Award Data

Abstract The use of writing to interact with others is of critical importance to persons with severe physical impairments SPI and persons with severe speech and physical impairments SSPI For these people written communication tools such as email texting and social media play essential roles in supporting social closeness the exchange of information with others and exercising self determi ...

DESCRIPTION provided by applicant This Small Business Innovative Research Phase I project outlines steps to design and optimize a multiplex panel based on the FDA approved Luminex platform which will distinguish systemic juvenile idiopathic arthritis sJIA from other febrile illnesses Ascendant Dx is obtaining exclusive license to a protein biomarker panel which preliminary data indicat ...

DESCRIPTION provided by applicant This SBIR Phase I project seeks to develop a proof of concept for an integrated system for rapid screening of foodborne pathogens in a sample in answer out format The proposed system is based on integration of patented sample preparation technology and patent pending self contained microfluidic assay cartridge technology The Phase I study will focus on detec ...

DESCRIPTION (provided by applicant): Glioblastoma multiforme (GBM) or glioblastoma, is the most common and aggressive malignant primary brain tumor in humans. An effective treatment that increases patient survival would represent a significant advance inthe field, and provide a desperately needed new therapy for this deadly disease. EnduRx is focused on the development of new, targeted systems f ...

DESCRIPTION (provided by applicant): There are currently mutations in over 200 genes that have been described to cause kidney disease. Current strategies for diagnosis of genetic kidney disease are extremely costly and time consuming. We aim to develop a comprehensive next generation sequencing panel that can simultaneously test for all currently described kidney- associated gene mutations at a lo ...

ABSTRACT: Digital Solid State Propulsion is proposing to develop a Divert and Attitude Control System (DACS) for tactical air superiority missiles, using proprietary Electric Solid Propellants (ESPs). Unlike conventional propellants, ESPs can be ignited with electric power applied through inert electrodes within the propellant grain itself, while also maintaining a higher level of insensitivity. ...

DESCRIPTION (provided by applicant): This Small Business Innovation Research Phase I project will investigate the technical feasibility of an in vitro excystation-based automated cartridge assay for rapid detection of viable Cryptosporidium oocysts in water. Briefly, viable oocysts will be subjected to an in vitro excystation step to release sporozoites and the antigens for detection on a patent-p ...

DESCRIPTION provided by applicant Wheelchairs in the modern form have been around since at least when John Joseph Merlin invented pushrim propulsion The Merlin Chair as it was called bears a remarkable resemblance to wheelchairs today despite the intervening years The conventional pushrim operated wheelchair has become the prevalent assistive care mobility device because of its ...

Space platforms are complex dynamical systems and there are many reasons to model them from ground telescope imagery as well as from space-based sensor platforms. One key motivation is to determine the operational state and configuration of the vehicle. Key questions such as did the solar panels fail to deploy, did the object begin to tumble unexpectedly may be addressed by a sufficiently detaile ...

Project Summary Atrophic dry age related macular degeneration AMD is the leading cause of severe loss of vision for those over age Dietary supplements containing lutein and zeaxanthin are recommended by the NEI for those at risk of late AMD There has been a corresponding growth in demand for these two xanthophylls Lutein and zeaxanthin are currently sourced from marigolds grown mostl ...