior Systems Inc            Topic: NCCIH

    Chronic musculoskeletal pain creates a significant public health burdenand Veterans are disproportionately affectedThe frequency and extent of co occurrence of pain and PTSDpain and Traumatic Brain InjuryTBIall three conditionsPost deployment Multi symptom DisorderPMDand other multi symptom syndromes can complicate and reduce the effectiveness of pain treatmentFurthermorethe majority of Veterans d ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Galectin 1: A novel small protein therapy for Duchenne muscular dystrophy

    SBC: STRYKAGEN CORPORATION            Topic: NIAMS

    DESCRIPTION provided by applicant Duchenne Muscular Dystrophy DMD is a fatal muscle disease affecting in every male births DMD results from mutations in the gene encoding the dystrophin a kDa scaffolding protein responsible for providing a mechanical link between the muscle fiber actin cytoskeleton and a transmembrane protein complex called the dystrophin associated glycoprotein ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
US Flag An Official Website of the United States Government