Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Transdermal H2S Sensing Device for Monitoring Peripheral Artery Disease

    SBC: EXHALIX, LLC            Topic: NHLBI

    Project Summary/Abstract The proposed effort addresses an unmet need for early diagnosis of peripheral artery disease (PAD). PAD is a disorder of vascular circulation that affects more than 8 million Americans, most of whom are unaware of its existence, risks, and threats. PAD is caused primarily by plaque-induced atherosclerosis and in some instances by blood vessel inflammation, stenosis, and in ...

    STTR Phase I 2014 Department of Health and Human Services
  2. Galectin 1: A novel small protein therapy for Duchenne muscular dystrophy

    SBC: STRYKAGEN CORPORATION            Topic: NIAMS

    DESCRIPTION provided by applicant Duchenne Muscular Dystrophy DMD is a fatal muscle disease affecting in every male births DMD results from mutations in the gene encoding the dystrophin a kDa scaffolding protein responsible for providing a mechanical link between the muscle fiber actin cytoskeleton and a transmembrane protein complex called the dystrophin associated glycoprotein ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Optimization of an integrin enhancing molecule for the treatment of Duchenne muscular dystrophy

    SBC: STRYKAGEN CORPORATION            Topic: NIAMS

    DESCRIPTION provided by applicant Duchenne muscular dystrophy is caused by mutations in the dystrophin gene resulting in the loss of the dystrophin glycoprotein complex in skeletal muscle Loss of dystrophin results in reduced sarcolemmal integrity progressive muscle damage and compromised muscle function There is currently no cure and limited treatment options for DMD and all affected child ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  4. Identification of Borrelia burgdorferi diagnostic biomarkers in humans and nonhum

    SBC: DxDiscovery Incorporated            Topic: NIAID

    DESCRIPTION provided by applicant The number of Lyme disease cases in the US has been recently estimated by the CDC at cases year This is major public health concern Currently available diagnostics rely on detection of the antibody response serology to Borrelia burgdorferi the causative agent of Lyme disease However serological tests are not accurate during the early stages of Ly ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Development, Usability Testing, and Effectiveness Evaluation of the Wraparou

    SBC: ACCOUNTABILITY SOLUTIONS, INC.            Topic: 104

    DESCRIPTION provided by applicant The purpose of this Phase II Small Business Technology Transfer STTR project is to complete development and evaluate usability and effectiveness of the Wraparound Team Monitoring System Wrap TMS a web based electronic behavioral health information system EBHIS for the most widely implemented care coordination model in childrenandapos s behavioral healt ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Biocatalytic production of precursors to lutein and zeaxanthin to address age related macular degeneration

    SBC: EscaZyme Biochemicals, LLC            Topic: N

    Project Summary Atrophic dry age related macular degeneration AMD is the leading cause of severe loss of vision for those over age Dietary supplements containing lutein and zeaxanthin are recommended by the NEI for those at risk of late AMD There has been a corresponding growth in demand for these two xanthophylls Lutein and zeaxanthin are currently sourced from marigolds grown mostl ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Prediction and Measurement of the Carbon Build-Up in Film-Cooled Rocket Engines

    SBC: SIERRA ENGINEERING, INC.            Topic: AF15AT21

    ABSTRACT: Sierra Engineering Inc. (Sierra) believes that existing chemical kinetic models can be efficiently incorporated into commercial CFD codes to predict the mixing, pyrolysis, soot formation and carbon deposition within film cooled rocket engines. During this Phase I STTR effort we will demonstrate that this analysis capability is practical and that we can generate appropriate model validati ...

    STTR Phase I 2015 Department of DefenseAir Force
  8. Surface Deformation Measurements Using Light Modulation Imaging

    SBC: Southwest Sciences, Inc.            Topic: AF15AT38

    ABSTRACT: Hypersonic vehicles will require structures that can withstand highly transient flows and complex loadings throughout the flight trajectory. Shock boundary-layer interaction can excite panels locally and lead to structural failures. Non-contacting measurement technologies are needed to characterize the effect of flow transients (due to pressure and temperature fluctuations) on the struct ...

    STTR Phase I 2015 Department of DefenseAir Force
  9. Impact of Hypersonic Flight Environment on Electro-Optic/Infrared (EO/IR) Sensors

    SBC: MZA Associates Corporation            Topic: AF15AT40

    ABSTRACT: MZA partnered with the University of Notre Dame proposes to extend MZAs WaveTrain wave-optics sensor simulation framework to model EO/IR sensors operating on hypersonic aircraft. Following the methods we have developed for aero-optical imaging through subsonic, transonic, and supersonic flows, existing WaveTrain libraries will be expanded to include hypersonic flow, shocks, thermal effec ...

    STTR Phase I 2015 Department of DefenseAir Force
  10. Protection of DoD Satellite Communications Against RF Interferences and Personal Mobile Telecommunications

    SBC: TAU TECHNOLOGIES LLC            Topic: AF14AT17

    ABSTRACT: The United States relies heavily on force multiplying, space-based navigation, communications and intelligence, surveillance and reconnaissance (ISR) capabilities. These satellites populate all orbital regimes including low-earth orbit (LEO), medium earth orbit (MEO) and geosynchronous earth orbit (GEO) and frequently require complex ground station network support requirements. Miltary ...

    STTR Phase I 2015 Department of DefenseAir Force
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