Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Application of PPODA QT for embolization of aneurysms

    SBC: Aneuvas Technologies, Inc.            Topic: 101

    A cerebral aneurysm is an abnormal enlargement or pouch that forms from a weakened vessel segment in the brain Often going unnoticed and untreated an aneurysm can cause a sudden and catastrophic hemorrhage or stroke Approximately of patients die from an aneurysm rupture even before receiving medical attention and of patients die despite medical treatment Patients that survive typical ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Regulators of NaV Channels Novel Anti Allodynic Drug Candidates

    SBC: Regulonix            Topic: 102

    PROJECT SUMMARY Chemotherapy induced peripheral neuropathy CIPN is a common prevalence and potentially dose limiting side effect of many cancer chemotherapy drug treatment regimens Clinically CIPN presents with pain that is burning shooting or electric shock like The increase in prevalence of cancer coupled with an increase in the cancer survival rates due to chemotherapy regimens ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Biomimetic Wound Healing Devices to Close Diabetic Wounds

    SBC: Protein Genomics            Topic: NIDDK

    The long term objective of this project is the synthesis and assembly of wound healing devices that mimic as closely as possible the biochemical and mechanical characteristics of healthy human skin The proposed research would focus on the synthesis of membranes containing electrospun human recombinant tropoelastin and collagen mixtures The ratios of the two molecules and the spinning condition ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Biocatalytic production of precursors to lutein and zeaxanthin to address age related macular degeneration

    SBC: EscaZyme Biochemicals, LLC            Topic: N

    Project Summary Atrophic dry age related macular degeneration AMD is the leading cause of severe loss of vision for those over age Dietary supplements containing lutein and zeaxanthin are recommended by the NEI for those at risk of late AMD There has been a corresponding growth in demand for these two xanthophylls Lutein and zeaxanthin are currently sourced from marigolds grown mostl ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Alternative Methods for Creating a Sodium Guidestar

    SBC: Hart Scientific Consulting International LLC            Topic: AF17AT005

    The objective of the proposed research is to demonstrate high-power, scalable, and stable laser sources at specific wavelengths with narrow linewidth matched to the single velocity class of mesospheric atomic sodium for guide star application. The operation at tailored wavelengths, 1141 nm and 1178 nm (for 589 nm via frequency doubling) is addressed by the use of bandgap-engineered optically pumpe ...

    STTR Phase I 2017 Department of DefenseAir Force
  6. Alternative Methods for Creating a Sodium Guidestar

    SBC: TPhotonics Inc.            Topic: AF17AT005

    The purpose of this proposed research is to develop and commercialize a novel two color sodium guidestar laser operating simultaneously at 589 nm and 1141 nm. Our patented T-cavity design combined with VECSEL technology will be the basis for the guidestar development. The polychromatic laser guidestar (PLGS) system being proposed currently does not exist and would allow for the correction of atmos ...

    STTR Phase I 2017 Department of DefenseAir Force
  7. Three-sided Pyramid Wavefront Sensor for High Sensitivity Wavefront Control

    SBC: Hart Scientific Consulting International LLC            Topic: AF17AT006

    Fully develop the analytic theory of wavefront reconstruction from measurements made with a three-sided pyramid wavefront sensor (PWFS3), including the effects of variable modulation, photon and camera noise sources, and object angular extent. Carry out performance predictions of the PWFS3 through numerical modeling. Compare the sensitivity of the PWFS3 to a conventional Shack-Hartmann sensor and ...

    STTR Phase I 2017 Department of DefenseAir Force
  8. Practical Application of Molecular-Scale Modeling to Problems at the Grain Scale and Larger

    SBC: GLOBAL ENGINEERING RESEARCH AND TECHNOLOGIES, LLC            Topic: AF17AT023

    The mechanical testing of energetic materials makes experimentation highly expensive and hazardous. Therefore, an accurate and practical modeling approach is necessary to predict their mechanical properties. Numerous atomistic to continuum models exist to predict the properties of energetic materials. However, these methods are not coupled with each other in a systematic and practical way; thus, ...

    STTR Phase I 2017 Department of DefenseAir Force
  9. FUN3D-based Adjoint Optimization for Elastic Tandem Airfoils in Chaotic Flows

    SBC: Zona Technology, Inc            Topic: AF17AT017

    This proposal develops a two-dimensional, FUN3D-based, flow-structure-coupled adjoint optimization framework capable of handling chaotic dynamics, and validate this framework on an elastic tandem airfoil configuration in chaotic flow. To overcome the challenge of sensitivity analysis in chaotic flows, we will develop in this proposal the adjoint NI-LSS algorithm. This algorithm is the discrete adj ...

    STTR Phase I 2017 Department of DefenseAir Force
  10. Bayesian Inference of Spacecraft Geometry and Pose

    SBC: VISION SYSTEMS INC.            Topic: AF17AT007

    Space platforms are complex dynamical systems and there are many reasons to model them from ground telescope imagery as well as from space-based sensor platforms. One key motivation is to determine the operational state and configuration of the vehicle. Key questions such as did the solar panels fail to deploy, did the object begin to tumble unexpectedly may be addressed by a sufficiently detaile ...

    STTR Phase I 2017 Department of DefenseAir Force
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