Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Drug eluting Brachytherapy Implants for Chemo radiation Therapy

    SBC: TheraNano LLC            Topic: 102

    Prostate cancer PCa is the second leading cause of cancer death in American men with deaths and new cases estimated in the US in Radiation therapy is one of the standard therapies for high and intermediate risk patients and is a non surgical therapy option for low risk patients A combined chemo radiation therapy CRT approach has been shown in several trials to improve s ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Neuro Optical Diagnostic System for Macular Degeneration

    SBC: NEUROFIELDZ INC.            Topic: NIA

    Age related macular degeneration AMD causes progressive loss of central vision and is the leading cause of blindness in the developed world A major challenge in the development of effective treatments for AMD is the lack of sensitive practical visual function endpoints People with AMD manifest delayed dark adaptation DA recovery and DA tests are a FDA approved method for diagnosing AMD Cu ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Therapeutic game based exercise during hemodialysis to improve balance and mobility

    SBC: BioSensics LLC            Topic: NIA

    Abstract Chronic kidney disease CKD disproportionately impacts older adults Balance mobility and falls are serious problems for CKD patients due to associated peripheral neuropathy and peripheral arterial disease which also contribute to foot ulcers and other foot problems in this population Among older adults these problems are often compounded by other comorbid conditions leaving older ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Online Practitioner Training in Behavioral Intervention in Autism Skill Training Using an Interactive Simulated Child

    SBC: Praxis            Topic: 104

    Project Summary Autism Spectrum Disorder ASD is a complex neurological disorder that typically appears before the age of three and immediately and profoundly affects a young childandapos s ability to communicate develop language form social relationships and respond appropriately to environmental cues Behavioral intervention is a consensus andquot best practiceandquot scientific treatment me ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Quantitative Non Invasive Brain Imaging using Magnetic Nanoparticles

    SBC: TheraNano LLC            Topic: NIDA

    This Phase I STTR project is based upon a new technique Quantitative Ultra short Time to Echo Contrast Enhanced QUTE CE MRI utilizing UTE sequences with SuperParamagnetic Iron Oxide Nanoparticles SPION that leads to quantifiable vascular images with unprecedented clarity and definition QUTE CE is particularly optimal using Ferumoxytol an FDA approved iron oxide nanopharmaceutical The techni ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. MISSION U A Multimedia Training Tool for Treating Individuals with Co occurring Mental Health and Substance Use Disorders

    SBC: Praxis            Topic: 350

    Millions of U S adults suffer from a co occurring mental health and substance use disorder COD A COD is often difficult for providers to address and thus clients may experience poor treatment engagement symptom exacerbations homelessness incarceration and often utilize acute and emergency services increasing medical expenditures Currently the healthcare delivery system needs but does ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Online Training For Addressing Perinatal Depression

    SBC: Praxis            Topic: 104

    Project Summary The primary goal of this proposal is to develop implement and evaluate an online module to improve obstetric providersandapos knowledge skills and practices regarding perinatal depression There is a tremendous public health need for addressing this problem as upwards of in women suffer from perinatal depression Left untreated it has deleterious effects on maternal and bi ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Development Characterization and Commercialization of a Viably Frozen Patient Inclusive Hepatocellular Carcinoma Tumor Bank

    SBC: Woodland Pharmaceuticals LLC            Topic: 103

    Abstract Hepatocellular carcinoma HCC is a disease of growing incidence globally including in the US by per year With the recent success of anti viral therapies the etiology of HCC in the American population is projected to shift from viral HBV HCV hepatitis to primarily fatty liver disease in the near future Currently only one effective systemic therapy has been developed for HCC ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Development of Structure Based Potential for Protein Mapping

    SBC: ACPHARIS            Topic: 100

    The binding sites of proteins include smaller regions called hot spots that are major contributors to the binding free energy and hence are crucial to binding any ligand at that site Hot spots can be determined by screening libraries of fragment sized organic molecules for binding to the target protein by X ray crystallography or nuclear magnetic resonance NMR The computational mapping algori ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. My MESSAGE Improving Wayfinding and Reducing Challenging Behaviors in Persons with Dementia Through the Use of RFID Technology

    SBC: HEARTHSTONE ALZHEIMER CARE, LTD            Topic: NIA

    In the proposed study we will develop and evaluate a product called My MESSAGE Multimedia Ecopsychosocial Support System for Alzheimer s within Geriatric Environments which will circumvent the limitations of traditional visual cues and also provide unprecedented flexibility and precision for assisting with wayfinding and reducing other challenging behaviors in PWD The target consumer for MM w ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
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