Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Galectin 1: A novel small protein therapy for Duchenne muscular dystrophy

    SBC: STRYKAGEN CORPORATION            Topic: NIAMS

    DESCRIPTION provided by applicant Duchenne Muscular Dystrophy DMD is a fatal muscle disease affecting in every male births DMD results from mutations in the gene encoding the dystrophin a kDa scaffolding protein responsible for providing a mechanical link between the muscle fiber actin cytoskeleton and a transmembrane protein complex called the dystrophin associated glycoprotein ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Optimization of an integrin enhancing molecule for the treatment of Duchenne muscular dystrophy

    SBC: STRYKAGEN CORPORATION            Topic: NIAMS

    DESCRIPTION provided by applicant Duchenne muscular dystrophy is caused by mutations in the dystrophin gene resulting in the loss of the dystrophin glycoprotein complex in skeletal muscle Loss of dystrophin results in reduced sarcolemmal integrity progressive muscle damage and compromised muscle function There is currently no cure and limited treatment options for DMD and all affected child ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  3. Identification of Borrelia burgdorferi diagnostic biomarkers in humans and nonhum

    SBC: DxDiscovery Incorporated            Topic: NIAID

    DESCRIPTION provided by applicant The number of Lyme disease cases in the US has been recently estimated by the CDC at cases year This is major public health concern Currently available diagnostics rely on detection of the antibody response serology to Borrelia burgdorferi the causative agent of Lyme disease However serological tests are not accurate during the early stages of Ly ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Biocatalytic production of precursors to lutein and zeaxanthin to address age related macular degeneration

    SBC: EscaZyme Biochemicals, LLC            Topic: N

    Project Summary Atrophic dry age related macular degeneration AMD is the leading cause of severe loss of vision for those over age Dietary supplements containing lutein and zeaxanthin are recommended by the NEI for those at risk of late AMD There has been a corresponding growth in demand for these two xanthophylls Lutein and zeaxanthin are currently sourced from marigolds grown mostl ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Roboglasses electronic travel aid with hands free obstacle avoidance for blind and vision impaired users

    SBC: FAUXSEE INNOVATIONS LLC            Topic: N

    Project Summary Fauxsee Innovations LLC The objective of this project is to assess the efficacy and usability of an electronic travel aid ETA called Roboglasses developed through an NSF SBIR grant in reducing head and upper body injuries sustained by blind people who currently use a cane and or guide dog for mobility Canes and dogs only provide information about ground level obstructions ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Noninvasive Home Assessment of Cardiac Filling Pressure to Identify Heart Failure Patients at High Risk for Readmission

    SBC: Vixiar Medical, Inc            Topic: NHLBI

    Congestive heart failure CHF is the most common reason for hospitalization in the U S with over million admissions per year Patients admitted with CHF usually need IV diuretics to promote fluid removal The readmission rate is high over by days and by days post discharge This also presents an enormous economic burden hospitalizations account for a large percentage of the ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Low-Latency Embedded Vision Processor (LLEVS)

    SBC: Nanowatt Design, Inc            Topic: AF15AT13

    ABSTRACT: The goal of head-worn display systems is to increase situation awareness and reduce operator workload. The urgent need is for higher image resolution and lower system latency, while meeting constraints on head-borne weight and power. Current processor solutions cannot meet increased requirements. The challenge is that power consumption is proportional to the amount of data being handled, ...

    STTR Phase I 2015 Department of DefenseAir Force
  8. Prediction and Measurement of the Carbon Build-Up in Film-Cooled Rocket Engines

    SBC: SIERRA ENGINEERING, INC.            Topic: AF15AT21

    ABSTRACT: Sierra Engineering Inc. (Sierra) believes that existing chemical kinetic models can be efficiently incorporated into commercial CFD codes to predict the mixing, pyrolysis, soot formation and carbon deposition within film cooled rocket engines. During this Phase I STTR effort we will demonstrate that this analysis capability is practical and that we can generate appropriate model validati ...

    STTR Phase I 2015 Department of DefenseAir Force
  9. Packaging and Assemblies for High-temperature Intelligent Aerospace Controls

    SBC: OZARK INTEGRATED CIRCUITS, INC.            Topic: AF16AT17

    Continuing from the success of the Phase I project to develop a low-cost, fast-turnaround platform for extreme environments (temperatures >200 Celsius, high vibration), this Phase II project will demonstrate this platform in a real-world application for distributed engine control. To get a meaningful functioning platform as soon as possible, the Smart Sensing Node from the Air Force-commissioned D ...

    STTR Phase II 2017 Department of DefenseAir Force
  10. Prediction and Measurement of the Soot Build-Up in Film-Cooled Rocket Engines

    SBC: JOHNSON ROCKETS            Topic: AF15AT21

    This Phase II STTR effort is focused on generating the data necessary to identify the phenomenology that produces carbon deposition within kerosene film cooled rocket engines.This data is essential to guide the model development and validation process.Program outputs will be both data and a physics-based model for carbon deposition.

    STTR Phase II 2017 Department of DefenseAir Force
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