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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Therapeutic Administration of Suppressor of Cytokine Signaling Mimetics to Ameliorate Type Diabetes
SBC: ONEVAX, LLC Topic: NIAIDType Diabetes T D results from a breakdown of self tolerance that is characterized by immune cell mediated destruction of the insulin producing cells in the pancreas Ultimately glucose metabolism is interrupted resulting in the development of life threatening complications such as heart disease and renal failure T D affects an estimated million Americans with more than new patie ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Probabilistic Modeling for Software Guided Radiotherapy Patient Plan QA
SBC: SUN NUCLEAR CORP. Topic: 103Errors in the planning and delivery of radiation therapy can result in inferior outcomes for patients The magnitude of this problem is now well appreciated from cooperative group trials and other sources At present however there are few concrete tools to reduce the chance of plan errors passing undetected Current practice uses a variety of error mitigation means such as human inspection of th ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Identification of Small Molecule Amyloid Beta Peptide Reducing Agent
SBC: Smart Biomolecules, Inc. Topic: NIAAlzheimer s disease AD is a multifactorial heterogeneous and enormously complex disorder characterized by progressive intellectual deterioration Although remarkable advances have been made in unraveling the biological basis of the disease in the last two decades that immense knowledge has not been translated in to successful therapy With the failure of secretase inhibitors at the clinical tr ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Biocatalytic production of precursors to lutein and zeaxanthin to address age related macular degeneration
SBC: EscaZyme Biochemicals, LLC Topic: NProject Summary Atrophic dry age related macular degeneration AMD is the leading cause of severe loss of vision for those over age Dietary supplements containing lutein and zeaxanthin are recommended by the NEI for those at risk of late AMD There has been a corresponding growth in demand for these two xanthophylls Lutein and zeaxanthin are currently sourced from marigolds grown mostl ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Developing a novel therapy for diabetic retinopathy
SBC: EVERGLADES BIOPHARMA LLC Topic: WProject Summary Diabetic retinopathy DR is a leading cause of vision loss affecting about million people worldwide A major breakthrough in DR therapy is the recent approval of vascular endothelial growth factor VEGF inhibitors However anti VEGF therapy has limited efficacy with a number of side effects The critical barrier is how to identify other angiogenic targets for alternative or ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
A Randomized Blinded Placebo Controlled Clinical Trial to Evaluate Longeveron Mesenchymal Stem Cell LMSC Therapy for Treating The Metabolic Syndrome
SBC: Longeveron LLC Topic: NIAThe metabolic syndrome MetS is a cluster of factors that increases the risks for cardiovascular disease type diabetes mellitus and mortality and currently affects andgt of US adults MetS is associated with endothelial dysfunction decreased circulating endothelial progenitor cells EPCs and a pro inflammatory state We have made the exciting discovery that therapy with allogeneic me ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Bayesian Inference of Spacecraft Geometry and Pose
SBC: VISION SYSTEMS INC Topic: AF17AT007Space platforms are complex dynamical systems and there are many reasons to model them from ground telescope imagery as well as from space-based sensor platforms. One key motivation is to determine the operational state and configuration of the vehicle. Key questions such as did the solar panels fail to deploy, did the object begin to tumble unexpectedly may be addressed by a sufficiently detaile ...
STTR Phase I 2017 Department of DefenseAir Force -
Development lightmap rendering technology to advance infrared simulation capabilities for training applications
SBC: CORNERSTONE SOFTWARE SOLUTIONS INC Topic: AF17AT012Recent technology advances have enabled the simulation community to achieve greater realism in virtual training environments. As new methods for synthetic image generation are developed, the lack of readily available supporting data to populate these specialized techniques limits their implementation. Currently the capability is not available to efficiently generate enhanced temporal energy maps ...
STTR Phase I 2017 Department of DefenseAir Force -
Plasmonic Metamaterial Approach to Infrared Scene Projection
SBC: TRUVENTIC LLC Topic: AF17AT022Truventic proposes a novel MEMS-based plasmonic infrared scene projector to support hardware-in-the-loop testing of missile seekers, forward looking IR cameras (FLIR), counter measure simulation and tracking systems. The approach avoids known limitations of resistive arrays and provides high dynamic range, unprecedented high apparent temperature, high modulation rates, high pixel to pixel contrast ...
STTR Phase I 2017 Department of DefenseAir Force -
Plasmonic Metamaterial Approach to Infrared Scene Projection
SBC: PLASMONICS INC Topic: AF17AT022As both the response speed and sensitivity of thermal imagers have improved significantly over recent years, new IRSP systems are needed to provide greater dynamic range and faster response speeds. Addressing these issues, as well as producing a cost effective and modular IRSP system will be critical for providing quality scene projection for the next generation of infrared imagers. To address the ...
STTR Phase I 2017 Department of DefenseAir Force