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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Developing a small peptide to control autoimmune inflammation in type diabetes
SBC: Op-T-Mune, Inc Topic: NIAIDAbstract Type Diabetes T D affects an ever growing population While this disease typically has been associated with juveniles the disease in adult populations is rapidly increasing The defining clinical component is insulin loss which occurs because of sustained inflammation in the islets At present there is no means to prevent or reverse insulin loss A major inflammatory pathway in T D ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
DEVELOPMENT OF A NOVEL ANTIVIRAL TO TREAT AND PREVENT ACYCLOVIR RESISTANCE IN HUMAN OCULAR HERPES KERATITIS
SBC: FOX CHASE CHEMICAL DIVERSITY CENTER INC. Topic: NABSTRACT Infection of the eye by Herpes Simplex Virus HSV can result in Herpes Keratitis HK which is the leading cause of corneal blindness worldwide In the U S nearly individuals experience ocular herpes infections that are often recurrent and culminate in progressive corneal scarring and loss of vision The gold standard of care for HK is treatment with Acyclovir ACV that t ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Tools for site specific antibody immobilization for immunoassays
SBC: ALPHATHERA Topic: NAntibodies most commonly Immunoglobulin Gs IgGs are widely used in research and diagnostic assays due to their wide array of targets high specificity and proven efficacy In many of these immunoassays e g ELISAandapos s biosensors etc antibodies must be immobilized onto surfaces The sensitivity stability and longevity of antibodies used in this context are highly dependent on orien ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
eHealth Mobile Technology Connecting Young Adults to Routine Engagement eMCARE a theoretically and empirically driven mobile intervention to engage young adults in healthcare
SBC: NURELM, INC. Topic: NICHDeMCARE EHealth Mobile Technology Connecting Young Adults to Routine Engagement Young adults YAs ages have a worse health profile than adolescents or adults in their late twenties and thirties Most YAs in the US experience no preparation for the transition from pediatric to adult care often seeking care only through emergency department ED visits The results can be seen across issues ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Inhibitors of Hydrogen Sulfide Metabolism as a Novel Treatment for Heart Failure
SBC: FOX CHASE CHEMICAL DIVERSITY CENTER INC. Topic: NHLBIThe goal of this Phase I STTR grant application is to capitalize on our recent discovery of novel sulfide quinone oxidoreductase SQOR inhibitors by the design and preparation of new analogs for the treatment of heart failure that enable us to understand SAR so as to improve potency and optimize ADME PK properties Heart failure is a highly lethal disease affecting more than million adults in t ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Preparation of site specific antibody drug conjugates by proximity based sortase ligation
SBC: ALPHATHERA Topic: 103There has been growing interest in the use of antibody drug conjugates ADCs for the treatment of cancer as mounting data suggests an increase in anti tumor effectiveness and reduced toxicity compared with the administration of unlabeled antibodies in combination with chemotherapy The two ADCs that are currently approved by the FDA brentuximab vedotin Adcetris and ado trastuzumab emtansin ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
E training of Inmate Peer Caregivers for Enhancing Geriatric and End of life Care in Prisons
SBC: KLEIN BUENDEL, INC. Topic: NIAThe US has the highest incarceration rate in the world imprisoning people per The older adult segment of the prison population has more than tripled since and their health issues are common to free people who are years their senior Inmates over the age of have a death rate that is times that of prisoners aged US prison systems are facing sharply increased dema ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Screening for the autoimmune component of multiple sclerosis
SBC: Op-T-Mune, Inc Topic: NIAIDMultiple Sclerosis is an inflammatory neurodegenerative disease with autoimmune components that exacerbate and potentially initiate the disease Diagnosis is invasive time consuming relatively expensive and extremely difficult In fact no clear diagnostic test yet exist A major concern is that MS symptoms are identical to the symptoms of numerous other neurologic diseases OND as well as some ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Effects of LGM on a Primate Model of Asthma
SBC: Lignamed, LLC Topic: NIAIDPROJECT SUMMARY We previously demonstrated in mice that the major pathogenic features eosinophilic airway inflammation and airway hyperresponsiveness AHR were markedly enhanced in mice exposed to repeated social stress and these changes were associated with impaired glucocorticoid receptor GR expression and function In studies on non human primates rhesus macaques at the California Natio ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Development and Validation of SafeClose Mesh Augmentation System for Hernia Prevention
SBC: Paradigm Surgical LLC Topic: 300Incisional hernia IH can be prevented using prophylactic mesh placement PMP which involved placement of mesh to reinforce an abdominal fascia closure before herniation occurs at the index of surgery PMP reduced the absolute risk of IH with an acceptable complication profile Open abdominal surgery techniques remain commonplace and contribute to the estimated cases of IH performed in ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health