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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Biocatalytic production of precursors to lutein and zeaxanthin to address age related macular degeneration

    SBC: EscaZyme Biochemicals, LLC            Topic: N

    Project Summary Atrophic dry age related macular degeneration AMD is the leading cause of severe loss of vision for those over age Dietary supplements containing lutein and zeaxanthin are recommended by the NEI for those at risk of late AMD There has been a corresponding growth in demand for these two xanthophylls Lutein and zeaxanthin are currently sourced from marigolds grown mostl ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Development of a protein drug for pancreatic cancer treatment

    SBC: ProDa BioTech L.L.C.            Topic: NCI

    Abstract Pancreatic cancers are devastating diseases with five year survival rate less than Currently there is no effective treatment for advanced disease One major barrier to efficacy of anti tumor therapeutics is the dense desmoplastic stromal response Evidence suggests that cancer associated pancreatic stellate cells CAPaSC produce the stromal collagen The ECM laid down by CAPaSC is c ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Monoclonal lamprey VLR antibodies specific for mucin type O linked glycan core structures

    SBC: Novab, Inc.            Topic: 300

    PROJECT SUMMARY We will develop and commercialize to the research community a new class of glycan specific binding reagents that incorporate the recognition function of variable lymphocyte receptors VLRs the antigen receptors of the adaptive immune system of jawless vertebrates lamprey and hagfish Such reagents are essential to detecting localizing quantifying and establishing biological ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Evolution of an Adaptable Prosthetic Foot Design for Normalization of Biomechanics During Community Participation

    SBC: OHIO WILLOW WOOD COMPANY, THE            Topic: NICHD

    Evolution of an Adaptable Prosthetic Foot Design for Normalization of Biomechanics During Community Participation Summary Abstract The vision of this project is to improve the functional physical mobility of people with lower extremity amputations so that they can more fully and confidently participate in a wider range of activities This will enhance their personal satisfaction thereby improving ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Small molecule therapy for metastatic prostate cancer

    SBC: MetCure Therapeutics LLC            Topic: 102

    Enzalutamide resistance is a major obstacle in the treatment of metastatic castration resistant prostate cancer mCRPC Recently we developed a small molecule lead compound GH and demonstrated its potent activity against bone metastatic prostate cancer cells In this Phase I STTR application we hypothesize that GH is a novel lead compound with nanomolar potency against enzalutamide resist ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Bayesian Inference of Spacecraft Geometry and Pose

    SBC: VISION SYSTEMS INC            Topic: AF17AT007

    Space platforms are complex dynamical systems and there are many reasons to model them from ground telescope imagery as well as from space-based sensor platforms. One key motivation is to determine the operational state and configuration of the vehicle. Key questions such as did the solar panels fail to deploy, did the object begin to tumble unexpectedly may be addressed by a sufficiently detaile ...

    STTR Phase I 2017 Department of DefenseAir Force
  7. Target-In-The-Loop Sensing Suite for Long-Range Atmospheric Effects Characterization

    SBC: MV INNOVATIVE TECHNOLOGIES, LLC            Topic: AF17AT008

    This project offers a novel polychromatic target-in-the-loop atmospheric sensing (TILAS) concept for in situ characterization of the combined effects of atmospheric turbulence, refractivity, transmittance, and optical path difference (piston phase) over long-range, low elevation angle atmospheric paths. The proposed concept allows practical implementation of a modular compact TILAS atmospheric sen ...

    STTR Phase I 2017 Department of DefenseAir Force
  8. III-Nitride Ternary Alloy Substrates for Next Generation UV Optoelectronics and Power Electronics

    SBC: Innovative Advanced Materials, Inc.            Topic: AF17AT024

    Innovative Advanced Materials (IAM), Inc., founded by Dr. W. Alan Doolittle, proposes to develop a new generation of bulk synthesis tools operating at significantly higher pressure than current prototype systems which already demonstrate tantalizing material quality and high growth rates with proven alloy and dopant control capability to produce AlGaN substrates with remarkably low cost and high q ...

    STTR Phase I 2017 Department of DefenseAir Force
  9. Fast Response Heat Flux Sensors and Efficient Data Reduction Methodology for Hypersonic Wind Tunnels

    SBC: Ahmic Aerospace LLC            Topic: AF17AT001

    Accurate knowledge of heat flux is critical in assessing the performance and survivability of hypersonic aerodynamic systems. Under these flow regimes extreme pressures, temperatures, and vibrations make it difficult to quantify even the most basic aerothermodynamic properties. Ahmic Aerospace and Virginia Tech propose an innovative new approach to develop robust heat flux sensors and a data reduc ...

    STTR Phase I 2017 Department of DefenseAir Force
  10. AC Plasma Sensor For High Enthalpy Hypersonic Test Facilities

    SBC: SPECTRAL ENERGIES LLC            Topic: AF17AT002

    Spectral Energies and the University of Notre Dame is developing a new class of point-wise sensors for high-enthalpy conditions that rely on the use of a weakly ionized AC discharge between two electrodes as the main sensing element. The advantages of this approach include a native high bandwidth with a theoretical maximum in excess of 15 MHz and a simple mechanical design that is inherently robus ...

    STTR Phase I 2017 Department of DefenseAir Force
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