Award Data

Bird-aircraft collisions (birdstrikes) present a significant threat to military and commercial aircraft, and as bird populations and air traffic continue to grow, and airport/airbase operations continue to expand, the problem will steadily get worse. A majority of the efforts to solve this problem focus specifically on bird mitigation via, e.g., wildlife and environmental management. However, a ke ...

Distributed systems, important to civilian and military infrastucture, have steadily become more complex and steadily more difficult to understand, implement, and maintain. Addressing these dangers, a collaboration between ATC-NY and Cornell University will build a mathematically based tool, SCorES, providing powerful automated support for specifying, developing, verifying, and synthesizing re ...

DESCRIPTION (provided by applicant): The overall goal of the proposal is to develop an automated data acquisition system for non-invasive quantitative cancer detection, screening, and monitoring, based on highly sensitive low volume real time PCR technique and capillary electrophoresis, apply this system for quantitative analysis of the telomerase activity and gene expression in single cancer c ...

DESCRIPTION (provided by applicant): About 250,000 Americans a year die of coronary heart disease without being hospitalized, and most of these are sudden deaths caused by cardiac arrest. Due to similarities of cardiovascular physiology and genetic structure to humans, biomedical research has increasingly employed the mouse in models of human disease, which has provided powerful tools for investig ...

Clear Science Corp. and the University of Minnesota propose to evaluate and develop design optimization methods that exploit flow ionization associated with hypersonic, trans-atmospheric flight vehicles. Using magnetic fields from on-board devices, power may be extracted from ionized gas generated in the high-energy flow and electromagnetic forces can control heating and aerodynamic loading on th ...

DESCRIPTION (provided by applicant): Phase I: It has become increasingly clear that the metastatic potential of solid cancer best correlates with the nature of the cells emigrating from the primary tumors. These emigrating cells enter the circulatory system and thus can readily be recovered using a simple and minimally invasive procedure. However, molecular analysis of these cells remains technic ...

DESCRIPTION (provided by applicant): The goal of this project is to produce "humanized" livers in large animal models such as sheep and pigs that can serve as a reliable source of significant numbers of functional human hepatocytes. The isolated human hepatocytes and/or "humanized" livers can be used for drug toxicity studies as well as for possible clinical use in patients with liver failure. Tra ...

DESCRIPTION (provided by applicant): The goal of this Phase II STTR proposal is to develop a freely available, open-source software toolkit for image-guided surgery. This proposal is a partnership between a university-based biomedical research group (Imaging Science and Information Systems [ISIS] Center, Department of Radiology, Georgetown University) and a small business specializing in open-s ...

DESCRIPTION (provided by applicant): Quantum leaps in medicine and the biological sciences will be achieved when anatomical and functional details at multiple scales can be linked within and across subjects. The technology for capturing, managing, and reporting such details and linkages is the science of atlas formation. While images have the potential to capture micro and macro details, a ...

DESCRIPTION (provided by applicant): Phase I Reflectance confocal microscopy images the cellular and structural morphology of tissue in-vivo or ex-vivo without the need for histological processing. Existing reflectance confocal microscopes use single wavelength laser to generate gray scale intensity images. The goals of this proposal are to build and characterize a coherence reflectance c ...