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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Biocatalytic production of precursors to lutein and zeaxanthin to address age related macular degeneration

    SBC: EscaZyme Biochemicals, LLC            Topic: N

    Project Summary Atrophic dry age related macular degeneration AMD is the leading cause of severe loss of vision for those over age Dietary supplements containing lutein and zeaxanthin are recommended by the NEI for those at risk of late AMD There has been a corresponding growth in demand for these two xanthophylls Lutein and zeaxanthin are currently sourced from marigolds grown mostl ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Novel Antigen-Specific Immunomodulatory Tregitope-based Therapy to Address Autoimmune Pathogenesis in Graves' Disease

    SBC: EPIVAX, INC.            Topic: 200

    ABSTRACT SignificanceGravesdiseaseGDone of the most prevalent autoimmune diseasesis caused by stimulating autoantibodiesTSAbto the Thyroid Stimulating Hormone ReceptorTSHRresulting in hyperthyroidismCurrent methods for managing hyperthyroidism in GD target excess thyroid hormone secretion by ablation or removal of the thyroid or by blocking thyroid hormone synthesisEach of these therapies is assoc ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Patient Engagement Alcohol Risk Reduction System PEARRS

    SBC: VERMEDX, INC.            Topic: 450

    PROJECT SUMMARY ABSTRACT Over a quarter of primary care patients in the United States can be classified as unhealthy drinkers because their alcohol use conveys a high risk of health and social consequences Unfortunately unhealthy drinking is under recognized in spite of the existence of valid screening tools Even when unhealthy drinking is recognized barriers such as provider discomfort shor ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Developing Testing and Validating a Wearable Alcohol Biosensor

    SBC: Clinitech, LLC            Topic: 450

    PROJECT SUMMARY This application for a Phase I SBIR award represents a collaboration between Clinitech LLC and McLean Hospital Harvard Medical School to develop a wearable biosensor for detecting alcohol in the interstitial fluid of humans who have consumed alcohol Excessive use of alcohol accounts for much of the public health burden related to alcohol use disorders including fetal ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Fast Optical Limiters (OL) with Enhanced Dynamic Range

    SBC: ADVANCED PHOTON SCIENCES LLC            Topic: AF17AT029

    Optical limiters (OL) protect sensitive optical and electronic devices from laser-induced damage. The existing passive OL utilize nonlinear optical materials transmitting low-intensity light, while blocking laser radiation with intensity exceeding certain limiting threshold (LT). The common problem with the existing OL is that, at any particular frequency range, the choice of suitable nonlinear ...

    STTR Phase I 2017 Department of DefenseAir Force
  6. Bayesian Inference of Spacecraft Geometry and Pose

    SBC: VISION SYSTEMS INC            Topic: AF17AT007

    Space platforms are complex dynamical systems and there are many reasons to model them from ground telescope imagery as well as from space-based sensor platforms. One key motivation is to determine the operational state and configuration of the vehicle. Key questions such as did the solar panels fail to deploy, did the object begin to tumble unexpectedly may be addressed by a sufficiently detaile ...

    STTR Phase I 2017 Department of DefenseAir Force
  7. Synthesis of HAN and HEHN in a Continuous Mix Process

    SBC: Digital Solid State Propulsion, Inc            Topic: AF171061

    Production of hydroxylamine nitrate (HAN) and hydroxyethyl hydrazine nitrate (HEHN) is of great concern for the manufacture of AF-315E. Current stockpiles of heritage ingredients held by AFRL are being depleted and those manufacturers are no longer in exi

    SBIR Phase I 2017 Department of DefenseAir Force
  8. Evaluating the Comparative Validity and Reliability of SERAS A Decision Support Tool for Assessing Near Term Risk of Suicide in Emergency Departments

    SBC: Wiser Systems LLC            Topic: 104

    PROJECT SUMMARY The goal of the NIMH Zero Suicide Initiative is prevention of suicide among individuals being served by health care systems The Products to Support Applied Research Towards Zero Suicide Healthcare Systems FOA specifically calls for development of health IT products designed to meet this goal Our Systematic Expert Risk Assessment of Suicide SERAS is a neural network based dec ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Connecting Cultures and Technology: Addressing Disparities in Mental Health Intervention for Refugees

    SBC: GAMETHEORY, INC            Topic: NIMHD

    DESCRIPTION provided by applicant Thousands of individuals seek refuge in the United States to escape atrocities of war and torture in their country of origin An overwhelming majority of these individuals continue to struggle with Chronic Traumatic Stress CTS the persistence of prior traumatic events e g re experiencing past trauma coupled with daily post migration stressors e g pove ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Galectin 1: A novel small protein therapy for Duchenne muscular dystrophy

    SBC: STRYKAGEN CORPORATION            Topic: NIAMS

    DESCRIPTION provided by applicant Duchenne Muscular Dystrophy DMD is a fatal muscle disease affecting in every male births DMD results from mutations in the gene encoding the dystrophin a kDa scaffolding protein responsible for providing a mechanical link between the muscle fiber actin cytoskeleton and a transmembrane protein complex called the dystrophin associated glycoprotein ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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