Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Multi-Blot Western Device

    SBC: YC BIOELECTRIC LLC            Topic: NIGMS

    DESCRIPTION (provided by applicant): The long-term objective of this STTR project is to commercialize the protein multi-blot Western device, which contributes to improving the productivity and accuracy of conventional Western blot analysis. Although Western blotting has been used for more than three decades, this labor-and-cost demanding technique remains a key routine for a majority of life scien ...

    STTR Phase I 2014 Department of Health and Human Services
  2. The Emotion Builder: An Intervention for Emotional Deficits after Brain Injury

    SBC: EMOTED, INC.            Topic: NICHD

    DESCRIPTION (provided by applicant): People with traumatic brain injury (TBI) are often plagued with socio-emotional deficits that include difficulty identifying emotions in oneself (alexithymia), difficulty recognizing other peoples' emotions (impaired affect recognition), and empathy loss. These highly prevalent deficits, ranging between 39-70% of the moderate to severe TBI population, are ...

    STTR Phase I 2014 Department of Health and Human Services
  3. Sympathetic Nerve Activity Recorded From the Skin and Cardiac Arrhythmias

    SBC: ARRHYTHMOTECH            Topic: NHLBI

    DESCRIPTION (provided by applicant): The broad and long-term objective of this research project is to use, develop and market an instrument for the simultaneous recording of sympathetic nerve activity (SNA) and electrocardiogram (ECG) using electrodes on the skin. This method (neuECG) was discovered in Dr. Chen's research laboratory at the Krannert Institute of Cardiology, and a patent applic ...

    STTR Phase I 2014 Department of Health and Human Services
  4. Novel Silica-Based Organic Polymer for Ambient Ionization Mass Spectrometry

    SBC: Prosolia, Inc.            Topic: NIGMS

    DESCRIPTION provided by applicant Most samples of chemical interest are complex mixtures making the usual combination of chromatography with mass spectrometry MS a natural choice However the increased demand for chemical analysis by mass spectrometry in many areas of science makes it imperative to increase efficiency of analysis by minimizing sample workup and overall analysis time which ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Metal ion-functionalized soluble nanopolymers: A new analytical platform for plas

    SBC: Tymora Analytical Operations, LLC            Topic: 300

    DESCRIPTION provided by applicant Mass spectrometry based proteomics is an emerging technology that has seen possible applications everywhere The technique can potentially use one drop of our blood to reveal onset and progress of diseases Current Randamp D using plasma serum proteome sample sets however is severely limited by the high complexity and dynamic range of protein concentrations ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Lowering the Cost of Imaging for Retinal Microvasculature in Diabetic Patients

    SBC: AEON IMAGING, LLC            Topic: W

    DESCRIPTION provided by applicant Recently we found extensive remodeling of the microvasculature of the retina occurring in some diabetic patients much earlier than expected This provides the potential for novel biomarkers However the equipment is too expensive for most clinics and small practices These early retinal microvascular changes cannot be seen with routine clinical examination o ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  7. Discovery of Oligodendrocyte Stimulators

    SBC: Medosome Biotec, LLC            Topic: 101

    DESCRIPTION provided by applicant Up to of low birth weight preterm infants manifest some form of periventricular white matter injury PWMI making it the most common form of brain injury affecting premature infants In the US infants per year are born at risk for PWMI and about children per year will develop PWMI World wide infants will be born each year at ri ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  8. Galectin 1: A novel small protein therapy for Duchenne muscular dystrophy

    SBC: STRYKAGEN CORPORATION            Topic: NIAMS

    DESCRIPTION provided by applicant Duchenne Muscular Dystrophy DMD is a fatal muscle disease affecting in every male births DMD results from mutations in the gene encoding the dystrophin a kDa scaffolding protein responsible for providing a mechanical link between the muscle fiber actin cytoskeleton and a transmembrane protein complex called the dystrophin associated glycoprotein ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Optimization of an integrin enhancing molecule for the treatment of Duchenne muscular dystrophy

    SBC: STRYKAGEN CORPORATION            Topic: NIAMS

    DESCRIPTION provided by applicant Duchenne muscular dystrophy is caused by mutations in the dystrophin gene resulting in the loss of the dystrophin glycoprotein complex in skeletal muscle Loss of dystrophin results in reduced sarcolemmal integrity progressive muscle damage and compromised muscle function There is currently no cure and limited treatment options for DMD and all affected child ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Universal amplifier system for high-fidelity multi-modal biosignal recordings

    SBC: REFER2INPUT, LLC            Topic: 213

    DESCRIPTION provided by applicant The measurement monitoring and use of bioelectric signals has evolved from the measurement of the electrical activity of the heart to encompass tissues ranging from cardiac skeletal and smooth muscles to brain and peripheral nerve tissues Together with this development has been the evolution of specialized equipment to capture and interpret these minute sig ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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